Difference between revisions of "WormBase-Caltech Weekly Calls"

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==2012 Meetings==
 
==2012 Meetings==
  
 
==January 5, 2012==
 
 
Interactions patch
 
*One large scale paper omitted from upload
 
*Patch sent in; all OK
 
 
 
Integration of 3rd party data
 
*BioGRID, Gene Orienteer, Interolog database, etc.
 
*Gene Orienteer
 
**May only want interactions above a threshold
 
*Interolog database
 
**Get gene pages linked to their database
 
**Display data on gene pages, but keep display distinct?
 
*FlyBase links out to BioGRID, Interolog
 
*modEncode Transcription Regulatory Network display/diagrams?
 
 
 
New site release with WS230?
 
*About 2 months
 
 
 
Textpresso Interaction Sentences
 
*Now have sentences associated with interactions
 
*Need to discuss what sentences should be kept as adequate evidence of interaction and placed in remarks
 
*See if Textpresso can pull out paragraphs (or +/- 4 sentences?) for each sentence to see context
 
*Can we devise some automation to handle interaction updates?
 
 
 
 
== January 12, 2012 ==
 
 
SVM
 
*Genetic Interaction SVM
 
*How well does it work?
 
*Do we have sentences?
 
*Kimberly will follow up with Xiaodong
 
*For HIV papers?
 
 
 
Human Diseases Connections
 
*Should be on new gene pages
 
*Browse function not yet fully functional
 
*Search with autocomplete available
 
*Table from 2000 Review, human/C. elegans orthologs and diseases - put on website?
 
*Indexed ACEDB data used for searches; create table from indexed data?
 
*Textpresso pipeline flags relevant disease papers; can info be added to database?
 
*?Human_disease model vs tag in ?Gene model?
 
*Similar discussion to ?Process model discussion
 
*Let's propose a ?Human_disease model; see what objections/suggestions anyone has (EBI?)
 
*Will follow the OBO/NCBI human disease ontology
 
 
 
Gloworm links
 
*Raymond made links from Anatomy pages to Gloworm site
 
*Can view movie relevant to Anatomy object at Gloworm
 
*Gloworm seems to only work on Macs (firewalled on Windows, doesn't work at all on Linux)
 
*Can we add an Apple symbol/logo next to Gloworm links on new site?
 
**Logo difficult, but we could add a text caveat
 
**New window opens with links; users should see error and be able to send Bill Mohler a message
 
 
 
Ontology Searches
 
*Status?
 
*Gary and Karen talking about fixing/cleaning up Phenotype Ontology
 
*Would be useful to have a filter on ontology searches
 
*Phenotype search available now, but no filters
 
*New search features not likely to be made in near future
 
*Intermine may be better tool for this
 
 
 
Genetic Interactions
 
*Rose discussed genetic interaction ontology with BioGRID et al in December
 
*BioGRID will stick with older terms (at least for now) as SGD and Entrez Gene need to also be on board
 
*Chris will review older 'Genetic' interactions with new terms as a proof of concept
 
*Can send results to BioGRID, SGD, and Entrez Gene
 
 
 
GSA markup
 
*Flybase wants authors to take care of all markup QC
 
*Pipeline: Author QC -> DJS -> Flybase check
 
*Flybase has minimal QC Fast service
 
*Michael added an 'UNDO' button for QC Fast
 
*Remove author ability to add links?
 
 
 
SVM Computers in Church 63
 
*SVM papers still in review (long process)
 
*Need to wait until SVM paper accepted before moving those computers
 
 
 
== January 19, 2012 ==
 
 
 
Parsing Legacy data into database
 
*Need some model changes to get the data in
 
*Model changes would be to:
 
** Add an Ease_of_scoring (ES) tag to #Phenotype_info, and
 
** Add a Mating_efficiency tag under ?Variation
 
 
 
Rescue_by_transgene tag
 
*If a transgene rescues an allele, it is placed under Rescue_by_transgene tag in the ?Variation class
 
*Move Rescue_by_transgene tag to #Phenotype_info in context of an Allele/Variation
 
*Can we display the transgene summary (i.e. genotype) in the Variation page? Yes
 
 
 
Changing author names in abstracts
 
*Changing the text/authors of an abstract was decided to be not allowed
 
*Is this a work issue or just a policy issue?
 
*Both, but most importantly a policy issue
 
*We get asked to make many changes to abstracts (sometimes content)
 
*It was decided (for fairness) that we wouldn't make any changes
 
*Polls were already taken at International meeting; consensus is that no changes will be made
 
*Formalize an 'Erratum' remark; Author(s) can submit?
 
*Authors need to login, verify their identity and authorship before being able to make an Erratum comment
 
*Occasionally we may need to verify/resolve issues; that's OK
 
 
 
SPELL download
 
*Users can download all (gene-centric, WormBase-parsed) SPELL data
 
*Wen wants to place the entire SPELL download on the FTP site
 
*Wen can send it to Todd
 
 
 
RNAi probe mappings
 
*EBI will eventually take over RNAi probe mappings to genome
 
*EBI already maps genomic coordinates to genes
 
*If EBI can take over the first step of mapping, we can develop an RNAi OA
 
*Ideally, curators could submit: PCR product names (e.g. sjj_W02C12.3), raw DNA sequence, primers
 
*Maybe EBI only wants DNA text? Need to check with them
 
 
 
ePCR
 
*Old script
 
*Any newer scripts available? Substitution?
 
 
 
SVM paper accepted
 
*Computers in Church 63 may be able to be moved
 
*Michael and Yuling need to check the data on them
 
*Need to touch base with Ruihua to ensure the computers can be moved
 
 
 
 
== January 26, 2012 ==
 
 
Luke Hutchison talking
 
 
 
SPELL server hanging on Amazon
 
*Raymond working on fixing
 
 
 
Interaction Model
 
*New ?Interaction model proposal consolidates current ?YH, ?Gene_regulation, and ?Interaction classes
 
*Various changes will be made to current version
 
 
 
SVM paper done
 
  
  

Revision as of 18:08, 2 February 2012

2009 Meetings

2011 Meetings


January


2012 Meetings

February 2, 2012

EPIC data into WormBase

  • Daniela spoke to John Murray
  • Need to modify model and display for data
  • 3D movies as ?Movie objects


Endrov

  • Tom Burglin and student Johan Henriksson developed Endrov.net (http://www.endrov.net)
  • May be able to incorporate Endrov visualizations of Blender model and cell lineage into WormBase website?
  • Need to talk to Todd and Web team


Elsevier legal issues

  • Science-direct website links to-and-from WormBase website
  • Daniela still working with contacts at MGI (Mouse Genomics Institute/Jackson Labs) & Elsevier
  • MGI already has established links with Elsevier


New ?Interaction model

  • Update old objects and speak to web team about new model before officially incorporating new ?Interaction model