Difference between revisions of "WormBase-Caltech Weekly Calls"

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[[WormBase-Caltech_Weekly_Calls_September_2011|September]]
 
 
== September 1, 2011 ==
 
 
 
 
 
SPELL
 
*Raymond and Wen worked on putting on Amazon cloud
 
*SPELL running on Amazon cloud
 
*What next?
 
*Need to be careful about running a cloud instance
 
*Elastic IP? No, not yet
 
*What are the requirements for SPELL? Free instance is currently sufficient
 
*Need more memory for the start-up process
 
*Haven't yet figured out a way to do stress tests
 
*SPELL does not have many users (~500 queries per month)
 
*Free tier available for only 6 months and then gone
 
*Need to determine what the build requirements are (needed for every build/release)
 
*Only want one copy of it (so we aren't paying twice)
 
*Single canonical AMI
 
*First step, firgure out build requirements (need more memory during build?) and runtime requirements
 
*Free instance 2GB memory (upgraded) for build, 600MB memory OK for runtime
 
*What will it take to maintain one of these instances for a year?
 
*Double up SPELL queries with the main WormBase instance on the cloud to consolidate?
 
*How to more fully incorporate SPELL into WormBase?
 
*Integrate SPELL into the new WormBase App? (branding, tracking access)
 
*Running under Apache; Ruby-on-Rails
 
*Could maintain cloud instance for now and see how it will function (and what it will cost) over the year
 
*Better if elastic IP assigned (25 cents/day? Or free once attached to an instance?)
 
*Can it run in a micro-instance? Yes
 
*$175/year for cpu plus disk space and transfer
 
*Switch credit cards (from Raymond's to Caltech)
 
*Follow logs to assess likely costs later on
 
 
 
 
 
== September 8, 2011 ==
 
 
 
 
 
NAR Paper
 
*Ranjana having Editing trouble
 
*Karen will format tomorrow for the bibliography and so will be off Google Docs
 
*Paper due at end of October
 
*There is discussion of submitting other papers to other journals; Worm?
 
*Want consistent presence in Worm? Ad space?
 
*Journals: NAR, BMC (Bioinformatics etc.), Worm, Database
 
*What content would be appropriate for each journal? Who is the target audience?
 
*Ongoing short editorial (or something) in each issue of Worm? "Hints from WormBase"?
 
 
 
 
 
Caltech Internet/Network issues yesterday
 
 
 
 
 
Aldrin Montana
 
*Difficulty installing AMIGO on computers
 
*Busy with it until had to go back to school
 
 
 
 
 
RNAi Curation Standard Operating Procedure (SOP)
 
*Written on WormBase Wiki under Caltech Documentation > RNAi
 
 
 
 
 
SVM transition
 
*From Ruihua to Yuling
 
*Ruihua will meet with Yuling next week to discuss
 
*There likely will be issues during the transition
 
*Should alert Hinxton/EBI and Wash U
 
 
 
 
 
== September 15, 2011 ==
 
 
 
 
 
Worm Paper?
 
*Brainstorming topics/ideas
 
*Topics:
 
**Overview
 
**New Website
 
**Expression patterns (image curation and 3D graphics)
 
 
 
 
 
Picture Curation
 
*Adrian back at OICR, fixed some picture displays
 
*Transgenome
 
*Working on import pipeline
 
*Contacted Worm Atlas for GFP images
 
*Automated permissions request
 
**Contacted ZFIN, since they have been using images for years
 
**Requested permission for each image, too much work
 
**No luck with Wiley, Nature, Science, etc.
 
**Maybe collaborate with ZFIN to have greater influence
 
*Elsevier gave blanket permission for expression pattern images
 
*Nature Publishing Group needs a list of each image that we request permission for
 
*Eventually want images other than just expression patterns (e.g. phenotypes)
 
*Obviously automated e-mails have less influence/pull
 
*Need formal statement of permission from Genetics
 
*Elsevier publisher suggested putting a WormBase logo next to article in Science Direct
 
**A link can be made which would redirect users to the relevant WormBase paper page
 
 
 
 
 
Expression Cluster
 
*Wen finished recuration of expression cluster papers
 
*Still have papers IDed from Author First Pass with microarray data
 
**Papers don't have microarray data but other expression cluster-related info
 
**Authors aren't responding to e-mails
 
**Detailed info does not have details for microarray curation. How to handle?
 
 
 
 
 
SVM Transition
 
*Ruihua working on code for SVM
 
*Yuling still planning to meet with Ruihua
 
 
 
 
 
WormMart
 
*OICR back in charge
 
*OICR doesn't have access to the server that WormBase is running on (caprica)
 
*Paul has usernam/password for root access to server
 
*OICR working with BioMart developers
 
*New data loader that should improve function
 
*Want to give access to BioMart to existing configuration
 
*BioMart will implement new data loader and then hand back over to OICR for maintenance
 
 
 
 
 
Genetic Interaction Ontology
 
*Almost arrived at concensus with BioGRID (Rose, Andrew)
 
*Mike Tyers was happy with the development of the ontology
 
*Once complete can be sent to Charlie Boone, Fritz Roth, etc. to review
 
 
 
 
 
Textpresso
 
*Textpresso for HIV and for Wnt signalling
 
 
 
 
 
Orcid (Library of Congress)
 
*Give each person, website, etc. a unique ID via publications
 
*Global scale
 
*May be interested in WormBase IDs (proof of concept for Orcid)
 
*Pre-populate their system with our data
 
*Initial launch will be self registration -> how to catalog people automatically
 
 
 
 
 
GSA GO Linking
 
*Going to go ahead with GO term linking for GSA paper abstracts
 
*Arun needs to streamline the pipeline to accommodate
 
 
 
 
 
 
 
== September 22, 2011 ==
 
 
 
 
 
Computers
 
*Three computers in Church 63, Raymond, Yuling have access to all three
 
*Backing up files
 
*Will turn off/on and check
 
*Todd has access as well; need to monitor WormMart during shut down, etc.
 
 
 
 
 
Genetic Interactions Ontology
 
*(Chris) Will send around before next meeting to review/discuss
 
*Have incorporated some new terms like "over-suppression"
 
*Have powerpoint slides to visually depict types of genetic interactions on a phenotype scale
 
 
 
 
 
Picture curation
 
*(Daniela) Getting official confirmation of permission for images
 
 
 
 
 
Beta website
 
*We should actively report issues: dead ends, errors, missing data
 
*Missing AQL and WBQL query pages?
 
*Use issue reporter or BitBucket(?)
 
 
 
 
 
Pharyngeal Connectivity Data
 
*Working on reconstruction (Raymond)
 
*Discuss with Erik Jorgensen
 
*Look over cortex paper
 
 
 
 
 
Concise descriptions
 
*Tested on sandbox
 
*Should be live on tazendra soon
 

Revision as of 16:23, 6 October 2011