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| Line 1: |
Line 1: |
| − | Relevant links
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| − | *[[Overview of molecule pages]]
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| − | **[[Molecule papers]]
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| − | **[[Example molecule pages]]
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| − | *[[Molecule model build]]
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| | | | |
| − | ----
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| − | ==Papers flagged for chemical==
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| − | {| {{table}} border=1
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| − | | align="center" style="background:#f0f0f0;"|'''WBPaperID'''
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| − | | align="center" style="background:#f0f0f0;"|'''Comment'''
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| − | |-
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| − | | 461||tetramisole
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| − | |-
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| − | | 464||Yes
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| − | |-
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| − | | 484||Yes
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| − | |-
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| − | | 493||enhanced sensitivity of flu-2 mutants to EMS
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| − | |-
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| − | | 536||pharmacological analysis of cell function (spermatozoan motility) not gene function
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| − | |-
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| − | | 1001||Vanadate, AMP-PNP, ATP-gamma-S. NEM, Triton X-100, Taxol, analysis on unknown motor protein
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| − | |-
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| − | | 1010||
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| − | |-
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| − | | 1524||forskolin, NaF, AlCl3, GTPgammaS, GppNHp, GDPbetaS, pertussis toxin, cholera toxin
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| − | |-
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| − | | 2029||campthothecin, berenil, trypanocidal drug, magnesium ion on DNA relaxation, and isolated topoisomerase, no gene product mentioned
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| − | |-
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| − | | 2116||
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| − | |-
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| − | | 3137||sodium arsenite, mercuric choride
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| − | |-
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| − | | 3150||ouabain
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| − | |-
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| − | | 13430||hematin, benzimidazole, Albendazole Diethylcarbamazine Fenbendazole Hematin Imidazole Ivermectin Levamisole Mebendazole Methimazole Morantel tartrate Oxibendazole Piperazine Pyrantel tartrate Thiabendazole: only tested in vitro on H. contortus GST activity.
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| − | |-
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| − | | 24940||aldicarb
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| − | |-
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| − | | 24950||diacetyl
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| − | |-
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| − | | 25017||fig 4
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| − | |-
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| − | | 25173||Fig 5, Fig 7.
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| − | |-
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| − | | 28357||yes
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| − | |-
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| − | | 28562||octopamine
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| − | |-
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| − | | 28879||serotonin
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| − | |-
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| − | | 28900||fig.3
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| − | |-
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| − | | 29114||yes
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| − | |-
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| − | | 29130||fig.3, fig.4
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| − | |-
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| − | | 30726||isoamyl alcohol
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| − | |-
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| − | | 30928||fig.2 d) Exogenous serotonin and fluoxetine suppress 100G-induced DAF- 16TGFP nuclear accumulation.
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| − | |-
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| − | | 31225||yes
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| − | |-
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| − | | 31321||Figure 3. High NaCl accelerates aging of C. elegans
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| − | |-
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| − | | 31336||nitrogen mustard
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| − | |-
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| − | | 31342||yes
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| − | |-
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| − | | 31419||yes
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| − | |-
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| − | | 31424||fig.7
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| − | |-
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| − | | 31427||vitamin E
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| − | |-
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| − | | 31428||yes
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| − | |-
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| − | | 31456||tunicamycin
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| − | |-
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| − | | 31464||yes
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| − | |-
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| − | | 31468||fig.3
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| − | |-
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| − | | 31474||yes
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| − | |-
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| − | | 31482||FUDR
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| − | |-
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| − | | 31483||mPyrazine
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| − | |-
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| − | | 31490||yes
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| − | |-
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| − | | 31509||yes
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| − | |-
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| − | | 31530||yes
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| − | |-
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| − | | 31535||yes
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| − | |-
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| − | | 31571||yes
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| − | |-
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| − | | 31593||yes
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| − | |-
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| − | | 31604||nicotine
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| − | |-
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| − | | 31626||yes
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| − | |-
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| − | | 31627||yes
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| − | |-
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| − | | 31644||yes
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| − | |-
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| − | | 31657||yes
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| − | |-
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| − | | 31667||yes
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| − | |-
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| − | | 31669||ethanol
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| − | |-
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| − | | 31672||yes
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| − | |-
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| − | | 31682||yes
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| − | |-
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| − | | 31683||yes
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| − | |-
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| − | | 31690||yes
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| − | |-
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| − | | 31694||yes
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| − | |-
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| − | | 31703||haem
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| − | |-
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| − | | 31810||yes
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| − | |-
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| − | | 31824||yes
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| − | |-
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| − | | 31834||yes
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| − | |-
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| − | | 31850||fluorathene
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| − | |-
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| − | | 31857||yes
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| − | |-
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| − | | 31866||yes
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| − | |-
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| − | | 31871||DHP
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| − | |-
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| − | | 31872||aldicarb
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| − | |-
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| − | | 31873||arsenite
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| − | |-
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| − | | 31882||8-Br-cGMP
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| − | |-
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| − | | 31895||Figure 4. Responses of wild-type (N2) and slo-1 mutant worms to aldicarb and levamisole
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| − | |-
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| − | | 31897||fig.4
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| − | |-
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| − | | 31915||yes
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| − | |-
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| − | | 31924||yes
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| − | |-
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| − | | 31939||table 2
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| − | |-
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| − | | 31941||paraquat
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| − | |-
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| − | | 31959||yes
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| − | |-
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| − | | 31977||imipramine
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| − | |-
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| − | | 31982||glutamate
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| − | |-
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| − | | 31991||Flavone (2-phenyl chromone)
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| − | |-
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| − | | 31992||NaCl
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| − | |-
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| − | | 31994||arsenite
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| − | |-
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| − | | 31996||fig.1
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| − | |-
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| − | | 31999||diltiazem
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| − | |-
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| − | | 32000||arecoline
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| − | |-
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| − | | 32007||levamisole
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| − | |-
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| − | | 32008||aldicarb
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| − | |-
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| − | | 32011||aldicarb
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| − | |-
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| − | | 32031||NaCl
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| − | |-
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| − | | 32033||yes
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| − | |-
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| − | | 32035||yes
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| − | |-
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| − | | 32050||yes
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| − | |-
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| − | | 32072||amiloride
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| − | |-
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| − | | 32077||C17ISO
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| − | |-
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| − | | 32079||Dextran-HCC
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| − | |-
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| − | | 32093||Quercetin
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| − | |-
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| − | | 32101||cadmium, chlorpyrifos, nickel, prochloraz, diuron
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| − | |-
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| − | | 32103||yes
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| − | |-
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| − | | 32125||imidacloprid, thiacloprid
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| − | |-
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| − | | 32131||yes
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| − | |-
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| − | | 32142||phosphine, FCCP (carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone), PCP (2,3,4,5,6pentachlorophenol), DNP (2,4-dinitrophenol), sodium azide
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| − | |-
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| − | | 32143||yes
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| − | |-
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| − | | 32181||Table S2. Activity of the ascarosides in Daf-c and Daf-d strain backgrounds in the dauer formation assay
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| − | |-
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| − | | 32192||tunicamycin
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| − | |-
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| − | | 32207||1NA-PP1
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| − | |-
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| − | | 32215||butanone, benzaldehyde
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| − | |-
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| − | | 32232||paraquat
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| − | |-
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| − | | 32237||paraquat
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| − | |-
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| − | | 32241||paraquat
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| − | |-
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| − | | 32243||ceramide
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| − | |-
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| − | | 32252||aldicarb
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| − | |-
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| − | | 32255||H2O2
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| − | |-
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| − | | 32259||3-methyladenine
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| − | |-
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| − | | 32266||metaboilte DA dafachronic acid, steroids
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| − | |-
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| − | | 32271||ethanol aldicarb
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| − | |-
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| − | | 32286||root exudate
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| − | |-
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| − | | 32295||Ethosuximide
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| − | |-
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| − | | 32319||NaCl and isoamyl alcohol (chemoattractants).
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| − | |-
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| − | | 32335||serotonin
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| − | |-
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| − | | 32336||benzaldehyde
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| − | |-
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| − | | 32358||aldicarb
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| − | |-
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| − | | 32359||ivermectin
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| − | |-
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| − | | 32366||levamisole, nicotine
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| − | |-
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| − | | 32390||flavonoid quercetin
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| − | |-
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| − | | 32427||volatile anesthetic, halothane
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| − | |-
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| − | | 32429||1-octanol
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| − | |-
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| − | | 32470||Species specificity of dauer pheromone extracts between elegans and Pristionchus. Response of Pristionchus and Strongyloides to different dafachronic acids.
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| − | |-
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| − | | 32475||mianserin methiothepin
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| − | |-
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| − | | 32478||levamisole
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| − | |-
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| − | | 32491||amino acids
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| − | |-
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| − | | 32494||AgNO3, CdCl2,CrCl2, CoCl2, CuSO4, HgCl2, MnCl2, NiSO4, Pb(NO3)2,and ZnCl2
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| − | |-
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| − | | 32508||chlorpyrifos oxon; cadmium chloride); hexachlorophene; neurotoxicants; chlorpyrifos, methyl mercury, chlordiazepoxide, tebuconazol; Cocaine; metals, ethanol, solvents, organophosphate; carbamate pesticides
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| − | |-
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| − | | 32517||Fig 1.The structures of the dauer pheromone components, ascaroside C6 (1), ascaroside C9 (2), ascaroside C3 (3), and the less active ascaroside C7 (4). Fig 2. The chemical structures of the long-chain ascarosides from conditioned medium extracts from long-term dhs-28 cultures. The structural assignment of long-chain ascaroside 17 is tentative
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| − | |-
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| − | | 32522||Sulfonamide CA inhibitors (CAIs) such as acetazolamide AZA, methazolamide MZA or ethoxzolamide EZA, many new sulfonamides (such as GUZ
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| − | |-
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| − | | 32878||NaN3, benzaldehyde
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| − | |-
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| − | | 32880||hydrogen peroxide
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| − | |-
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| − | | 32881||5-HT; Octanol, DiD
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| − | |-
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| − | | 32884||paraquat, juglone
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| − | |-
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| − | | 32886||dafachronic acids; Supp. New compounds reported in this study are: III, S-III, S-V, S-XV, S-XVI, S-XXII, XXIII, S-XXIII, XXIV, XXVII.
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| − | |-
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| − | | 32887||
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| − | |-
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| − | | 32888||dichlorvos,an organophosphorus insecticide, acetylcholinesterase, cadmium chloride
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| − | |-
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| − | | 32889||sulfonamides; CAIs; 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides possessing various 2-,3- or 4-substituted phenyl groups with methyl-, halogeno- and methoxy-functionalities, as well as the perfluorophenyl moiety; AZA and EZA
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| − | |-
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| − | | 32901||CO2
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| − | |-
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| − | | 32903||paraquat
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| − | |-
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| − | | 32918||Thus, (25R)-D7-dafachronic acid (2a) is one order of magnitude more active than (25R)-D4-dafachronic acid (1a). Similar to a previous study,5 little or no activity was detected with (25R)-cholestenoic acid (3a)
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| − | |-
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| − | | 32925||cycloheximide
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| − | |-
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| − | | 32932||resveratrol peptone
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| − | |-
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| − | | 32949||Paraquat, tunicamycin
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| − | |-
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| − | | 32956||These chemicals used on Pratylenchus penetrans: Acetic acid Propionic acid Isobutyric acid n-Butyric acid Isovaleric acid n-Valeric acid n-Caproic acid These chemicals used on C. elegans Acetic acid n-Caproic acid
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| − | |-
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| − | | 32958||Fe-exposure
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| − | |-
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| − | | 32968||tetramisole
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| − | |-
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| − | | 32989||The levels of superoxide radical (.0^2-), in both mitochondria and cytosol, are increased in sod-1(tm776) and sod-1(tm783) mutants.
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| − | |-
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| − | | 32997||dauer pheromone
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| − | |-
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| − | | 33002|| aldicarb levamisole
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| − | |-
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| − | | 33004||electrically evoked and light evoked pharyngeal cholinergic post synaptic potentials reduced in amplitude by nicotinic antagonists benzoquinonium chloride and d-tubocurarine. Effect dose dependent.
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| − | |-
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| − | | 33009||checked
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| − | |-
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| − | | 33024||chloramine-T (CHT), DTT, H^20^2: tested for effects on both KVS-1 activity in vitro and on chemotaxis in vivo.
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| − | |-
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| − | | 33037||dauer pheromone; 8-bromo-cGMP
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| − | |-
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| − | | 33040||paraquat, excess O^2
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| − | |-
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| − | | 33049||Carbamate, Aldicarb, Carbofuran, Oxamyl, Neostigmine, Eserine, Organophosphates, Fenomiphos, Ethoprop, Parathion, Paraoxon, Phorate, Terbufos, meta-chlorperbenzoic acid, m-CPBA, diotioate
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| − | |-
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| − | | 33051||identification of new daf-22 dependent dauer pheromone and mating pheromones ascr#7, ascr#8, and ascr#6.1
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| − | |-
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| − | | 33060||green tea polyphenol epigallocatechin gallate (EGCG) -
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| − | |-
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| − | | 33077||flavopiridol olomoucine II
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| − | |-
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| − | | 33086||hyperosmotic, sodium chloride, anoxia
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| − | |-
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| − | | 33094||PMA induces the pnlp-29::gfp transgene
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| − | |-
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| − | | 33099||dichlorvos fenamiphos organophosphates organophosphorous pesticides, neurotoxicant, mefloquine,
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| − | |-
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| − | | 33115||low oxygen, lactacystn
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| − | |-
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| − | | 33126||tunicamycin, glucose, deoxyglucose, sorbitol, glucose analog
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| − | |-
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| − | | 33130||D-ribose affect larval growth
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| − | |-
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| − | | 33158||Yes. Response to Diacetyl.
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| − | |-
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| − | | 33162||The uncoupler CCCP (carbonylcyanide- 3-chlorophenylhydrazone) extends lifespan.
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| − | |-
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| − | | 33166||dietary zinc
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| − | |-
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| − | | 33168||Antipsychotic drugs, cyclosporin A
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| − | |-
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| − | | 33189||Iron, PQS, PQS+Fe3
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| − | |-
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| − | | 33433||copper
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| − | |-
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| − | | 33441||Pb, Hg, Cd, and Cr metals CdCl2, CrCl2, HgCl2, and Pb(NO3)2 in solution were used here: 2.5M, 50M, and 100M.
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| − | |-
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| − | | 33448||Catechin Hydrogen peroxide catechin hydrate
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| − | |-
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| − | | 33456||8-bromo cGMP, paraquat, vinpocetine, zaprinast, EHNA (erythro-9-[2-hydroxy-3-nonyl] adenine)
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| − | |-
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| − | | 34686||CdCl2, CrCl2, HgCl2, Pb(NO3)2
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| − | |-
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| − | | 34687||Screened ~54,000 chemicals from various libraries: Bioactives, natural product extracts, Analyticon purified natural product compounds, Diversity-oriented synthesis, ChemBridge kinases, ChemDiv, TimTec, MayBridge, ChemBridge. note: screened on glp-4(bn2);sek-1(km4) mutant worms Anti-infective hits that cure C. elegans of an E. faecalis infection at a concentration lower than the in vitro MIC with E. faecalis are grouped into 6 structural classes (representative structures shown).
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| − | |-
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| − | | 34688||Bis-[4-methoxy-3- [3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2Hpyrazolo[ 3,4-d]thiazol-5-yl]phenyl]methanes nematicidal activity
| |
| − | |-
| |
| − | | 34706||Exposure to examined metals caused severe lethality toxicities in L1- and L2-larvae...
| |
| − | |-
| |
| − | | 34717||fig 1, 40um juglone caused a significant increase in lifespan
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| − | |-
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| − | | 34757||juglone, paraquat
| |
| − | |-
| |
| − | | 34758||Rotenone, paraquat
| |
| − | |-
| |
| − | | 34766||Cry5B toxin
| |
| − | |-
| |
| − | | 35074||tribendimidine, levamisole, pyrantel
| |
| − | |-
| |
| − | | 35082||drugs: muscimol and serotonin
| |
| − | |-
| |
| − | | 35083||myxothiazol, FCCP
| |
| − | |-
| |
| − | | 35098||Rib1P, 2-deoxy-a-d-ribose 1-phosphate (dRib1P), uridine, UMP, UDP, UTP, ATP, 2-deoxyuridine, 5-FU, 5dFUR, orotidine 5¬¢-phosphate, PPRP and 5-FU
| |
| − | |-
| |
| − | | 35114||Pcm-1 mutant dauer larvae exposed to juglone develop into adults with a defect in egg-laying (Egl). Pcm-1 mutant eggs exposed to the oxidizing agents paraquat, homocysteine, and homocysteine thiolactone undergo a developmental delay more pronounced than that observed in wild-type animals. Pcm-1 mutant eggs exposed to homocysteine develop in to adults with a defect in egg-laying.
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| − | |-
| |
| − | | 35522||2-nonanone
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| − | |-
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| − | |}
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