Difference between revisions of "WBConfCall 2016.09.01-Agenda and Minutes"

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* OMIM have their own curators and annotation style, not quite ready for receiving input from outside databases/groups
 
* OMIM have their own curators and annotation style, not quite ready for receiving input from outside databases/groups
 
* Discussing curation of NOTs; when a disease model might be expected, capture when it doesn't turn out to be
 
* Discussing curation of NOTs; when a disease model might be expected, capture when it doesn't turn out to be
 +
 +
=== Orthology ===
 +
* Only 3 members (PIs) up until this week; others joined this week
 +
* Currently working on defining canonical protein sets
 +
* Would use UniProt reference proteome; up to date for some organisms (yeast, fly, worm), not all (not mouse, zebrafish, rat)
 +
* UniProt working on getting up to date
 +
* Canonical zebrafish protein set defined by Ensembl/Havana(sp?)
 +
* Why doesn't UniProt have an up to date protein set for zebrafish?
 +
* Mouse: money/effort spent on curating protein sets for mouse at EBI; not clear how mouse databases (MGI) use the Ensembl data
 +
* Rat canonical protein set also not clearly defined in UniProt
 +
* Will learn more in upcoming meeting

Revision as of 16:11, 1 September 2016

Agenda

Standing items

Updates from AGR working groups

  • Use-case
  • Disease / Phenotype
  • Orthology
  • Tools

Help Desk tickets requiring attention

Minutes

Todd

  • Was in a car accident; will need to minimize work load and screen time (emergencies only for now)
  • Should we put the next build (WS256) on hold? Probably not. OICR won't need to start the working on WS256 for ~4 weeks
  • Sibyl could possibly attempt to stage WS256, Juancarlos could provide assistance

Working Groups

Use Cases

Disease/Phenotype

  • 2 meetings so far
  • What objects do people curate to?
  • What are the ontologies and controlled vocabularies that are used?
  • There's a mixed bag; group will work on defining standards that everyone can use
  • The Disease Ontology (DO) was decided to be a central ontology to use; some funding for DO in question
  • Mouse group has been working heavily with DO and OMIM
  • OMIM have their own curators and annotation style, not quite ready for receiving input from outside databases/groups
  • Discussing curation of NOTs; when a disease model might be expected, capture when it doesn't turn out to be

Orthology

  • Only 3 members (PIs) up until this week; others joined this week
  • Currently working on defining canonical protein sets
  • Would use UniProt reference proteome; up to date for some organisms (yeast, fly, worm), not all (not mouse, zebrafish, rat)
  • UniProt working on getting up to date
  • Canonical zebrafish protein set defined by Ensembl/Havana(sp?)
  • Why doesn't UniProt have an up to date protein set for zebrafish?
  • Mouse: money/effort spent on curating protein sets for mouse at EBI; not clear how mouse databases (MGI) use the Ensembl data
  • Rat canonical protein set also not clearly defined in UniProt
  • Will learn more in upcoming meeting
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