Difference between revisions of "User Guide/TEA"

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== '''Tissue Enrichment Analysis''' ==
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== '''Gene Set Enrichment Analysis''' ==
  
 
== Submit ==
 
== Submit ==
  
 
Enter a gene list consisting of any accepted C. elegans gene names separated by spaces, colons or tabs into the box. Alternatively, input a plain-text file of gene names separated by spaces, colons or tabs using the 'Choose file' button. Text files must be plain text (.txt).
 
Enter a gene list consisting of any accepted C. elegans gene names separated by spaces, colons or tabs into the box. Alternatively, input a plain-text file of gene names separated by spaces, colons or tabs using the 'Choose file' button. Text files must be plain text (.txt).
The program returns enriched tissues as assessed by a hypergeometric function, after FDR correction. A bar chart containing the top 15 (or less) enriched terms, sorted by increasing q-value and by decreasing fold-change is automatically generated. Bar coloring is intended to improve readability, and color does not convey information.
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The program returns enriched terms as assessed by a hypergeometric function, after FDR correction. A bar chart containing the top 15 (or less) enriched terms, sorted by increasing q-value and by decreasing fold-change is automatically generated. Bar coloring is intended to improve readability, and color does not convey information.
Sometimes the program's running time is longer than the set 'timeout' interval and it would cause a "504 Gateway Timeout" error. If that happens, please refresh the web page.
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<p>Optionally, provide a background gene set as a csv (or simple text) file with a single column without a column name. Gene names must be in wbid format.
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*<b>Sometimes the program's running time is longer than the set 'timeout' interval and it would cause a "504 Gateway Timeout" error. If that happens, please refresh the web page.</b>
  
 
== Result ==
 
== Result ==
The bar chart automatically displays up to 15 enriched tissues sorted by q-value (lowest q-value on top) and secondarily by fold-change (higher fold change on top) in case of tied q-values. Colors are meant to improve readability and do not convey information.
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The Result table shows all significantly enriched terms, those that have a Q value < 0.1, sorted by their P values.
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The bar chart displays up to 15 significantly enriched terms. Colors are meant to improve readability and do not convey information.
  
 
== Citation ==
 
== Citation ==
  
 
[http://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-016-1229-9 David Angeles-Albores, Raymond Y. N. Lee, Juancarlos Chan and Paul W. Sternberg, 2016. "Tissue enrichment analysis for C. elegans genomics", BMC Bioinformatics 17:366]
 
[http://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-016-1229-9 David Angeles-Albores, Raymond Y. N. Lee, Juancarlos Chan and Paul W. Sternberg, 2016. "Tissue enrichment analysis for C. elegans genomics", BMC Bioinformatics 17:366]
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[https://doi.org/10.17912/W25Q2N Angeles-Albores, D; Lee, RYN; Chan, J; Sternberg, PW (2018): Two new functions in the WormBase Enrichment Suite. Micropublication: biology. Dataset. https://doi.org/10.17912/W25Q2N]

Latest revision as of 22:27, 5 August 2019

Gene Set Enrichment Analysis

Submit

Enter a gene list consisting of any accepted C. elegans gene names separated by spaces, colons or tabs into the box. Alternatively, input a plain-text file of gene names separated by spaces, colons or tabs using the 'Choose file' button. Text files must be plain text (.txt). The program returns enriched terms as assessed by a hypergeometric function, after FDR correction. A bar chart containing the top 15 (or less) enriched terms, sorted by increasing q-value and by decreasing fold-change is automatically generated. Bar coloring is intended to improve readability, and color does not convey information.

Optionally, provide a background gene set as a csv (or simple text) file with a single column without a column name. Gene names must be in wbid format.

  • Sometimes the program's running time is longer than the set 'timeout' interval and it would cause a "504 Gateway Timeout" error. If that happens, please refresh the web page.

Result

The Result table shows all significantly enriched terms, those that have a Q value < 0.1, sorted by their P values.

The bar chart displays up to 15 significantly enriched terms. Colors are meant to improve readability and do not convey information.

Citation

David Angeles-Albores, Raymond Y. N. Lee, Juancarlos Chan and Paul W. Sternberg, 2016. "Tissue enrichment analysis for C. elegans genomics", BMC Bioinformatics 17:366

Angeles-Albores, D; Lee, RYN; Chan, J; Sternberg, PW (2018): Two new functions in the WormBase Enrichment Suite. Micropublication: biology. Dataset. https://doi.org/10.17912/W25Q2N