WBConfCall 2016.09.01-Agenda and Minutes
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Contents
Agenda
Standing items
Updates from AGR working groups
- Use-case
- Disease / Phenotype
- Orthology
- Tools
Help Desk tickets requiring attention
- User asking about use of RESTful API; https://github.com/WormBase/website/issues/5069
Minutes
Todd
- Was in a car accident; will need to minimize work load and screen time (emergencies only for now)
- Should we put the next build (WS256) on hold? Probably not. OICR won't need to start the working on WS256 for ~4 weeks
- Sibyl could possibly attempt to stage WS256, Juancarlos could provide assistance
Working Groups
Use Cases
Disease/Phenotype
- 2 meetings so far
- What objects do people curate to?
- What are the ontologies and controlled vocabularies that are used?
- There's a mixed bag; group will work on defining standards that everyone can use
- The Disease Ontology (DO) was decided to be a central ontology to use; some funding for DO in question
- Mouse group has been working heavily with DO and OMIM
- OMIM have their own curators and annotation style, not quite ready for receiving input from outside databases/groups
- Discussing curation of NOTs; when a disease model might be expected, capture when it doesn't turn out to be
Orthology
- Only 3 members (PIs) up until this week; others joined this week
- Currently working on defining canonical protein sets
- Would use UniProt reference proteome; up to date for some organisms (yeast, fly, worm), not all (not mouse, zebrafish, rat)
- UniProt working on getting up to date
- Canonical zebrafish protein set defined by Ensembl/Havana(sp?)
- Why doesn't UniProt have an up to date protein set for zebrafish?
- Mouse: money/effort spent on curating protein sets for mouse at EBI; not clear how mouse databases (MGI) use the Ensembl data
- Rat canonical protein set also not clearly defined in UniProt
- Will learn more in upcoming meeting