Difference between revisions of "WormBase-Caltech Weekly Calls"

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=== Pharyngeal phenotype terms ===
 
=== Pharyngeal phenotype terms ===
* Karen needs pharyngeal pumping phenotype terms for NemaMetrix micropublications
+
* Karen has made pharyngeal pumping phenotype terms for NemaMetrix micropublications
* NemaMetrix experiments often involve serotonin-induced pharyngeal pumping  
+
* It is common for many groups to involve serotonin-induced pharyngeal pumping to analyze strains; we do have a serotonin-induced pharyngeal pumping variant term- should I use this for all pumping phenotypes? In addition we have an EPG variant term and again, people tend to use EPGs to record pumping activity - should all reported pharyngeal pumping phenotypes that were measured  by EPGs be annotated with this term?  These questions highlight a need to revisit the pharyngeal phenotype branch and clarify how we should be focused on annotating these reported annotations.
* Karen asking Raymond to help with pharyngeal phenotype term organization
+
* Karen asked Raymond/Gary and any other person interested in the group to help with pharyngeal phenotype term organization
 
* Raymond: Not very familiar with the existing usage of the terms and phenotype ontology structure wrt pharyngeal terms
 
* Raymond: Not very familiar with the existing usage of the terms and phenotype ontology structure wrt pharyngeal terms
* Authors will submit phenotype data as part of the micropublication process
+
* Authors submit phenotype data as part of the micropublication process
 
* Proposal for phenotype ontology going forward: create terms with logical definitions (OWL statements)
 
* Proposal for phenotype ontology going forward: create terms with logical definitions (OWL statements)
 
* We will start exploring more usage of logical definitions for phenotypes
 
* We will start exploring more usage of logical definitions for phenotypes
 
* Will start meeting Thursday afternoons, starting next week (Feb 9), 1:30pm Pacific
 
* Will start meeting Thursday afternoons, starting next week (Feb 9), 1:30pm Pacific
 +
* Karen will prepare the terms to be looked through.....
  
 
=== SObA graph for GO ===
 
=== SObA graph for GO ===

Revision as of 01:07, 3 February 2017

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2017 Meetings

January


February 2, 2017

Methods in Molecular Biology chapter

  • Chris and Mary Ann will be in touch with individuals about section writing
  • Karen: FlyBase chapter has small sections rather than long articles about their pages; should we keep our sections small; a few paragraphs each?
    • As long as we stick to the "how to" focus, we can write as much as needed
  • Raymond: We should try to write so that the content remains pertinent for a while

Pharyngeal phenotype terms

  • Karen has made pharyngeal pumping phenotype terms for NemaMetrix micropublications
  • It is common for many groups to involve serotonin-induced pharyngeal pumping to analyze strains; we do have a serotonin-induced pharyngeal pumping variant term- should I use this for all pumping phenotypes? In addition we have an EPG variant term and again, people tend to use EPGs to record pumping activity - should all reported pharyngeal pumping phenotypes that were measured by EPGs be annotated with this term? These questions highlight a need to revisit the pharyngeal phenotype branch and clarify how we should be focused on annotating these reported annotations.
  • Karen asked Raymond/Gary and any other person interested in the group to help with pharyngeal phenotype term organization
  • Raymond: Not very familiar with the existing usage of the terms and phenotype ontology structure wrt pharyngeal terms
  • Authors submit phenotype data as part of the micropublication process
  • Proposal for phenotype ontology going forward: create terms with logical definitions (OWL statements)
  • We will start exploring more usage of logical definitions for phenotypes
  • Will start meeting Thursday afternoons, starting next week (Feb 9), 1:30pm Pacific
  • Karen will prepare the terms to be looked through.....

SObA graph for GO

  • Juancarlos & Raymond making progress
  • Added toggling for different roots of GO
  • Difficult to navigate graph when lots of terms (e.g. tax-4)
  • What can be done to improve the display?
  • Filtering out IEA annotations; currently only for phenotype annotations; will expand to all IEA annotations
  • Kimberly generating GO slim, 15-20 terms for each branch of GO, possible to use in ribbon display
  • Could we distinguish between is_a, part_of, and regulates relationships?
  • To simplify graph, could we further minimize the display of higher level/indirect nodes?
  • Would we want parallel paths to root to be trimmed?