Reference Genome Reports - Annotation Coverage

Reference Genome Reports - Annotation Coverage

Purpose: To report to the GO Consortium the extent of annotation coverage for Reference Genome genes.

Annotation Coverage Criteria: The Reference Genome Project aims to provide comprehensive annotations for groups of conserved proteins.

At WB, we don't yet have a mechanism to marking genes as comprehensively annotated in our curation database, so currently we're using the following criteria for assessing how comprehensive our annotations are:

Genes containing annotations to two or more ontologies (Biological Process, Molecular Fnction, Cellular Component) are considered comprehensively annotated.

This choice reflects that in C. elegans papers there is predominantly phenotypic analysis (Biological Process) and expression data (Cellular Component), with fewer papers reporting molecular function data.