Difference between revisions of "WormBase-Caltech Weekly Calls"

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[[WormBase-Caltech_Weekly_Calls_July_2014|July]]
 
[[WormBase-Caltech_Weekly_Calls_July_2014|July]]
  
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[[WormBase-Caltech_Weekly_Calls_August_2014|August]]
  
== August 7, 2014 ==
 
  
* Topic Curation
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== September 4, 2014 ==
** Working out pipeline for curation
 
** Collecting model/pathway diagrams from papers and reviews: should we make ?Picture objects for these?
 
*** Do we want to display these published diagrams on ?Paper pages and/or ?Topic pages
 
*** We need to determine copyrights/accessibility to images
 
** Would be good to automate identification of Review articles (or "non-primary" in general) in the Topic OA
 
*** This could be done at the bulk import step
 
*** Would require a new (possibly read-only) field in the Topic OA to indicate "primary" or "non-primary"
 
** Chris will look into whether "non-primary" articles are automatically excluded from the Curation Status Form
 
** The "Curation Status Omit" toggle in the Topic OA may become obsolete once we have a field/column for primary/non-primary status
 
** Current topic : Wnt signaling
 
** We have a list of 282 papers from PubMed search using "Wnt" search term (not Mesh term) and C. elegans (Mesh term)
 
** Finding all papers for a category/topic remains an ad hoc approach; different topics are harder or easier to find all papers for
 
** We can create a Textpresso category for topics, like "Wnt signaling"
 
  
 
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* Topic 1
* WormBase Ontology Browser
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* Topic 2
** Needs documenting
 
** Once everything is clarified, will be pushed to the live site
 
 
 
== August 14, 2014 ==
 
 
 
* WormBase Ontology Browser (WOBr)
 
** Should be ready but may need some additional testing before pushing to staging site
 
** Juancarlos will push to staging during meeting
 
** Curators should test this afternoon (on staging) and report any issues before 5pm
 
 
 
* DataBase call this morning (and every Thursday that doesn't have a site-wide call)
 
** Thomas Down testing Datomic (costs money) and Neo4J (very slow)
 
** May look again at DynamoDB
 
** No DB has been officially chosen
 
** Will have an Amazon AWS for collaboration.
 
** Expand smallace into bigger mediumace.
 
** Demo off one database for advisory board meeting.
 
 
 
* SAB
 
** Paul Sternberg back next week; will settle travel plans then
 
** What advisors are attending?
 
** What feedback do we want to get from advisors?
 
** How to show curation/DB progress? What stats/numbers to show?
 
** We want big picture feedback from biologist advisors; what's useful to the community? What should we prioritize?
 
** Karen: Perhaps a question to ask is "what are the main questions they are trying to answer when they go to the website?".  When they explore a gene or protein function, what is it that they would want to see, and how?  I don't think we are missing information so much as a lack of integration of the information at the model level, for example, variation phenotype affects linked to altered protein domain function
 
 
 
* Belated apologies from Mary Ann - clash of evening events.
 
 
 
== August 21, 2014 ==
 
 
 
* Generating a Site-Map for WormBase
 
** Use a crawler to generate? Output would need to be made human-readable
 
** We could use the legacy site as a site map
 
* Citace upload report modifications
 
** wikipage here: [[Citace_upload_report]]
 
** Goals of this report
 
*** Summary of the uploaded data classes/objects - this summary should be blind to requests from curators and should alert Caltech to missing data classes or severe changes in numbers of objects within preexisting data classes
 
*** Summary of curation work - this summary should be curator driven, in some cases the summary will require a more involved aceperl query to get at the actual annotation rather than a straight data class object number.
 
** Can we get a comparison for those data that are curated through postgres? It would be very helpful to be able to compare the changes in postgres with the changes in the Citace upload.
 
** Can we automate the generation of this report to make it easier to change and track?
 
** Regardless of manual or automated report generation when there is a model change or data class addition/subtraction, the responsible curator needs to inform Wen of the need for compensatory modification in the report.
 
 
 
== August 28, 2014 ==
 
 
 
* Curation Statistics for SAB
 
** Curators should send Chris all stats for their respective data types: total papers curated, total backlog, false positives
 
** Can we ignore SVM results for certain data types?
 
** Can we include Textpresso search results for relevant data types?
 
** Curators that use a Textpresso pipeline: Karen, Ranjana, Xiaodong, (Daniela?), Mary Ann
 
** Can we get detailed web usage statistics on particular datatypes?
 
** We want to articulate our priorities to the SAB; get feedback
 
** RNAi curation could get up to speed in 5 years if we have two FTEs on RNAi curation
 
** Are there certain genes that have less phenotype coverage that we should prioritize?
 
 
 
* Database migration call
 
** MongoDB, CouchDB, Neo4J, Datomic, OrientDB, postgreSQL, Cassandra candidates
 
** Neo4J likely ruled out because of slow performance
 
** Will compare performance of Datomic vs. Postgres and ACEDB, etc.
 
** Datomic has good history tracking
 
** Thomas Down has experience with Datomic
 
** Probably won't go with a relational database
 
** We should use the Gene page (webpage) as a demo/example of what we want to try to emulate
 
** Adam (from Lincoln's group) working with OrientDB (graph database)
 
 
 
* Citace Upload Report
 
** Classes/datatypes missing from Citace Upload Report
 
** Karen started a Wiki page to capture this info: [[Citace_upload_report]]
 
** Curators should take a look and make sure it is properly filled out for their data types
 
** Columns are present in the table to make requests for certain numbers in Citace Upload Report and/or the Build Report
 
** Wen will take requests for queries to Citace etc. to add data to report
 
 
 
* UniProt linking to and from WormBase
 
**UniProt would like us to add information about some specific curated datatypes to a file we already supply that maps paper and gene identifiers
 
**Kimberly and Juancarlos will work on this
 
**Need to clarify with UniProt how links back to WormBase can/will be implemented
 
 
 
* Paul S going to NIH for data science meeting next week
 
 
 
* FlyBase pushing human disease curation
 
 
 
* LEGO backend updates
 
** Still need to get some backend logistics sorted out
 
** Communication between Michael Muller and Chris Mungall
 
** OA-like interface for Noctua?
 

Revision as of 17:24, 3 September 2014

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September 4, 2014

  • Topic 1
  • Topic 2