Molecule

links to relevant pages
Caltech documentation
Example molecule pages
Molecule model build

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Molecule Curation

Molecule curation will capture chemical and drug entities that have been shown to affect the biology of the worm, as well as allow users to link to other databases that deal with these molecule entities in greater detail.

• What we mean by small molecule
  • drug
  • metabolite (primary and secondary)
  • monomers or very small oligomers of nucleic acids, proteins, and polysaccharides
  • "Large collections of small molecules (molecular weight about 600 or less), of similar or diverse nature which are used for high-throughput screening analysis of the gene function, protein interaction, cellular processing, biochemical pathways, or other chemical interactions." (from nlm.nih.gov and wikipedia)

Drug-phenotype curation

Molecules will be curated for their affects on variation, transgene overexpression, and RNAi gene knockout.

Drug-gene interactions

Molecules will also be curated based on their affect of gene activity within the gene regulation class.