Optimizing site performance
Optimizing performance of WormBase
1. Here is a good guide from S. Beckman: 
2. Turn off KeepAliveOn
3. Enable perl-status
SetHandler perl-script PerlHandler Apache::Status order deny,allow #deny from all #allow from ... </Location>
(This should be disabled when in production)
4. Check the memory footprint of apache children:
ps -o pid,user,rss,vsize,%cpu,%mem,ucomm -C httpd
5. Monitoring / killing runawy processes Apache::SizeLimit - very handy for killing wild processes perl.startup:
$Apache::SizeLimit::MAX_UNSHARED_SIZE = 300000; # 350 MB $Apache::SizeLimit::CHECK_EVERY_N_REQUESTS = 2;
A module that monitors hanging Apache/mod_perl processes. You define the time in seconds after which the process to be counted as hanging. You also control the polling time between check to check.
When the process is considered as 'hanging' it will be killed and the event logged into a log file. The log file is being opened on append, so you can basically defined the same log file that uses Apache.