Difference between revisions of "WormBase-Caltech Weekly Calls"

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== February 11, 2016 ==
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[[WormBase-Caltech_Weekly_Calls_February_2016|February]]
  
=== Postgres data not in ACEDB ===
 
* Should we this data get into ACEDB to be converted to Datomic (via the existing pipeline)? Maybe, but only temporarily
 
* We will need to learn to model in Datomic to start building curation tools that run off of Datomic
 
* Juancarlos has access to Colonnade & trAceView (table maker tool and web interface to view Datomic data like in ACEDB)
 
* For long term, we will want to build a curation tool directly on top of Datomic; will need to model currently un-dumped fields in Datomic
 
* Juancarlos has a few action items to test reading from and writing to Datomic in a simple manner
 
* Paper editor may be best form to start Datomic transition, since it doesn't deal with N1-objects changing with N2-other-objects
 
* Bulk updates of data not edited through the OA may be another good starting point, as those pipelines will need to change Datomic directly
 
  
=== CITace upload ===
 
* Upload files to Wen by Tuesday Feb 16, 10am
 
  
=== Life stage ontology update ===
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== March 3, 2016 ==
* To accommodate flat worms, will make "worm life stage" root node with "platyhelminth (flatworm)..." and "nematode (roundworm)..." children
 
  
=== Timestamps ===
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=== Topic 1 ===
* Data in OA's has timestamp history, but all data first imported in bulk has one 'epoch' timestamp
 
* Chris looking into older timestamps from older versions of WS/ACEDB
 
* Will be good to clarify how older timestamps will be stored in Datomic going forward (i.e. a timestamp field separate from a Datomic intrinsic timestamp?)
 
* Would be best to have as many original timestamps as possible
 
  
  
== February 18, 2016 ==
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=== Topic 2 ===
 
 
=== Automated descriptions ===
 
* Plan is to phase-out the manually written descriptions
 
* ubc-9 gene had old (2004) manually written description but no automated description (Wen)
 
* Eventually we would want all descriptions to be automated; we can't maintain manual descriptions for all genes
 
* Kimberly and Ranjana will review older descriptions to see what else can be automated
 
 
 
=== Upload summary ===
 
* Wen updated language for each line of the Citace upload summary to be more human readable
 
 
 
=== SObA legend ===
 
* Updated SObA legend to include an indicator of what the arrows indicate
 
 
 
=== Transgenome data ===
 
* Daniela asking for the data from labs (Mihail Sarov)
 
 
 
=== WS254 upload ===
 
* When is the next data upload? End of March? End of April?
 
 
 
 
 
== February 25, 2016 ==
 
 
 
=== Transgenome project ===
 
* Sibyl and Daniela spoke with lab
 
* Will setup an API for continuous updates of data
 
* ~14,000 constructs (~14,000 genes), ~300 analyzed so far, ~3,000 pictures so far
 
* WormBase will receive regular updates of Expr_pattern objects as .ACE
 
** Expr_pattern objects from the project will not be touched locally by WB curators; only using their forms
 
* We will get a one-time dump of all transgenes and constructs that we can edit locally
 
 
 
=== Expression cluster anatomy data ===
 
* Would like to add anatomy expression data from expression clusters to GAF
 
* Using enrichment status for new lines in GAF
 
* May need more evidence codes to accommodate; Inferred from Expression Pattern (IEP) usage vs. Inferred from Direct Assay (IDA). Kimberly advised IDA is appropriate for gene expression data.
 
 
 
=== Timestamps ===
 
* Trying to restore time stamps for older annotations that are not accurately captured in Postgres timestamps
 
* Wen rebuilding old releases; we only want to restore time stamps for object creation, not detailed attributes
 
 
 
=== Objectifying phenotype annotations ===
 
* Chris thinking about objectifying allele-phenotype and transgene-phenotype annotations
 
* Would make it easier to query out annotation-specific data
 
* Chris and Juancarlos will work to consider future querying difficulties in Datomic
 
 
 
=== Caprica revived ===
 
* Running Ubuntu 14
 
* Has 20GB memory, could have up to 24GB
 
* Could be used for other projects, like testing Datomic
 

Revision as of 16:48, 3 March 2016