Difference between revisions of "WormBase-Caltech Weekly Calls"

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**i.e. keep the original timestamp or create new one
 
**i.e. keep the original timestamp or create new one
 
**Will likely not create new timestamp
 
**Will likely not create new timestamp
 +
 +
 +
Life_stage switch from names to IDs
 +
*Curators need to let Juancarlos know if the OA dumper is working as expected on Mangolassi (sandbox)
 +
*Once ready, Juancarlos can move the dumper to Tazendra
 +
 +
 +
Interaction model change
 +
*Will add two tags to the Interactor_info hash:
 +
**Intragenic_effector_variation
 +
**Intragenic_affected_variation
 +
*Will add four tags to the main Interaction model:
 +
**Unaffiliated_variation
 +
**Unaffiliated_transgene
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**Unaffiliated_antibody
 +
**Unaffiliated_expression_pattern
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*These changes will accommodate intragenic genetic interactions and unsuccessful object-to-gene mappings

Revision as of 16:43, 17 May 2012

2009 Meetings

2011 Meetings


2012 Meetings

January

February

March

April


May 3, 2012

Curator Timestamps

  • Determining what data was provided directly by curator vs. what was populated automatically (e.g. mapping scripts)
  • Older data provided by curators that are no longer here will be problematic
  • We should archive all data-processing scripts in GitHub
  • Scripts can be made to create a unique timestamp that identifies that script after the fact


Interaction model change

  • Pulling Variation, Transgene, Antibody, and Expr_pattern tags out of the Interactor_info hash and into the main model
  • This was originally to be able to capture intragenic interactions
  • The problem is the inherent disconnect between an interactor entity (e.g. gene) and these objects
  • Making this change would force a post-curation mechanism that ties these entities together for intuitive data display
    • Such a linking mechanism may be error prone, faulty, and potentially a headache for the web team
  • Is there a better way to handle this type of data?
  • Chris will discuss with Todd to see how much of a problem this would pose to the web team


May 17, 2012

Life_stage model

  • Include species tag?
  • Create an ontology of life stages for different species
  • There are differences in nomenclature
  • Include Matt Berriman and Mark Blaxter in conversation on this?
  • Could include species abbreviation as prefix: e.g. Ppa_L1, Cbr_L3, etc.
  • How should we provide descriptions for each life stage?
  • Two main proposals:
    • 1. General ontology of names: L1, embryo, dauer, adult, etc.
    • 2. Go from most general to most specific
      • e.g. Larval stage -> L1 -> Ppa_L1
  • Maybe make a C. elegans Slim Ontology
  • Anyone requesting a new life stage should provide a description


Adding 3'UTR tag for transgene

  • Capture gene name (not necessarily DNA text)
  • Ignore unc-54 3'UTR
  • Triage by cases that come up for interaction or gene regulation events


Transgene Names

  • WBPaperIDEx vs WBPaperID_Ex (underscore)
  • Would be good to have consistent naming scheme
  • Juancarlos needs to know if any curator wants/needs a history of the name change
    • i.e. keep the original timestamp or create new one
    • Will likely not create new timestamp


Life_stage switch from names to IDs

  • Curators need to let Juancarlos know if the OA dumper is working as expected on Mangolassi (sandbox)
  • Once ready, Juancarlos can move the dumper to Tazendra


Interaction model change

  • Will add two tags to the Interactor_info hash:
    • Intragenic_effector_variation
    • Intragenic_affected_variation
  • Will add four tags to the main Interaction model:
    • Unaffiliated_variation
    • Unaffiliated_transgene
    • Unaffiliated_antibody
    • Unaffiliated_expression_pattern
  • These changes will accommodate intragenic genetic interactions and unsuccessful object-to-gene mappings