Difference between revisions of "Balancers"
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| References | | References | ||
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− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/eDp6 eDp6(III;f)] |
| '''Summary:''' Free duplication, moderately well characterized, not observed to recombine with normal homologs. Very effective balancer for right portion of LG III from right end through tra-1 and vab-7. | | '''Summary:''' Free duplication, moderately well characterized, not observed to recombine with normal homologs. Very effective balancer for right portion of LG III from right end through tra-1 and vab-7. | ||
'''Origin/Mutagen:''' Acetaldehyde mutagenesis. | '''Origin/Mutagen:''' Acetaldehyde mutagenesis. | ||
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| Hodgkin, J. (1980; 1987); Hunter, C.P., and Wood, W.B., 1990. | | Hodgkin, J. (1980; 1987); Hunter, C.P., and Wood, W.B., 1990. | ||
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− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/eT1?query=et1 eT1(III;V)] |
| '''Summary:''' Reciprocal translocation, well characterized, extremely stable. Very effective balancer for left portion of LG V from left end through unc-23, and right portion of LG III from right end to unc-36. eT1(III) is LG V (left) translocated to LG III (left), disjoins from normal LG III. eT1(V) is LG III (right) translocated to LG V (right), disjoins from normal LG V. Zhao et al. reports the sequence of the physical breakpoint of eT1 on chromosome V (the breakpoint of eT1 chromosome III is in the unc-36 gene). | | '''Summary:''' Reciprocal translocation, well characterized, extremely stable. Very effective balancer for left portion of LG V from left end through unc-23, and right portion of LG III from right end to unc-36. eT1(III) is LG V (left) translocated to LG III (left), disjoins from normal LG III. eT1(V) is LG III (right) translocated to LG V (right), disjoins from normal LG V. Zhao et al. reports the sequence of the physical breakpoint of eT1 on chromosome V (the breakpoint of eT1 chromosome III is in the unc-36 gene). | ||
'''Origin/Mutagen:''' 32P mutagenesis of N2. | '''Origin/Mutagen:''' 32P mutagenesis of N2. | ||
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|Rosenbluth, R.E., and Baillie, D.L., 1981; Rosenbluth, R.E., Cuddeford, C., and Baillie, D.L. (1983; 1985); McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Nelson, G.A., Schubert, W.W., Marshall, T.M., Benton, E.R., and Benton, E.V., 1989; Adames, K.A., Gawne, J., Wicky, C., Muller, F., and Rose, A.M., 1998. Zhao, Y., Lai, K., Cheung, I., Youds, J., Tarailo, M., Tarailo, S., and Rose, A.M.,2006. | |Rosenbluth, R.E., and Baillie, D.L., 1981; Rosenbluth, R.E., Cuddeford, C., and Baillie, D.L. (1983; 1985); McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Nelson, G.A., Schubert, W.W., Marshall, T.M., Benton, E.R., and Benton, E.V., 1989; Adames, K.A., Gawne, J., Wicky, C., Muller, F., and Rose, A.M., 1998. Zhao, Y., Lai, K., Cheung, I., Youds, J., Tarailo, M., Tarailo, S., and Rose, A.M.,2006. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/hIn1?query=hin1 hIn1(I)] |
| '''Summary:''' Inversion, well characterized, very stable. Very effective balancer for right portion of LG I from unc-75 through unc-54. Extreme right end of chromosome apparently not balanced. | | '''Summary:''' Inversion, well characterized, very stable. Very effective balancer for right portion of LG I from unc-75 through unc-54. Extreme right end of chromosome apparently not balanced. | ||
'''Origin/Mutagen:''' Gamma irradiation of N2 males. | '''Origin/Mutagen:''' Gamma irradiation of N2 males. | ||
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| Lee, J., Jongeward, G.D., and Sternberg, P.W., 1994; Zetka, M.C., and Rose, A.M., 1992. | | Lee, J., Jongeward, G.D., and Sternberg, P.W., 1994; Zetka, M.C., and Rose, A.M., 1992. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/hT1 hT1(I;V)] |
| '''Summary:''' Reciprocal translocation, well characterized, very stable. Very effective balancer for left portion of LG I from the left end through let-80, and the left portion of LG V from the left end through dpy-11. hT1(I) is LG V (left) translocated to LG I (right), disjoins from normal LG I. hT1(V) is LG I (left) translocated to LG V (right), disjoins from normal LG V. | | '''Summary:''' Reciprocal translocation, well characterized, very stable. Very effective balancer for left portion of LG I from the left end through let-80, and the left portion of LG V from the left end through dpy-11. hT1(I) is LG V (left) translocated to LG I (right), disjoins from normal LG I. hT1(V) is LG I (left) translocated to LG V (right), disjoins from normal LG V. | ||
'''Origin/Mutagen:''' Gamma irradiation of unc-23 + / + unc-42 males. | '''Origin/Mutagen:''' Gamma irradiation of unc-23 + / + unc-42 males. | ||
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|McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Howell, A.M., and Rose, A.M., 1990. | |McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Howell, A.M., and Rose, A.M., 1990. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/hT2 hT2(I;III)] |
| '''Summary:''' Reciprocal translocation, well characterized, stable. Effective balancer for left portion of LG I from left end through unc-101, and right portion of LG III from right end through dpy-17. hT2(I) is LG III (right) translocated to LG I (right), disjoins from normal LG I. hT2(III) is LG I (left) translocated to LG III (left), disjoins from normal LG III. | | '''Summary:''' Reciprocal translocation, well characterized, stable. Effective balancer for left portion of LG I from left end through unc-101, and right portion of LG III from right end through dpy-17. hT2(I) is LG III (right) translocated to LG I (right), disjoins from normal LG I. hT2(III) is LG I (left) translocated to LG III (left), disjoins from normal LG III. | ||
'''Origin/Mutagen:''' Gamma irradiation of bli-4(e937)I males. | '''Origin/Mutagen:''' Gamma irradiation of bli-4(e937)I males. | ||
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| McKim, K.S., Peters, K., and Rose, A.M., 1993; J. Kimble, pers. comm. | | McKim, K.S., Peters, K., and Rose, A.M., 1993; J. Kimble, pers. comm. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/ht3 hT3(I;X)] |
| '''Summary:''' Translocation (rigorous proof of reciprocity lacking), moderately well characterized, very stable. Very effective balancer for left portion of LG I from left end to around let-363, and the right portion of LG X from the right end to between dpy-7 and unc-3. hT3(I), which disjoins from normal LG I, is probably LG X (right) translocated to LG I (right). hT3(X),which disjoins from normal LG X, is probably LG I (left) translocated to LG X (left). | | '''Summary:''' Translocation (rigorous proof of reciprocity lacking), moderately well characterized, very stable. Very effective balancer for left portion of LG I from left end to around let-363, and the right portion of LG X from the right end to between dpy-7 and unc-3. hT3(I), which disjoins from normal LG I, is probably LG X (right) translocated to LG I (right). hT3(X),which disjoins from normal LG X, is probably LG I (left) translocated to LG X (left). | ||
'''Origin/Mutagen:''' Gamma irradiation mutagenesis of dpy-5(e61) unc-29(e403)/hT2[dpy-18(h662)] I; +/hT2[bli-4(e937)] III. Isolated as a lethal mutation balanced by hT2, now maintained as a homozygote balanced by szDp1. | '''Origin/Mutagen:''' Gamma irradiation mutagenesis of dpy-5(e61) unc-29(e403)/hT2[dpy-18(h662)] I; +/hT2[bli-4(e937)] III. Isolated as a lethal mutation balanced by hT2, now maintained as a homozygote balanced by szDp1. | ||
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| McKim, K.S., Peters, K., and Rose, A.M., 1993. | | McKim, K.S., Peters, K., and Rose, A.M., 1993. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mIn1 mIn1(II)] |
| '''Summary:''' Inversion, well characterized, very stable. Very effective balancer for center portion of LG II from lin-31 through rol-1. | | '''Summary:''' Inversion, well characterized, very stable. Very effective balancer for center portion of LG II from lin-31 through rol-1. | ||
'''Origin/Mutagen:'''Gamma irradiation of dpy-10(e128)/unc-85(e1414) rol-1(e91)II. | '''Origin/Mutagen:'''Gamma irradiation of dpy-10(e128)/unc-85(e1414) rol-1(e91)II. | ||
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| Edgley, M.L., and Riddle, D.L., 2001. | | Edgley, M.L., and Riddle, D.L., 2001. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mT1 mT1(II;III)] |
| '''Summary:''' Reciprocal translocation, well characterized, very stable. Very effective balancer for right portion of LG II from the right end through dpy-10, and the right portion of LG III from the right end to between daf-2 and unc-93. mT1(II) is probably LGII (right) translocated to LG III (left), disjoins from normal LG III. mT1(III) is probably LG III (right) translocated to LG II (left), disjoins from normal LG II. | | '''Summary:''' Reciprocal translocation, well characterized, very stable. Very effective balancer for right portion of LG II from the right end through dpy-10, and the right portion of LG III from the right end to between daf-2 and unc-93. mT1(II) is probably LGII (right) translocated to LG III (left), disjoins from normal LG III. mT1(III) is probably LG III (right) translocated to LG II (left), disjoins from normal LG II. | ||
'''Origin/Mutagen:''' Gamma irradiation of dpy-10(e128)/unc-85(e1414) rol-1(e91) II. | '''Origin/Mutagen:''' Gamma irradiation of dpy-10(e128)/unc-85(e1414) rol-1(e91) II. | ||
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| Edgley, M.L., and Riddle, D.L., 2001. | | Edgley, M.L., and Riddle, D.L., 2001. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mnC1 mnC1(II)] |
| '''Summary:''' Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for right portion of LG II from around dpy-10 to around unc-52. | | '''Summary:''' Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for right portion of LG II from around dpy-10 to around unc-52. | ||
'''Origin/Mutagen:''' X-ray mutagenesis of unc-4/dpy-10 unc-52. | '''Origin/Mutagen:''' X-ray mutagenesis of unc-4/dpy-10 unc-52. | ||
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| Herman, R.K., 1978; Sigurdson, D.C., Spanier, G.J., and Herman, R.K., 1984. | | Herman, R.K., 1978; Sigurdson, D.C., Spanier, G.J., and Herman, R.K., 1984. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mnDp1 mnDp1(X;V)] |
|'''Summary:''' Translocated duplication, well characterized, does not recombine with normal homologues. Very effective balancer for right portion of LG X from right end through let-4. | |'''Summary:''' Translocated duplication, well characterized, does not recombine with normal homologues. Very effective balancer for right portion of LG X from right end through let-4. | ||
'''Origin/Mutagen:''' ~7500-R X-ray mutagenesis of N2 males. | '''Origin/Mutagen:''' ~7500-R X-ray mutagenesis of N2 males. | ||
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| Herman, R.K., Albertson, D.G., and Brenner, S., 1976; Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Meneely P.M., and Herman, R.K., 1981. | | Herman, R.K., Albertson, D.G., and Brenner, S., 1976; Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Meneely P.M., and Herman, R.K., 1981. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mnDp3 mnDp3(X;f)] |
|'''Summary:''' Free duplication, well characterized, does not recombine with normal LG X. Effective balancer for right portion of LG X from around the right end through unc-9. | |'''Summary:''' Free duplication, well characterized, does not recombine with normal LG X. Effective balancer for right portion of LG X from around the right end through unc-9. | ||
'''Origin/Mutagen:''' ~7500-R X-ray mutagenesis of N2 males. | '''Origin/Mutagen:''' ~7500-R X-ray mutagenesis of N2 males. | ||
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| Herman, R.K., Albertson, D.G., and Brenner, S., 1976; Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Herman, R.K., 1984. | | Herman, R.K., Albertson, D.G., and Brenner, S., 1976; Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Herman, R.K., 1984. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mnDp10 mnDp10(X;I)] |
|'''Summary:''' Translocated duplication, well characterized, does not recombine with normal LG X. Effective balancer for right portion of LG X from around the right end through lin-2. | |'''Summary:''' Translocated duplication, well characterized, does not recombine with normal LG X. Effective balancer for right portion of LG X from around the right end through lin-2. | ||
'''Origin/Mutagen:''' ~7500-R X-ray mutagenesis of N2 males. | '''Origin/Mutagen:''' ~7500-R X-ray mutagenesis of N2 males. | ||
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| Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Meneely P.M., and Herman, R.K., 1981. | | Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Meneely P.M., and Herman, R.K., 1981. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mnDp33 mnDp33(X;IV)] |
|'''Summary:''' Translocated duplication, well characterized, does not recombine with normal X. Effective balancer for small region of left portion of LG X, from lin-18 to osm-5 (inclusive). | |'''Summary:''' Translocated duplication, well characterized, does not recombine with normal X. Effective balancer for small region of left portion of LG X, from lin-18 to osm-5 (inclusive). | ||
'''Origin/Mutagen:''' ~7500 R X-ray mutagenesis of N2 males. | '''Origin/Mutagen:''' ~7500 R X-ray mutagenesis of N2 males. | ||
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| Herman, R.K., Madl, J.E., and Kari, C.K., 1979. | | Herman, R.K., Madl, J.E., and Kari, C.K., 1979. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mnDp34 mnDp34(II)] |
|'''Summary:''' mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53. | |'''Summary:''' mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53. | ||
'''Origin/Mutagen''' ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120). | '''Origin/Mutagen''' ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120). | ||
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| Herman, R.K., Madl, J.E., and Kari, C.K., 1979. | | Herman, R.K., Madl, J.E., and Kari, C.K., 1979. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mnDp35 mnDp35(II)] |
|'''Summary:''' mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53. | |'''Summary:''' mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53. | ||
Origin:''' ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120). | Origin:''' ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120). | ||
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| Herman, R.K., Madl, J.E., and Kari, C.K., 1979. | | Herman, R.K., Madl, J.E., and Kari, C.K., 1979. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/mnDp36 mnDp36(II)] |
|'''Summary:''' mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53. | |'''Summary:''' mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53. | ||
'''Origin/Mutagen:''' ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120). | '''Origin/Mutagen:''' ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120). | ||
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| Herman, R.K., Madl, J.E., and Kari, C.K., 1979. | | Herman, R.K., Madl, J.E., and Kari, C.K., 1979. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/nT1 nT1(IV;V)] |
|'''Summary:''' Translocation, moderately well characterized, very stable. Very effective balancer for right portion of LG IV from right end through unc-17, and for left portion of LG V from left end through unc-76. | |'''Summary:''' Translocation, moderately well characterized, very stable. Very effective balancer for right portion of LG IV from right end through unc-17, and for left portion of LG V from left end through unc-76. | ||
'''Origin/Mutagen:''' Spontaneous. | '''Origin/Mutagen:''' Spontaneous. | ||
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|Ferguson, E.L., and Horvitz, H.R., 1985; Clark, D.V., Rogalski, T.M., Donati, L.M., and Baillie, D.L., 1988; Rogalski, T.M., and Riddle, D.L., 1988; J. Kimble, pers. comm. | |Ferguson, E.L., and Horvitz, H.R., 1985; Clark, D.V., Rogalski, T.M., Donati, L.M., and Baillie, D.L., 1988; Rogalski, T.M., and Riddle, D.L., 1988; J. Kimble, pers. comm. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/qC1 qC1(III)] |
|'''Summary:''' Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for the left portion of LG III from tra-1 to at least dpy-1. | |'''Summary:''' Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for the left portion of LG III from tra-1 to at least dpy-1. | ||
'''Origin/Mutagen:''' 7200-R gamma-irradiation mutagenesis of unc-32(e189)/dpy-19(e1259). | '''Origin/Mutagen:''' 7200-R gamma-irradiation mutagenesis of unc-32(e189)/dpy-19(e1259). | ||
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| Austin, J., and Kimble, J., 1989; J. Austin, E. Goodwin, and J. Kimble, pers. comm.; Ha and Baillie, unpublished results. | | Austin, J., and Kimble, J., 1989; J. Austin, E. Goodwin, and J. Kimble, pers. comm.; Ha and Baillie, unpublished results. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/sC1 sC1(III)] |
|'''Summary:''' Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for an approximately 15-mu portion of LG III from around unc-45 to near daf-2. | |'''Summary:''' Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for an approximately 15-mu portion of LG III from around unc-45 to near daf-2. | ||
'''Origin/Mutagen:''' 2000-R gamma-irradiation mutagenesis of N2 males. | '''Origin/Mutagen:''' 2000-R gamma-irradiation mutagenesis of N2 males. | ||
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| Stewart and Baillie, unpublished results. | | Stewart and Baillie, unpublished results. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/sC4 sC4(V)] |
|'''Summary:''' Dominant crossover suppressor, uncharacterized with regard to structure, moderately stable. Balances right portion of LG V from rol-9 to unc-76. | |'''Summary:''' Dominant crossover suppressor, uncharacterized with regard to structure, moderately stable. Balances right portion of LG V from rol-9 to unc-76. | ||
'''Origin/Mutagen:''' 2000-R gamma-irradiation mutagenesis of dpy-21/unc-76 rol-9. | '''Origin/Mutagen:''' 2000-R gamma-irradiation mutagenesis of dpy-21/unc-76 rol-9. | ||
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| Stewart and Baillie, unpublished results. | | Stewart and Baillie, unpublished results. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/sDp2 sDp2(I;f)] |
|'''Summary:''' Free duplication, well characterized, does not recombine with normal homologues. Very effective balancer for the left portion of LG I from the left end through unc-15 (just left of unc-13). | |'''Summary:''' Free duplication, well characterized, does not recombine with normal homologues. Very effective balancer for the left portion of LG I from the left end through unc-15 (just left of unc-13). | ||
'''Origin/Mutagen:''' 7500-R gamma-irradiation mutagenesis of N2 males. | '''Origin/Mutagen:''' 7500-R gamma-irradiation mutagenesis of N2 males. | ||
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| Rose, A.M., Baillie, D.L., and Curran, J., 1984; Howell, A.M., Gilmour, S.G., Mancebo, R.A., and Rose, A.M., 1987; Howell, A.M., and Rose, A.M., 1990; McKim, K.S., and Rose, A.M., 1990; McKim, K.S., Starr, T., and Rose, A.M., 1992; McKim, K.S., Peters, K., and Rose, A.M., 1993. | | Rose, A.M., Baillie, D.L., and Curran, J., 1984; Howell, A.M., Gilmour, S.G., Mancebo, R.A., and Rose, A.M., 1987; Howell, A.M., and Rose, A.M., 1990; McKim, K.S., and Rose, A.M., 1990; McKim, K.S., Starr, T., and Rose, A.M., 1992; McKim, K.S., Peters, K., and Rose, A.M., 1993. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/sDp3 sDp3(III;f)] |
|'''Summary:''' Free duplication, well characterized, does not recombine with normal homologues. Very effective balancer for left portion of LG III from around unc-86 through at least dpy-1 (does not extend to unc-45). | |'''Summary:''' Free duplication, well characterized, does not recombine with normal homologues. Very effective balancer for left portion of LG III from around unc-86 through at least dpy-1 (does not extend to unc-45). | ||
'''Origin/Mutagen:''' 1500-R gamma-irradiation mutagenesis of dpy-18/eT1 III; unc-46/ eT1 V. | '''Origin/Mutagen:''' 1500-R gamma-irradiation mutagenesis of dpy-18/eT1 III; unc-46/ eT1 V. | ||
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|Rosenbluth, R.E., Cuddeford, C., and Baillie, D.L., 1985. | |Rosenbluth, R.E., Cuddeford, C., and Baillie, D.L., 1985. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/stDp2 stDp2(X;II)] |
|'''Summary:''' Translocated duplication, moderately well characterized, not observed to recombine with normal LG X. Very effective balancer for small region in the center of LG X, from around unc-58 to around unc-6. | |'''Summary:''' Translocated duplication, moderately well characterized, not observed to recombine with normal LG X. Very effective balancer for small region in the center of LG X, from around unc-58 to around unc-6. | ||
'''Recommended use:''' General balancing, strain construction, strain maintenance. | '''Recommended use:''' General balancing, strain construction, strain maintenance. | ||
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| Meneely, P.M. and Wood, W.B., 1984. | | Meneely, P.M. and Wood, W.B., 1984. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/szDp1 szDp1(I;X;f)] |
|'''Summary:''' Complex free duplication, well characterized, does not recombine with normal LG I. Very effective balancer for the left portion of LG I from the left end through unc-13. Consists of one half-translocation [szT1(X)] from szT1 maintained in addition to a normal chromosome complement. | |'''Summary:''' Complex free duplication, well characterized, does not recombine with normal LG I. Very effective balancer for the left portion of LG I from the left end through unc-13. Consists of one half-translocation [szT1(X)] from szT1 maintained in addition to a normal chromosome complement. | ||
'''Origin/Mutagen:''' Exceptional Unc-3 segregant from dpy-5/szT1[lon-2] I; unc-3/szT1 X. | '''Origin/Mutagen:''' Exceptional Unc-3 segregant from dpy-5/szT1[lon-2] I; unc-3/szT1 X. | ||
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| McKim, K.S., Howell, A.M., and Rose, A.M., 1988; McKim, K.S., Starr, T., and Rose, A.M., 1992; McKim, K.S., Peters, K., and Rose, A.M., 1993; McKim, K.S., and Rose, A.M., 1990. | | McKim, K.S., Howell, A.M., and Rose, A.M., 1988; McKim, K.S., Starr, T., and Rose, A.M., 1992; McKim, K.S., Peters, K., and Rose, A.M., 1993; McKim, K.S., and Rose, A.M., 1990. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/szT1 szT1(I;X)] |
|'''Summary:''' Reciprocal translocation, well characterized, very stable. Effective balancer for left portion of LG I through unc-13, nearly all of LG X from right end to around dpy-3. szT1(I) is large segment of LG X (right) translocated to LG I, disjoins from normal LG I. szT1(X) is LG I (left) translocated to fragment of LG X (left), disjoins from normal LG X. | |'''Summary:''' Reciprocal translocation, well characterized, very stable. Effective balancer for left portion of LG I through unc-13, nearly all of LG X from right end to around dpy-3. szT1(I) is large segment of LG X (right) translocated to LG I, disjoins from normal LG I. szT1(X) is LG I (left) translocated to fragment of LG X (left), disjoins from normal LG X. | ||
'''Origin/Mutagen:''' 7000-R gamma-ray mutagenesis of lon-2(e678)/dpy-8(e1321) unc-3(e151)hermaphrodites. | '''Origin/Mutagen:''' 7000-R gamma-ray mutagenesis of lon-2(e678)/dpy-8(e1321) unc-3(e151)hermaphrodites. | ||
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| Fodor, A., and Deak, P., 1985; McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Howell, A.M., and Rose, A.M., 1990; McKim, K.S., and Rose, A.M., 1990. | | Fodor, A., and Deak, P., 1985; McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Howell, A.M., and Rose, A.M., 1990; McKim, K.S., and Rose, A.M., 1990. | ||
|- | |- | ||
− | | [http://www.wormbase.org/ | + | | [http://www.wormbase.org/species/all/rearrangement/yDp1 yDp1(IV;V;f)] |
|'''Summary:''' Complex free duplication, moderately well characterized, not observed to recombine with either normal homologue. Very effective balancer for right portion of LG IV from around dpy-4 to around unc-22, and left portion of LG V from around unc-34 through yDp1. | |'''Summary:''' Complex free duplication, moderately well characterized, not observed to recombine with either normal homologue. Very effective balancer for right portion of LG IV from around dpy-4 to around unc-22, and left portion of LG V from around unc-34 through yDp1. | ||
'''Origin/Mutagen:''' EMS mutagenesis of unc-22(s7) dpy-26(n199)IV/nT1[unc(n754) let](IV;V). | '''Origin/Mutagen:''' EMS mutagenesis of unc-22(s7) dpy-26(n199)IV/nT1[unc(n754) let](IV;V). |
Revision as of 08:32, 6 September 2013
The following table of Balancers has been adapted from the WormBook Chapter Genetic Balancers by Mark L. Edgley, David L. Baillie,2, Donald L. Riddle, and Ann M. Rose.
Rearrangement | Descriptions | References |
eDp6(III;f) | Summary: Free duplication, moderately well characterized, not observed to recombine with normal homologs. Very effective balancer for right portion of LG III from right end through tra-1 and vab-7.
Origin/Mutagen: Acetaldehyde mutagenesis.
|
Hodgkin, J. (1980; 1987); Hunter, C.P., and Wood, W.B., 1990. |
eT1(III;V) | Summary: Reciprocal translocation, well characterized, extremely stable. Very effective balancer for left portion of LG V from left end through unc-23, and right portion of LG III from right end to unc-36. eT1(III) is LG V (left) translocated to LG III (left), disjoins from normal LG III. eT1(V) is LG III (right) translocated to LG V (right), disjoins from normal LG V. Zhao et al. reports the sequence of the physical breakpoint of eT1 on chromosome V (the breakpoint of eT1 chromosome III is in the unc-36 gene).
Origin/Mutagen: 32P mutagenesis of N2.
|
Rosenbluth, R.E., and Baillie, D.L., 1981; Rosenbluth, R.E., Cuddeford, C., and Baillie, D.L. (1983; 1985); McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Nelson, G.A., Schubert, W.W., Marshall, T.M., Benton, E.R., and Benton, E.V., 1989; Adames, K.A., Gawne, J., Wicky, C., Muller, F., and Rose, A.M., 1998. Zhao, Y., Lai, K., Cheung, I., Youds, J., Tarailo, M., Tarailo, S., and Rose, A.M.,2006. |
hIn1(I) | Summary: Inversion, well characterized, very stable. Very effective balancer for right portion of LG I from unc-75 through unc-54. Extreme right end of chromosome apparently not balanced.
Origin/Mutagen: Gamma irradiation of N2 males.
|
Lee, J., Jongeward, G.D., and Sternberg, P.W., 1994; Zetka, M.C., and Rose, A.M., 1992. |
hT1(I;V) | Summary: Reciprocal translocation, well characterized, very stable. Very effective balancer for left portion of LG I from the left end through let-80, and the left portion of LG V from the left end through dpy-11. hT1(I) is LG V (left) translocated to LG I (right), disjoins from normal LG I. hT1(V) is LG I (left) translocated to LG V (right), disjoins from normal LG V.
Origin/Mutagen: Gamma irradiation of unc-23 + / + unc-42 males.
|
McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Howell, A.M., and Rose, A.M., 1990. |
hT2(I;III) | Summary: Reciprocal translocation, well characterized, stable. Effective balancer for left portion of LG I from left end through unc-101, and right portion of LG III from right end through dpy-17. hT2(I) is LG III (right) translocated to LG I (right), disjoins from normal LG I. hT2(III) is LG I (left) translocated to LG III (left), disjoins from normal LG III.
Origin/Mutagen: Gamma irradiation of bli-4(e937)I males.
|
McKim, K.S., Peters, K., and Rose, A.M., 1993; J. Kimble, pers. comm. |
hT3(I;X) | Summary: Translocation (rigorous proof of reciprocity lacking), moderately well characterized, very stable. Very effective balancer for left portion of LG I from left end to around let-363, and the right portion of LG X from the right end to between dpy-7 and unc-3. hT3(I), which disjoins from normal LG I, is probably LG X (right) translocated to LG I (right). hT3(X),which disjoins from normal LG X, is probably LG I (left) translocated to LG X (left).
Origin/Mutagen: Gamma irradiation mutagenesis of dpy-5(e61) unc-29(e403)/hT2[dpy-18(h662)] I; +/hT2[bli-4(e937)] III. Isolated as a lethal mutation balanced by hT2, now maintained as a homozygote balanced by szDp1.
|
McKim, K.S., Peters, K., and Rose, A.M., 1993. |
mIn1(II) | Summary: Inversion, well characterized, very stable. Very effective balancer for center portion of LG II from lin-31 through rol-1.
Origin/Mutagen:Gamma irradiation of dpy-10(e128)/unc-85(e1414) rol-1(e91)II.
|
Edgley, M.L., and Riddle, D.L., 2001. |
mT1(II;III) | Summary: Reciprocal translocation, well characterized, very stable. Very effective balancer for right portion of LG II from the right end through dpy-10, and the right portion of LG III from the right end to between daf-2 and unc-93. mT1(II) is probably LGII (right) translocated to LG III (left), disjoins from normal LG III. mT1(III) is probably LG III (right) translocated to LG II (left), disjoins from normal LG II.
Origin/Mutagen: Gamma irradiation of dpy-10(e128)/unc-85(e1414) rol-1(e91) II.
|
Edgley, M.L., and Riddle, D.L., 2001. |
mnC1(II) | Summary: Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for right portion of LG II from around dpy-10 to around unc-52.
Origin/Mutagen: X-ray mutagenesis of unc-4/dpy-10 unc-52.
|
Herman, R.K., 1978; Sigurdson, D.C., Spanier, G.J., and Herman, R.K., 1984. |
mnDp1(X;V) | Summary: Translocated duplication, well characterized, does not recombine with normal homologues. Very effective balancer for right portion of LG X from right end through let-4.
Origin/Mutagen: ~7500-R X-ray mutagenesis of N2 males.
|
Herman, R.K., Albertson, D.G., and Brenner, S., 1976; Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Meneely P.M., and Herman, R.K., 1981. |
mnDp3(X;f) | Summary: Free duplication, well characterized, does not recombine with normal LG X. Effective balancer for right portion of LG X from around the right end through unc-9.
Origin/Mutagen: ~7500-R X-ray mutagenesis of N2 males.
|
Herman, R.K., Albertson, D.G., and Brenner, S., 1976; Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Herman, R.K., 1984. |
mnDp10(X;I) | Summary: Translocated duplication, well characterized, does not recombine with normal LG X. Effective balancer for right portion of LG X from around the right end through lin-2.
Origin/Mutagen: ~7500-R X-ray mutagenesis of N2 males.
|
Herman, R.K., Madl, J.E., and Kari, C.K., 1979; Meneely P.M., and Herman, R.K., 1981. |
mnDp33(X;IV) | Summary: Translocated duplication, well characterized, does not recombine with normal X. Effective balancer for small region of left portion of LG X, from lin-18 to osm-5 (inclusive).
Origin/Mutagen: ~7500 R X-ray mutagenesis of N2 males.
|
Herman, R.K., Madl, J.E., and Kari, C.K., 1979. |
mnDp34(II) | Summary: mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53.
Origin/Mutagen ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120).
|
Herman, R.K., Madl, J.E., and Kari, C.K., 1979. |
mnDp35(II) | Summary: mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53.
Origin: ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120).
|
Herman, R.K., Madl, J.E., and Kari, C.K., 1979. |
mnDp36(II) | Summary: mnDp34-36 are independently isolated free duplications with apparently identical genetic extents. Well characterized, do not recombine with normal homologues. Very effective balancers for right portion of LG II from around unc-52 through unc-53.
Origin/Mutagen: ~7500-R X-ray mutagenesis of mnC1[dpy-10(e128) unc-52(e444)]/ unc-4(e120).
|
Herman, R.K., Madl, J.E., and Kari, C.K., 1979. |
nT1(IV;V) | Summary: Translocation, moderately well characterized, very stable. Very effective balancer for right portion of LG IV from right end through unc-17, and for left portion of LG V from left end through unc-76.
Origin/Mutagen: Spontaneous.
|
Ferguson, E.L., and Horvitz, H.R., 1985; Clark, D.V., Rogalski, T.M., Donati, L.M., and Baillie, D.L., 1988; Rogalski, T.M., and Riddle, D.L., 1988; J. Kimble, pers. comm. |
qC1(III) | Summary: Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for the left portion of LG III from tra-1 to at least dpy-1.
Origin/Mutagen: 7200-R gamma-irradiation mutagenesis of unc-32(e189)/dpy-19(e1259).
|
Austin, J., and Kimble, J., 1989; J. Austin, E. Goodwin, and J. Kimble, pers. comm.; Ha and Baillie, unpublished results. |
sC1(III) | Summary: Dominant crossover suppressor, uncharacterized with regard to structure, very stable. Very effective balancer for an approximately 15-mu portion of LG III from around unc-45 to near daf-2.
Origin/Mutagen: 2000-R gamma-irradiation mutagenesis of N2 males.
|
Stewart and Baillie, unpublished results. |
sC4(V) | Summary: Dominant crossover suppressor, uncharacterized with regard to structure, moderately stable. Balances right portion of LG V from rol-9 to unc-76.
Origin/Mutagen: 2000-R gamma-irradiation mutagenesis of dpy-21/unc-76 rol-9.
|
Stewart and Baillie, unpublished results. |
sDp2(I;f) | Summary: Free duplication, well characterized, does not recombine with normal homologues. Very effective balancer for the left portion of LG I from the left end through unc-15 (just left of unc-13).
Origin/Mutagen: 7500-R gamma-irradiation mutagenesis of N2 males.
|
Rose, A.M., Baillie, D.L., and Curran, J., 1984; Howell, A.M., Gilmour, S.G., Mancebo, R.A., and Rose, A.M., 1987; Howell, A.M., and Rose, A.M., 1990; McKim, K.S., and Rose, A.M., 1990; McKim, K.S., Starr, T., and Rose, A.M., 1992; McKim, K.S., Peters, K., and Rose, A.M., 1993. |
sDp3(III;f) | Summary: Free duplication, well characterized, does not recombine with normal homologues. Very effective balancer for left portion of LG III from around unc-86 through at least dpy-1 (does not extend to unc-45).
Origin/Mutagen: 1500-R gamma-irradiation mutagenesis of dpy-18/eT1 III; unc-46/ eT1 V.
|
Rosenbluth, R.E., Cuddeford, C., and Baillie, D.L., 1985. |
stDp2(X;II) | Summary: Translocated duplication, moderately well characterized, not observed to recombine with normal LG X. Very effective balancer for small region in the center of LG X, from around unc-58 to around unc-6.
Recommended use: General balancing, strain construction, strain maintenance.
|
Meneely, P.M. and Wood, W.B., 1984. |
szDp1(I;X;f) | Summary: Complex free duplication, well characterized, does not recombine with normal LG I. Very effective balancer for the left portion of LG I from the left end through unc-13. Consists of one half-translocation [szT1(X)] from szT1 maintained in addition to a normal chromosome complement.
Origin/Mutagen: Exceptional Unc-3 segregant from dpy-5/szT1[lon-2] I; unc-3/szT1 X.
|
McKim, K.S., Howell, A.M., and Rose, A.M., 1988; McKim, K.S., Starr, T., and Rose, A.M., 1992; McKim, K.S., Peters, K., and Rose, A.M., 1993; McKim, K.S., and Rose, A.M., 1990. |
szT1(I;X) | Summary: Reciprocal translocation, well characterized, very stable. Effective balancer for left portion of LG I through unc-13, nearly all of LG X from right end to around dpy-3. szT1(I) is large segment of LG X (right) translocated to LG I, disjoins from normal LG I. szT1(X) is LG I (left) translocated to fragment of LG X (left), disjoins from normal LG X.
Origin/Mutagen: 7000-R gamma-ray mutagenesis of lon-2(e678)/dpy-8(e1321) unc-3(e151)hermaphrodites.
|
Fodor, A., and Deak, P., 1985; McKim, K.S., Howell, A.M., and Rose, A.M., 1988; Howell, A.M., and Rose, A.M., 1990; McKim, K.S., and Rose, A.M., 1990. |
yDp1(IV;V;f) | Summary: Complex free duplication, moderately well characterized, not observed to recombine with either normal homologue. Very effective balancer for right portion of LG IV from around dpy-4 to around unc-22, and left portion of LG V from around unc-34 through yDp1.
Origin/Mutagen: EMS mutagenesis of unc-22(s7) dpy-26(n199)IV/nT1[unc(n754) let](IV;V).
|
DeLong, L., Casson, L.P., and Meyer, B.J., 1987; Plenefisch, J.D., DeLong, L., and Meyer, B.J., 1989; Yuan, J.Y., and Horvitz, H.R., 1990. |