WormBase Genomes

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Revision as of 16:11, 24 September 2010 by Mh6 (talk | contribs) (→‎Phylogeny)
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WormBase Genomes

This is a record of the current and proposed set of genomes in WormBase.

Tiers

The different genomes in WormBase are classified in various tiers which depend on the amount of curation effort we are able to put into maintaining them.

Tier I - All efforts are made to curate the gene structures and any other genetic or metabolic information. Only C. elegans is in this group.

Tier II - Efforts are made, where practical, to manually curate the gene structure and possibly some other genomic information.

Tier III - We will set up the genome on WormBase with any gene structures that the authors of this genome have predicted. No further curation efforts are made by the WormBase consortium.

Tier IV - Proposed tier for organisms with only transcriptome information and no coherent genome. There are no examples of this at present.

Genome

The Genome column in the table indicates whether the genome has been added to WormBase.

Gene

The Genes column in the table indicates whether gene structures have been added to WormBase.

The genome status

Species NCBI TaxonID Tier Genome Genes Origin Comments
Caenorhabditis briggsae 6228 II Yes Yes WashU [Sept 2010] New assembly from Erich Haag being worked on.
Caenorhabditis remanei 31234 II Yes Yes WashU
Caenorhabditis brenneri
(Species 4)
135651 II Yes Yes WashU
Caenorhabditis elegans strain N2 6239 I Yes Yes WashU/Sanger
Caenorhabditis elegans strain DR1035 6239 III Mark Blaxter status unclear
Caenorhabditis japonica 281617 II Yes Yes WashU
Caenorhabditis drosophilae 96641 III WashU [Sept 2010] being assembled
Caenorhabditis species 3 strain PS1010 9668 II Yes Yes CalTech Added to WormBase in release WS218.
Heterorhabditis bacteriophora 37862 III WashU
Pristionchus pacificus 54126 II Yes Yes WashU [21 June 2010] Christophe Dietrich says "he will switch to the new assembly which is not in Genbank but part of PubMed 20237107. Move the old gene predictions and corrections to new assembly. There is 454 data as well. New assemblies will be made as he has time."
Haemonchus contortus 6289 III Yes Yes Sanger Added to WormBase in release WS209.
Strongyloides ratti 34506 III Sanger [30 June 2010] Assembly due out in mid 2011. They have fosmid & BAC libraries. Have ~5000 contigs and ~99% of genome done. Have about 10,000 genes which is the expected number as it is half the size of C. elegans.
Meloidogyne hapla 6305 III Yes Yes NCSU hapla.org Added to WormBase in release WS204.
Meloidogyne incognita 6306 III Yes INRA Added to WormBase in release WS205. Genes are not yet available.
Brugia malayi 6279 III Yes Yes TIGR -> WashU/Sanger [Sept 2010] Currently using the old TIGR assembly. Waiting for WashU (did assembly) and Sanger (did gene models) to publish, then we will use the new assembly
Onchocerca volvulus 6282 III Sanger
Ascaris suum 6253 III Sanger
Globodera pallida 36090 III Sanger
Nippostrongylus brasiliensis 27835 III Sanger
Strongyloides ransomi 553534 III Sanger
Teladorsagia circumcincta 45464 III Sanger
Trichuris muris 70415 III Sanger
Trichinella spiralis 6334 III WashU [Sept 2010] Being assembled.


Phylogeny

Given my understanding of the current phylogenetic literature, the correct guide tree would be:

((((((((((C.briggsae,C.remanei),C.brenneri),C.elegans),C.japonica),(C.drosophila,C.species3)),(H.contortus,H.bacteriophora)),P.pacificus),S.ratti),(M.hapla,M.incognita)),B.malayi)

Tree3.png

See also