Difference between revisions of "UserGuide:SimpleMine"

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== SimpleMine Users' Guide ==
 
== SimpleMine Users' Guide ==
  
SimpleMine is designed for biologists who want to get essential information for a list of genes without any command-line or programming skill. We consider the following as "essential information" based on user feedback. Please feel free to contact us if you want to include more information in the list.   
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SimpleMine is designed for biologists who want to get essential information for a list of genes without any command-line or programming skill. We consider the following as "essential information" based on user feedback. Please feel free to contact us if you want to include more information on the list.   
  
 
'''Names, Identifiers, Sequences, Species'''
 
'''Names, Identifiers, Sequences, Species'''
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Genetic Map Position
 
Genetic Map Position
  
RNAi Phenotype Observed
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RNAi Phenotype Observed: Display the phenotype ontology names sorted in alphabetic order.
  
Allele Phenotype Observed
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Allele Phenotype Observed: Display the phenotype ontology names sorted in alphabetic order.
  
Coding_exon Non_silent Allele: Among those alleles that were sequenced, we exclude polymorphisms and alleles that fall in an intron, 5' UTR or 3' UTR.
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Coding_exon Non_silent Allele: Among those alleles that were sequenced, we exclude polymorphisms and alleles that fall in any coding exon. Alleles are sorted and displayed according to the following order of their types: Deletion, Insertion, Substitution, Tandem_duplication. Each allele entry contains three bar-separated fields: allele name, allele type, and molecular change.  
  
 
Interacting Gene: We only display experimentally confirmed gene interactions.  
 
Interacting Gene: We only display experimentally confirmed gene interactions.  
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Expr_pattern Tissue: Anatomical expression based on GFP, immunoprecipitation, In_situ, etc.
 
Expr_pattern Tissue: Anatomical expression based on GFP, immunoprecipitation, In_situ, etc.
  
Genomic Study Tissue: Tissue enrichment based on microarray, RNA-Seq, and proteomics studies.  
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Genomic Study Tissue: Tissue enrichment based on the microarray, RNA-Seq, and proteomics studies.  
  
 
Expr_pattern LifeStage: Developmental expression based on GFP, immunoprecipitation, In_situ, etc.
 
Expr_pattern LifeStage: Developmental expression based on GFP, immunoprecipitation, In_situ, etc.
  
Genomic Study LifeStage: Developmental expression based on microarray, RNA-Seq, and proteomics studies.  
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Genomic Study LifeStage: Developmental expression based on the microarray, RNA-Seq, and proteomics studies.  
  
  
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'''Functional Annotation and References'''
 
'''Functional Annotation and References'''
  
Gene Ontology Association: Gene Ontology terms that were annotated to the gene.
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Gene Ontology Association: Display the names of gene ontology terms that were annotated to the gene sorted in alphabetic order
  
 
Concise Description: Outdated manually written descriptions of the gene functions.
 
Concise Description: Outdated manually written descriptions of the gene functions.
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Automated Description: Up-to-date gene description machine generated based on the current WormBase data.
 
Automated Description: Up-to-date gene description machine generated based on the current WormBase data.
  
Expression Cluster Summary: Gene regulation, molecular regulation, and tissue enrichment summary based on microarray, RNA-Seq, and proteomics studies.  
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Expression Cluster Summary: Gene regulation, molecular regulation, and tissue enrichment summary based on the microarray, RNA-Seq, and proteomics studies.  
  
 
Reference: Primary research articles that studied the gene.
 
Reference: Primary research articles that studied the gene.

Revision as of 07:00, 12 August 2020

SimpleMine Users' Guide

SimpleMine is designed for biologists who want to get essential information for a list of genes without any command-line or programming skill. We consider the following as "essential information" based on user feedback. Please feel free to contact us if you want to include more information on the list.

Names, Identifiers, Sequences, Species

WormBase Gene ID

Public Name

Species

Sequence Name

Other Name

Transcript

Operon

WormPep

Protein Domain

UniProt

Reference UniProt ID

TreeFam

RefSeq_mRNA

RefSeq_protein


Genetics, Phenotypes, Interactions

Genetic Map Position

RNAi Phenotype Observed: Display the phenotype ontology names sorted in alphabetic order.

Allele Phenotype Observed: Display the phenotype ontology names sorted in alphabetic order.

Coding_exon Non_silent Allele: Among those alleles that were sequenced, we exclude polymorphisms and alleles that fall in any coding exon. Alleles are sorted and displayed according to the following order of their types: Deletion, Insertion, Substitution, Tandem_duplication. Each allele entry contains three bar-separated fields: allele name, allele type, and molecular change.

Interacting Gene: We only display experimentally confirmed gene interactions.


Expression

Expr_pattern Tissue: Anatomical expression based on GFP, immunoprecipitation, In_situ, etc.

Genomic Study Tissue: Tissue enrichment based on the microarray, RNA-Seq, and proteomics studies.

Expr_pattern LifeStage: Developmental expression based on GFP, immunoprecipitation, In_situ, etc.

Genomic Study LifeStage: Developmental expression based on the microarray, RNA-Seq, and proteomics studies.


Human Orthologs and Disease

Disease Info

Human Ortholog


Functional Annotation and References

Gene Ontology Association: Display the names of gene ontology terms that were annotated to the gene sorted in alphabetic order

Concise Description: Outdated manually written descriptions of the gene functions.

Automated Description: Up-to-date gene description machine generated based on the current WormBase data.

Expression Cluster Summary: Gene regulation, molecular regulation, and tissue enrichment summary based on the microarray, RNA-Seq, and proteomics studies.

Reference: Primary research articles that studied the gene.