WormBase-Caltech Weekly Calls

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2011 Meetings

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July 7, 2011

Root Passwords for all machines

  • Send to Paul for emergency access


Issue Trackers

  • All code in production use in BitBucket or equivalent
  • Textpresso - Subversion (code can be shared)
  • WormBase - Bitbucket, GitHub (can commit code)
  • Todd says Github for code is best


Alex Bishop Help Desk E-mail

  • Interolog Finder
  • FlyBase will include links soon
  • Is WormBase interested connecting to it?
  • Can it be sustainably maintained?
  • We should make a link under the Tools section of WormBase
  • Interolog Finder provides cytoscape files
  • Does Cytoscape have a web interface?


Elbrus is currently working stably

  • Raymond stabilized Elbrus
  • Elbrus is a frankenstein now
  • Sanger/EBI taking over the RNAi mappings
  • Will discuss with Igor once we determine the remaining issues
  • Elbrus still needed for RNAi scripts to generate ACE files


Oliver Hobert correcting expression patterns occasionally

  • Ask Oliver to point out what is missing
  • Also ask Shawn Lockery
  • Cell-specific markers
  • Curated as transgenes
  • Can link to specific promoters if transgenes present
  • Bottom of every transgene page has a link to the static Marker table
  • Check on new Beta version of WormBase website


Changing language of e-mail to authors to confirm data

  • Non-nematode papers in WormBase via Cecilia?
  • Authors sending all papers in their CV


Expression Cluster data curation

  • Including GO terms, life stage, etc.
  • Link to process pages?


Expression Cartoons

  • Attempting to depict expression patterns by separate images for each tissue
  • Would be nice to have a consolidated image with the option to expand to see individual tissue images
  • Will maintain consolidated and expandable images for each gene as well as each expression pattern for each gene
  • Trying to capture "Certain", "Uncertain", and "Partial" curation tags


Molecule curation

  • Will need a molecule page on WormBase at some point
  • Need a way to handle molecules that do not have a Mesh IDs
  • Will replace WBMolecule IDs with Mesh IDs when they become available
  • WBMolecule ID will be made a synonym of the molecule name alongside the Mesh ID
  • Need to consider how the data will be stored and referred to in the long term (via ACE files etc.)


July 14, 2011

Concise descriptions

  • OA being developed for concise descriptions
  • Wiki page for concise descriptions
  • User Community involvement - individual user curation/annotation


Diseases

  • Managing disease relevance tags in appropriate models
  • Relating human disease genes to C. elegans orthologous genes
  • Developing an integrated view for users to browse human disease relevance
  • Manual vs Automated curation processes


Worm Breeder's Gazette mass e-mails

  • Users complained about e-mails going to old e-mail addresses
  • Will only e-mail the most current e-mail on a user's profile


GitHub

  • WormBase curation repository
  • Should Juancarlos put postgres (and other) cgi's there?
  • Make a separate Tazendra repository?
  • Generate symbolic links for flat files (non-code)?
  • Are we limited in the number of repositories we can have? Cost-dependent
  • We could pay more for more repositories; is it worth it?
  • Make another account separate from Todd's? Probably not; should keep consolidated in one account
  • Do different dependencies cause problems?
  • We will ask Todd about what he thinks is best
  • OA code could eventually go to GitHub as well Code already in github -- J
  • Textpresso code can go to GitHub as well


Ontology Browser

  • Aldrin installing Amigo
  • How long should installing Amigo take?
  • Get some input from GO Consortium


Genetic Interactions from Textpresso

  • Where are relevant paper sentences stored?
  • Should we pull out sentences used by Andrei for interactions curation?
  • Alternatively, redo a Textpresso search for relevant gene names, etc.
  • Can we adequately find allele information?


Interolog Finder

  • How to incorporate Interolog Finder into relevant gene pages?
  • Maybe make a database object for each C. elegans Interolog Finder interaction
  • Can we display our own data in Cytoscape? Interolog Finder data?
  • Are Wei-wei's data being updated?


Rearrangements

  • Want to change the variation auto-complete file
  • Dead allele objects
  • Problem: some Rearrangment objects are considered alleles/variations, others are dead or are not considered alleles
  • How do we define/distinguish between Rearrangements/Deficiencies and Alleles?
  • All are variations
  • Do we make alleles and rearrangements mutually exclusive?
  • Since all are variations, we handle each generically as a WBVar### object
  • The distinction would just need to be made at the point of object creation


Anatomy Ontology

  • Obsolete terms dumped from the Anatomy Ontology
  • Will flag obsolete terms or try to remove from dump