Difference between revisions of "Topic pages"

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* Home for pathway views of data from Reactome, BioCyc, and Nemapath
 
* Home for pathway views of data from Reactome, BioCyc, and Nemapath
  
=Summary of page elements=
+
=WBProcess OA=
 +
 
 +
TAB1
 +
'''WBProcessID''' auto-incremental based on new record dump as WBProcess : "WBbiopr:00000x"
 +
'''Process_term'''  text
 +
'''Summary''' big text
 +
'''Other_name''' big text, values will be pipe separated
 +
'''Related_process''' XREF to WBProcess -multi-ontology field, autocomplete on Process_term
 +
'''Taxon''' multi-ontology of NCBITaxonomy ID, autocomplete on
 +
'''WBProcess''' ontology autocomplete on process_term
 +
'''Remark''' big text
 +
 +
TAB2
 +
'''WBPaper''' ontology autocomplete on WBPaperID
 +
'''Gene''' multi-ontology autocomplete on public_name
 +
'''Expression_cluster'''  multi-ontology (will need to query for this an add to OA ontology file with rest  of it)
 +
'''Interaction''' multi-ontology, autocomplete on gene, term info must have WBPaperID, all interactors,  and  interaction type.
 +
'''Anatomy_term''' multi-ontology autocomplete on name
 +
'''Life_stage''' multi-ontology autocomplete on name
 +
'''Molecule''' multi-ontology  autocomplete on name and synonym
 +
'''Phenotype''' multi-ontology  autocomplete on name and synonym
 +
'''GO_term''' multi-ontology autocomplete on name and synonym
 +
 +
TAB3
 +
'''Picture''' multi-ontology autocomplete on ID
 +
'''Movie''' multi-ontology  autocomplete on ID
 +
'''Pathway Database''' ontology  autocomplete on name
 +
'''Pathway accession''' text
 +
 
 +
'''
 +
 
 +
 
 +
 
 +
 
 +
 
 +
===Cells / Anatomy===
 +
* Mined from gene function?
 +
* Assigned manually from paper/reviews
 +
* Display should be embedded anatomy ontology window pointing to relevant cells/tissue objects.
 +
* Eventually, this should be the whole worm image or cell image (Neurobrowse where appropriate?)
 +
 
 +
====Cell component====
 +
* GO:CC associated with process with references.
 +
* Mined through gene GO assignments
 +
 
 +
===GO biological processes===
 +
* Embedded gene ontology window pointing to relevant GO biological process and genes.
 +
* Each process term will be manually mapped to a GO term, following the hierarchy of the GO ontology when useful
 +
 
 +
===Phenotypes===
 +
* Phenotypes from RNAi experiments, variations in major genes, discussed in reviews, with references.
 +
* Process terms will be associated with a phenotype through the GO2Phenotype mapping (curator validation will be needed)
 +
* For those phenotypes that are not associated through the GO2Phenotype mapping, a curator will do this manually, with feedback to GO and Phenotype curators for coordination of efforts.
 +
 
 +
===Chemicals/small molecules===
 +
* Drug/chemical/small molecule, CHEBI_ID, with references.
 +
 
 +
===Genetic interactions===
 +
* Manually associated
 +
* With the process with references.
 +
* Gene interaction networks (N-browse view?)
 +
 
 +
===Microarray experiments===
 +
* Expression clusters only (all microarray experiments should have these cluster views of the results)
 +
* link to SPELL page for microarray data
 +
 
 +
===Related human disease===
 +
* OMIM assignments based on process-associated genes, ranked by most evidence supported.
 +
 
 +
===Pathway/Reaction===
 +
* Metabolic pathways: BioCyc, Reactome, NemaPath (KEGG)
 +
* Other pathways: Reactome
 +
 
 +
===Resources===
 +
* WormBook  (Viewed as WormBook chapter title and author (WBPerson/Author page))
 +
* WormAtlas  (WormAtlas page(s) link, display page title)
 +
 
 +
==Process OA==
 +
 
 
===Summary===
 
===Summary===
 
A general summary of the process term.  Can be extracted from WormBook if possible.
 
A general summary of the process term.  Can be extracted from WormBook if possible.

Revision as of 23:17, 30 August 2011

back to' Caltech documentation
Other process related pages

Goals of the process pages

  • Portal for larger biomedical community into C. elegans gene function.
  • Context for data that fits within a larger biological picture such as microarray results, and responses to chemical/drugs, i.e. orphaned data
  • On the fly update addendum to WormBook chapters
    • process pages will dissect the chapters and link them to entities in WormBase,
    • process pages will link summaries of processed with the most recent acedb data
  • Home for pathway views of data from Reactome, BioCyc, and Nemapath

WBProcess OA

TAB1
WBProcessID auto-incremental based on new record dump as WBProcess : "WBbiopr:00000x"
Process_term  text
Summary big text
Other_name big text, values will be pipe separated
Related_process XREF to WBProcess -multi-ontology field, autocomplete on Process_term
Taxon multi-ontology of NCBITaxonomy ID, autocomplete on
WBProcess ontology autocomplete on process_term
Remark big text 

TAB2
WBPaper ontology autocomplete on WBPaperID
Gene multi-ontology autocomplete on public_name
Expression_cluster  multi-ontology (will need to query for this an add to OA ontology file with rest  of it)
Interaction multi-ontology, autocomplete on gene, term info must have WBPaperID, all interactors,  and  interaction type.
Anatomy_term multi-ontology autocomplete on name
Life_stage multi-ontology autocomplete on name
Molecule multi-ontology  autocomplete on name and synonym
Phenotype multi-ontology  autocomplete on name and synonym
GO_term multi-ontology autocomplete on name and synonym

TAB3
Picture multi-ontology autocomplete on ID
Movie multi-ontology  autocomplete on ID
Pathway Database ontology  autocomplete on name
Pathway accession text



Cells / Anatomy

  • Mined from gene function?
  • Assigned manually from paper/reviews
  • Display should be embedded anatomy ontology window pointing to relevant cells/tissue objects.
  • Eventually, this should be the whole worm image or cell image (Neurobrowse where appropriate?)

Cell component

  • GO:CC associated with process with references.
  • Mined through gene GO assignments

GO biological processes

  • Embedded gene ontology window pointing to relevant GO biological process and genes.
  • Each process term will be manually mapped to a GO term, following the hierarchy of the GO ontology when useful

Phenotypes

  • Phenotypes from RNAi experiments, variations in major genes, discussed in reviews, with references.
  • Process terms will be associated with a phenotype through the GO2Phenotype mapping (curator validation will be needed)
  • For those phenotypes that are not associated through the GO2Phenotype mapping, a curator will do this manually, with feedback to GO and Phenotype curators for coordination of efforts.

Chemicals/small molecules

  • Drug/chemical/small molecule, CHEBI_ID, with references.

Genetic interactions

  • Manually associated
  • With the process with references.
  • Gene interaction networks (N-browse view?)

Microarray experiments

  • Expression clusters only (all microarray experiments should have these cluster views of the results)
  • link to SPELL page for microarray data

Related human disease

  • OMIM assignments based on process-associated genes, ranked by most evidence supported.

Pathway/Reaction

  • Metabolic pathways: BioCyc, Reactome, NemaPath (KEGG)
  • Other pathways: Reactome

Resources

  • WormBook (Viewed as WormBook chapter title and author (WBPerson/Author page))
  • WormAtlas (WormAtlas page(s) link, display page title)

Process OA

Summary

A general summary of the process term. Can be extracted from WormBook if possible.

Genes

Genes related to the process with references.

  • Mined from GO
  • Mined from Phenotype
  • Assigned manually: coordinate with GO and Phenotype curators?

Cells / Anatomy

  • Mined from gene function?
  • Assigned manually from paper/reviews
  • Display should be embedded anatomy ontology window pointing to relevant cells/tissue objects.
  • Eventually, this should be the whole worm image or cell image (Neurobrowse where appropriate?)

Cell component

  • GO:CC associated with process with references.
  • Mined through gene GO assignments

GO biological processes

  • Embedded gene ontology window pointing to relevant GO biological process and genes.
  • Each process term will be manually mapped to a GO term, following the hierarchy of the GO ontology when useful

Phenotypes

  • Phenotypes from RNAi experiments, variations in major genes, discussed in reviews, with references.
  • Process terms will be associated with a phenotype through the GO2Phenotype mapping (curator validation will be needed)
  • For those phenotypes that are not associated through the GO2Phenotype mapping, a curator will do this manually, with feedback to GO and Phenotype curators for coordination of efforts.

Chemicals/small molecules

  • Drug/chemical/small molecule, CHEBI_ID, with references.

Genetic interactions

  • Manually associated
  • With the process with references.
  • Gene interaction networks (N-browse view?)

Microarray experiments

  • Expression clusters only (all microarray experiments should have these cluster views of the results)
  • link to SPELL page for microarray data

Related human disease

  • OMIM assignments based on process-associated genes, ranked by most evidence supported.

Subprocesses and pathways

  • List of processes based on WormBook and other reviews. Mined through GO hierarchy

Pathway/Reaction

  • Metabolic pathways: BioCyc, Reactome, NemaPath (KEGG)
  • Other pathways: Reactome

Resources

  • WormBook (Viewed as WormBook chapter title and author (WBPerson/Author page))
  • WormAtlas (WormAtlas page(s) link, display page title)