WormBase-Caltech Weekly Calls

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December 6, 2012

Concise descriptions

  • Concise descriptions tool as a pilot for community annotation
  • How can concise descriptions be generated on an automated basis?
  • Prioritize with genes with little to no known information
  • Focus on genes in other species
  • GBrowse-visible description (30 character limit)
  • Complex gene information will still be best handled manually
  • Brugia malayi good starting point; Also, Pristionchus and C. briggsae
  • Ralf Sommer would help generate concise descriptions
  • Working with Brugia community already
  • Could we select what type of GBrowse description is visible (potential drug targets, molecular function (GO term?), secreted proteases, resistance locus, etc.)? Using radio buttons, for example?
  • Use GO annotations in automated fashion?
  • Parasitic worm vs. Free-living worm descriptions (host, drugs, species-specific genes, etc.)
  • 30-character controlled vocabulary for genes?
  • Annotate (and then display) based on drug sensitivity, resistance, no effect? Show "potential" drug interactions?
  • Icons on genes indicating drug interaction, for example


PAINT meeting

  • Ranjana going to next week
  • PAINT: Panther tree-based transfer of GO annotations across species
  • Orthologs/paralogs adopt annotations


AMIGO update

  • Can display our ontologies now
  • User interface may take some time
  • Would be best if Raymond could work with a programmer (Juancarlos?)


Remark field display issues

  • Todd commented that he would like the "Remark" and "Summary" fields to display similar type of info across all pages/objects/data-types
  • Transgene curation (and others?) may need adjustment to what goes in the "Summary" and "Remark" field
  • May create new tag to accommodate info?


Upload

  • Data upload will be Dec 20th
  • Database build will happen second week of Janurary