WBConfCall 2014.02.06-Agenda and Minutes

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Agenda

Plans for WS243

  • Topic curation for WS243 & WS244: Repsonse to Pathogens, Signaling in Innate Immunity
    • Take papers and genes from two WormBook chapters:
  1. Interactions with microbial pathogens (2005) - Creg Darby
  2. Signaling in the immune response (2006) - Jonathan J. Ewbank

Upcoming Species

  • Necator americanus <= WS242
  • Gene set for Meloidogyne incognita (finally).
  • Pristionchus exspectatus
  • Pristionchus pacificus <= waiting for ENA submission

Models schedule

  • Decide on WS243 upload date (Proposed Friday 28th March)
  • Models Tagging -2 weeks (14th March)
  • Models proposal deadline -3 weeks (7th March)

Not tied to a call.

Generating gene association files that conform to the GAF 2.0 format (Ranjana, Raymond)

  • Gene association files (GAFs) are generated by Hinxton for GO, phenotype and anatomy data, but they currently don't conform to the GAF 2.0 format which is the industry standard, and required for the ontology browser that Raymond and Juancarlos are working on.
gene_association         all good
anatomy_association column 6  => "WB_REF:WBPaperDDDDDDDDD"
                    column 9  => "A" for anatomy ontology ("D" for disease ontology).
                    column 12 => "gene"
                    column 13 => "taxon:DDDD"
phenotype_association    same as anatomy
                      
  • We need to generate a GAF for gene-disease data (Ranjana and Paul D can talk offline about this)

Oustanding issues

https://github.com/WormBase/website/issues/2361

I haven't found a satisfactory way to remap gene name changes across releases. If it's somewhere obvious I apologise in advance, but I've trawled through the ftp site plenty.
Thanks

WormMine:

https://github.com/WormBase/website/issues/2365

Hi, 

I have a list of a few hundred genes, and I want to retrieve all coding nucleotide sequences associated with each gene. This would be the equivalent of going to each gene's page in Wormbase, clicking on the link to go to the transcript page, and selecting "view spliced + UTR." 

This seems like it should be a straightforward thing to do via WormMine, but I can't seem to figure out how to do it. 

Thanks for your help!
Dan


https://github.com/WormBase/website/issues/2364

  How do I export coordinates for start & end bp and exons for genes via WormMine? 

Can I get coordinates for the latest gene models but translate them so that they work on genome build WS220?

My C elegans resequencing has been aligned to the WS220 build, is there any way of using the most up to date gene models whilst using my current files, or do I need to realign to a more up to date genome build?


Webteam WS241

Issues we are currently working on to go into production for WS241: https://github.com/WormBase/website/issues?direction=desc&milestone=16&page=1&sort=updated&state=open

Minutes

Plans for WS243

  • Chris : topic curation. Response to Pathogens, Signalling in Innate Immunity
    • will go ahead and spread it out over two releases
    • > 200 papers.
  • MH:
    • web presentation? need more connections
    • AC: asked to make issues when he sees things like this


Upcoming SPecies (MH)

EBI working on:

  • considering for upcoming releasese
  • Nacator americanus - WS242
  • M incognita - got in contact with ppl from this project. Will get new assembly in near future
  • P exspectatus
  • P pacificus - waiting for ena submission
  • AC: please test new species

Models Schedule

  • WS243 upload date: Friday March 28th
    • normal two months (since we're spreading topic over two releases)
    • Models Tagging -2 weeks (14th March)
    • Models proposal deadline -3 weeks (7th March)

Generating gene association files

  • Kevin - already did this

Outstanding issues

  • Chris will address WormMine issues

Open table

Parasite:

  • alexandra just started, working on this
  • web dev starting next month
  • hoping to release in the summer


Database meeting Toronto:

  • March 10-11 (mon/tues)
  • agenda is being worked on
  • caltech: paul s, raymond, juancarlos