Difference between revisions of "WormBase-Caltech Weekly Calls"

Revision as of 17:44, 6 December 2012

Concise descriptions

Concise descriptions tool as a pilot for community annotation
How can concise descriptions be generated on an automated basis?
Prioritize with genes with little to no known information
Focus on genes in other species
GBrowse-visible description (30 character limit)
Complex gene information will still be best handled manually
Brugia malayi good starting point; Pristionchus and C. briggsae
Ralf Sommer would help generate concise descriptions
Working with Brugia community already
Could we select what type of GBrowse description is visible (potential drug targets, molecular function (GO term?), secreted proteases, resistance locus, etc.)? Using radio buttons, for example?
Use GO annotations in automated fashion?
Parasitic worm vs. Free-living worm descriptions (host, drugs, species-specific genes, etc.)
30-character controlled vocabulary for genes?
Annotate (and then display) based on drug sensitivity, resistance, no effect? Show "potential" drug interactions?
Icons on genes indicating drug interaction, for example

PAINT meeting

AMIGO update

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 *Annotate (and then display) based on drug sensitivity, resistance, no effect? Show "potential" drug interactions?
 *Icons on genes indicating drug interaction, for example
+PAINT meeting
+*Ranjana going to next week
+*PAINT: Panther tree-based transfer of GO annotations across species
+*Orthologs/paralogs adopt annotations
+AMIGO update
+*Can display our ontologies now
+*User interface may take some time
+*Would be best if Raymond could work with a programmer (Juancarlos?)