Difference between revisions of "Modeling data for Infectious agents"
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The Experimental_model tag refers to ?DO_term (disease), in cases of study of infectious agents using Elegans, it is not so much a 'disease model' as an infection model, as it sounds a bit silly to talk about elegans as a model for dysentery, as compared to saying it is an infection model for the bacteria, Shigella flexneri. | The Experimental_model tag refers to ?DO_term (disease), in cases of study of infectious agents using Elegans, it is not so much a 'disease model' as an infection model, as it sounds a bit silly to talk about elegans as a model for dysentery, as compared to saying it is an infection model for the bacteria, Shigella flexneri. | ||
− | We will attach this information to Gene, analogous to disease information (similar to the Experimental_model and Potential model tags for Gene). Initially I thought of tagging Genes just as 'Infection_model' but I think it's worthwhile to actually delineate this a bit further and tag genes as either needed for | + | We will attach this information to Gene, analogous to disease information (similar to the Experimental_model and Potential model tags for Gene). Initially I thought of tagging Genes just as 'Infection_model' but I think it's worthwhile to actually delineate this a bit further and tag genes as either needed for pathogen infection or resistance to it, thus the 'Required_for_infection' and 'Resistance_to_infection' tags. |
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====Curating information about the infectious agent-Proposal for ?Strain:==== | ====Curating information about the infectious agent-Proposal for ?Strain:==== |
Revision as of 23:39, 10 February 2014
C. elegans serves as an infection model for various bacteria, fungi and nematodes, in order to study:
- host genes involved in infection and resistance
- bacterial virulence factors
- to identify effective drugs
- drug screening in infection
Model Proposal for ?Gene
The Experimental_model tag refers to ?DO_term (disease), in cases of study of infectious agents using Elegans, it is not so much a 'disease model' as an infection model, as it sounds a bit silly to talk about elegans as a model for dysentery, as compared to saying it is an infection model for the bacteria, Shigella flexneri.
We will attach this information to Gene, analogous to disease information (similar to the Experimental_model and Potential model tags for Gene). Initially I thought of tagging Genes just as 'Infection_model' but I think it's worthwhile to actually delineate this a bit further and tag genes as either needed for pathogen infection or resistance to it, thus the 'Required_for_infection' and 'Resistance_to_infection' tags.
Current Gene model: ?Gene Disease_info Experimental_model ?DO_term XREF Gene_by_biology ?Species #Evidence Potential_model ?DO_term XREF Gene_by_orthology ?Species #Evidence Disease_relevance ?Text ?Species #Evidence Add under ?Gene Disease_info: Infection_model Required_for_infection ?Strain XREF Host_infection_gene ?Species #Evidence Resistance_to_infection ?Strain XREF Host_resistance_gene ?Species #Evidence Infection_model_description ?Text ?Species #Evidence
Curating information about the infectious agent-Proposal for ?Strain:
Similar to Kimberly's issue about capturing information about the bacterial species for GO data, I propose we use the ?Strain model to hold infection data information.
Add to Strain model:
?Strain Infection_model_info Host_infection_gene ?Gene XREF Required_for_infection Host_resistance_gene ?Gene XREF Resistance_to_infection Infection_model_description ?Text ?Species #Evidence