Difference between revisions of "Drugs"
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Revision as of 17:49, 15 April 2013
C. elegans is being used to study:
- metal toxicity and detoxification
- the effects of a drug/chemical on disease phenotypes
- identify gene targets for a given drug/chemical
- mode of action of a drug/chemical (MOA)
Types of drugs being studied include:
- Antifungal agents
- Antimicrobial agents
- Antiparasitic drugs--Aldicarb, Ivermectin, Levamisole
- Anti-depressants--Fluoxetine, Imipramine
- Anaesthic--Halothane
- Anticancer drugs--Farnesyltransferase inhibitors (FTIs)
- Anticonvulsants--Ethosuximide, Arimethadione
- Alkaloid drugs--Nicotine
- Immunosuppressants--Prednisone
- Nutritional supplements--Resveratrol, Gingko biloba
- Opioid toxins--MPTP/MPP+
- Pychoactive drug--Ethanol