WormBase Genomes
Contents
WormBase Genomes
This is a record of the current and proposed set of genomes in WormBase.
We may, of course, alter our plans for which species to include as circumstances dictate and so the list of organisms which should be included should be treated as somewhat tentative.
Clade
The Major Clades of Blaxter et al 1998 ("Bclades"), as systematised by De Ley and Blaxter 2002-2004.
Tiers
The different genomes in WormBase are classified in various tiers which depend on the amount of curation effort we are able to put into maintaining them.
Tier I - All efforts are made to curate the gene structures and any other genetic or metabolic information. Only C. elegans is in this group.
Tier II - Efforts are made, where practical, to manually curate the gene structure and possibly some other genomic information. WormBase 'owns' the assembly in the ENA and GenBank so that new gene annotations can be submitted to the ENA/GenBank by WormBase.
Tier III - We will set up the genome on WormBase with any gene structures that the authors of this genome have predicted. No further curation efforts are made by the WormBase consortium.
Tier IV - Proposed tier for organisms with only transcriptome information and no coherent genome. There are no examples of this in WormBase at present.
Tier V - Proposed tier for organisms with only genome information and no coherent transcriptome. There are no examples of this in WormBase at present.
Genome
The Genome column in the table gives the assembly size and a link to the genome in WormBase, or the approximate size if it has not been assembled.
Gene
The Genes column in the table indicates whether gene structures have been added to WormBase.
The current genomes
Clade | Species | NCBI Taxon | Tier | Genome | Genes | Origin | Comments |
---|---|---|---|---|---|---|---|
V | Caenorhabditis briggsae | 6238 | II | 108419768 bp | Yes | WashU | [Sept 2010] New assembly from Erich Haag being worked on. [Feb 2011] updated in WS224 |
V | Caenorhabditis species 9 strain JU1422 |
870437 | V | 204396809 bp | WashU | released in WS226. WARNING the genome sequence contains contaminations | |
V | Caenorhabditis species 5 | ? | V | WashU | released in WS226. | ||
V | Caenorhabditis remanei | 31234 | II | 145500347 bp | Yes | WashU | |
V | Caenorhabditis species 11 strain JU1373 |
886184 | III | 79321433 bp | Yes | WashU | genome and deNovo gene set released in WS226. Replaced by RNAseq based gene set in WS227. |
V | Caenorhabditis brenneri species 4 |
135651 | II | 190421492 bp | Yes | WashU | [Jan 2011] The current assembly contains quite a bit of heterozygosity. Warning WS223-WS226 genome assembly is not in sync with the annotation files or INSDC. Please use WS227+ |
V | Caenorhabditis elegans strain Bristol N2 |
6239 | I | 100272276 bp | Yes | WashU/Sanger | |
V | Caenorhabditis species 7 strain JU1286 |
870436 | V | WashU | released in WS226. WARNING the genome sequence contains contaminations | ||
V | Caenorhabditis japonica | 281687 | II | 166565019 bp | Yes | WashU | [Jan 2011] New/improved assembly is being worked on at WashU. [Oct 2011] new assembly in WS227 |
V | Caenorhabditis angaria species 3 strain PS1010 |
96668 | III | 79761545 bp | Yes | CalTech | Added to WormBase in release WS218. [Jan 2011] This species now has an official name of C. angaria |
V | Haemonchus contortus | 6289 | III | 297975349 bp | Yes | Sanger | Added to WormBase in release WS209. |
V | Heterorhabditis bacteriophora | 37862 | V | 76974349 bp | WashU | [Jan 2011] Submitted to GenBank - Accession: EF043402 [Sep 2011] Gene set and Annotations are being worked on. [Nov 2011] on WormBase as of WS229 | |
V | Pristionchus pacificus | 54126 | II | 172773083 bp | Yes | WashU/MPI | [16 December 2010] Updated to the newest assembly and geneset in WS221 |
V | Steinernema carpocapsae | 34508 | III | 230 Mb | LANGEBIO / CalTech | [May 2011] Being assembled. | |
IV | Meloidogyne incognita | 6306 | III | 82095019 bp | INRA | Added to WormBase in release WS205. Genes are not yet available. | |
IV | Meloidogyne hapla | 6305 | III | 53017507 bp | Yes | NCSU hapla.org | Added to WormBase in release WS204. |
IV | Strongyloides ratti | 34506 | III | 52638471 bp | Sanger | [Jan 2011] draft assembly in GenBank, released in WS226 | |
IV | Bursaphelenchus xylophilus | 6326 | III | 74561461 bp | Yes | Sanger | [Sept 2011] published in PLOS Pathogens [Nov 2011] added to WormBase in WS229 |
III | Ascaris suum | 6253 | III | 272782664 bp | Yes | Davis | [Oct 2011] integrated the Davis genome without a reference gene set. [Nov 2011] added a reference gene set |
III | Brugia malayi | 6279 | III | 95814443 bp | Yes | TIGR -> WashU/Sanger | [Sept 2010] Currently using the old TIGR assembly. Waiting for WashU (did assembly) and Sanger (did gene models) to publish, then we will use the new assembly. [Dec 2010] merged Augustus gene predictions from Erich Schwarz into WS216 |
I | Trichinella spiralis | 6334 | III | 56779425 bp | Yes | WashU | [Sept 2010] Being assembled. [Feb 2011] published in Nature. [Mar 2011] added to WormBase in WS225 |
Genomes coming soon
Clade | Species | NCBI Taxon | Tier | Genome | Genes | Origin | Comments |
---|---|---|---|---|---|---|---|
V | Caenorhabditis drosophilae | 96641 | III | WashU | [Sept 2010] being assembled | ||
V | Caenorhabditis elegans strain DR1035 |
6239 | III | 100 Mb | Mark Blaxter | status unclear | |
Onchocerca volvulus | 6282 | III | Sanger | ||||
Globodera pallida | 36090 | III | Sanger | ||||
Nippostrongylus brasiliensis | 27835 | III | Sanger | ||||
Strongyloides ransomi | 553534 | III | Sanger | ||||
Teladorsagia circumcincta | 45464 | III | Sanger | ||||
Trichuris muris | 70415 | III | Sanger |
Phylogeny
Given my understanding of the current phylogenetic literature (and based on personal communications with Karin Kiontke,David Fitch and Mark Blaxter), the correct guide tree would be:
((((((((((((C.briggsae,C.sp9),C.sp5),C.remanei),(C.sp11,C.brenneri)),C.elegans),(C.sp7,C.japonica)),C.angaria),(H.contortus,H.bacteriophora)),P.pacificus),((M.incognita,M.hapla), (S.ratti,B.xylophilus))),(A.suum,B.malayi)),T.spiralis);