Gene Ontology

Gene Ontology curation at WormBase is performed through several different pipelines:

1. Manual curation of the literature

2. Semi-automated, Textpresso-based curation of Cellular Component and Molecular Function

3. Phenotype2GO mappings for Biological Process curation (both VariationPhenotype2GO and RNAiPhenotype2GO)

4. InterPro2GO mappings for sequence-based IEA annotations

5. Reference Genome Inferential Annotations

Manual curation

• Reference Genome (see also Reference Genome Inferential Annotations)

1. Lung Development Targets (November 2009 - February 2010)

Semi-automated curation

• CCC - GO Cellular Component Curation using Textpresso

1. dictyBase
2. FlyBase
3. TAIR
4. WormBase

• MFC - GO Molecular Function Curation using Textpresso

Phenotype2GO pipeline

• Phenotype2GO pipeline SOP
• Phenotype2GO Mappings File
• Phenotype2GO Mappings Sept. 09

Reference Genome Inferential Annotations

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