WormBase-Caltech Weekly Calls

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2016 Meetings

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December 1, 2016

Micropublication grant

  • Daniela and Karen working on
  • Pulled out papers that mention "unpublished" and "data not shown"
  • Working with Transgenome project and GSA
  • Deadline Dec 15th
  • Proposal for BD2K call, multiple agencies (NHGRI)
  • Focusing on curation process (as opposed to publication process)
  • Have "unpublished" data mentioned in one paper later published in another? Maybe, difficult to know
  • Could sample ~20 papers to check
  • Another approach could check how many chapters from PhD theses are unpublished
  • Could ask authors (source of personal communication) if they've ever published the data
  • Check BioArchive, how much is still unpublished 5 years out?
  • Could be a process where authors cannot say "data not shown" they need to micropublish
  • Any published reports about how much unpublished data there is?
  • What are the numbers for fly, mouse (other organism) papers?
  • Micropublications are something that AGR is interested in

GoToMeeting trial

  • Allows computer call-in or phone dial in
  • Reasonably priced, but costs add up if many people are dialing in with the toll-free number (8 cents per minute per person)
  • Allows for multiple webcams and screen sharing
  • People generally like it

Citace upload

  • January 13th, 2017


December 8, 2016

LinkOut from PubMed paper pages to WormBase paper pages?

  • GO recently established link outs from PubMed to AmiGO
  • TAIR links out from PubMed to TAIR paper pages
  • Do this for WB (and AGR)?
  • Can take a look at WB paper pages, maybe clean up, e.g. make less jargony

AGR meeting

  • Faceted search for data across MODs
  • Goal: Common gene report page
    • Minimal gene report page by March
      • gene id, names
      • gene concise description
      • gene sequences
      • gene location/structure
      • gene orthology
      • gene-disease connections
      • gene ontology (go-slim ribbons)
  • AGR use case meeting yesterday discussed outcome of Denver meeting
    • Figuring out the role of the use case working group with new working groups
  • GO slims - generic or organism-specific? Possibly both; we should see what works
  • Project manager? Maybe
  • Gene descriptions
    • ZFIN doesn't have them; could we take advantage of automated descriptions?

WormBase grant

  • Need to submit in May or September
  • What needs to be thought about for the renewal?
    • Datomic will continue (should be done by new grant cycle)
    • Curation
      • What's happening in community annotation?
        • We can use existing phenotype pipeline
        • Can encourage bulk data uploads
      • What data are we curating?
      • Noctua training and implementation
      • Disease curation becoming standard
      • Molecule curation
      • Physical interaction curation: most DBs farm out; we do our own
        • Common, basic datatype that could be curated by international curation efforts
      • Pathway curation
        • Can we establish automated pipelines to pull in pathway annotations from core data?

SObA graphs for gene ontology data


December 15, 2016

AGR use case working group

  • Members of use case WG will be delegated to smaller working groups to help build the AGR portal gene report page
  • Chris working with disease working group to build a disease widget on a gene report page

SObA graphs for gene ontology data

  • Raymond and Juancarlos are working on it
  • Have contacted Chris Mungall for advice

Gene enrichment analysis

  • Raymond working with David Angeles to create more enrichment analysis tools
  • To include GO term and phenotype enrichment analysis (hyper-geometric test)