Difference between revisions of "How WormBase writes a concise description"
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==Writing a concise description for a C. elegans gene== | ==Writing a concise description for a C. elegans gene== | ||
− | + | Curators as a general rule make sure that the following key facts are captured in a concise description, when this information is available in published literature, please do not use information from meeting abstracts, Worm Breeder Gazette articles, personal observations, etc.: | |
*Molecular identity | *Molecular identity | ||
Line 11: | Line 11: | ||
*Sub cellular localization | *Sub cellular localization | ||
− | + | So, the template for a concise description will look something like: | |
'''Molecular identity''' | '''Molecular identity''' | ||
<Gene> encodes .....; | <Gene> encodes .....; | ||
Line 19: | Line 19: | ||
<Gene> is <required, functions, regulates, is involved in, is part of> .....; | <Gene> is <required, functions, regulates, is involved in, is part of> .....; | ||
'''Genetic interaction with respect to Process or Pathway''' | '''Genetic interaction with respect to Process or Pathway''' | ||
− | <Gene> interacts genetically with ..... in <Process, Pathway>; | + | <Gene> interacts genetically with <gene1, gene2>..... in <Process, Pathway>; |
'''Physical interaction''' | '''Physical interaction''' | ||
− | <Protein> physically interacts < | + | <Protein> physically interacts with <protein, DNA, RNA).......; |
'''Molecular Function''' | '''Molecular Function''' | ||
− | <Protein> has | + | <Protein> has ……… activity in <in vitro, in vivo> assays; |
'''Tissue Expression''' | '''Tissue Expression''' | ||
<Gene/Protein> is expressed in …………and expression in ......is (positively, negatively) | <Gene/Protein> is expressed in …………and expression in ......is (positively, negatively) | ||
regulated by .......; | regulated by .......; | ||
− | ''' | + | '''Sub-cellular localization''' |
− | <Protein> is localized to <sub-cellular component> or .......and expression in | + | <Protein> is localized to <sub-cellular component> or .......and expression in <sub-cellular component> is |
− | + | <positively, negatively> regulated by ........ |
Revision as of 18:57, 2 April 2013
Writing a concise description for a C. elegans gene
Curators as a general rule make sure that the following key facts are captured in a concise description, when this information is available in published literature, please do not use information from meeting abstracts, Worm Breeder Gazette articles, personal observations, etc.:
- Molecular identity
- Orthology
- Process/Pathway
- Genetic interactions
- Physical interactions
- Function/Molecular Activity
- Tissue Expression
- Sub cellular localization
So, the template for a concise description will look something like:
Molecular identity <Gene> encodes .....; Orthology/Similarity <Gene> is <orthologous, similar) to .....; Process/Pathway <Gene> is <required, functions, regulates, is involved in, is part of> .....; Genetic interaction with respect to Process or Pathway <Gene> interacts genetically with <gene1, gene2>..... in <Process, Pathway>; Physical interaction <Protein> physically interacts with <protein, DNA, RNA).......; Molecular Function <Protein> has ……… activity in <in vitro, in vivo> assays; Tissue Expression <Gene/Protein> is expressed in …………and expression in ......is (positively, negatively) regulated by .......; Sub-cellular localization <Protein> is localized to <sub-cellular component> or .......and expression in <sub-cellular component> is <positively, negatively> regulated by ........