Data mining:WormMart:Example 3

Download the set of all RNAi experiments that resulted in an embryonic lethal (Emb) phenotype, and in which the target genes are classified as serine/threonine kinases.

• Start a new WormMart query and;
  • Select the latest database and the RNAi dataset
    

• Within the Filter section;
  • Under Phenotype, Enable the Limit to Phenotype Primary Name filter, and select the embryonic lethal option,
• Within the lower Dataset section;
  • For the Second Dataset select GO Term as we will use this dataset to filter for serine/threonone kinases,
  • Within the Go Term's Filter section, Enable the Limit to GO Term ID(s) filter, and enter GO:0004674 (protein serine/threonine kinase activity). 

• Within the RNAi Attribute section;
  • In the RNAi section, select RNAi WB ID,
  • In the Phenotype section, select Observed Phen Info (merged),
  • In the Inhibits Gene section, select Gene Info (merged),
  • In the Experiment section, select Author (merged)
  • The above selection is shown [HERE],
  • Click export to produce the results shown [HERE].

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