WormBase-Caltech Weekly Calls

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GoToMeeting link: https://www.gotomeet.me/wormbase1

2018 Meetings

January

February 1, 2018

Automated gene descriptions - orthology

• Some genes have human orthology mentioned in automated descriptions, even though the orthology call has not been called in DIOPT
• WormBase uses EnsemblCompara and other methods (not aggregate method like DIOPT)
• Orthology synchrony is a challenge; WormBase and FlyBase may need to pay special attention to orthology calls and discrepancies
• DIOPT is purely automated, does not consider other information about orthology evidence
• We should be clear about how the orthology calls are made

Next upload

• Unclear of exact date
• Probably end of March

SimpleMine issue

• Redundant genes in input list are merged
• Should SimpleMine provide an option to keep redundancies?
  • Give option up front? Provide submission step to point out redundancies? Ask for choice?
• We can default to show row-by-row correspondence, and display the number of redundant entries