Hinxton 2016.01- Meeting minutes

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January 08, 2016

In attendance: KH, PD, GW, BB, JL

Curation

  • Reviewing "known" genes with poor gene models
    • PD and GW reviewing genes with a GCG name but questionable gene model
    • Many/most of these are members of gene families.
    • Work has involved (and continues to involve) structure changes, new isoforms, and re-classification of CDSs as pseusogenes
  • Review of some CDSs models based on lincRNA data from David Greenstein (U. Minnesota)
  • Comprehensive re-annotation of hlb-1 locus (based on feedback from a researcher from Penn state university)

Development

  • New infrastructure for curating RNASeq meta data
    • Ini file under version control, maintained by a combination of scripts and manual curation
    • Will be a input to a script that generates the Track Hub (labelling tracks correctly etc)
  • Continued work on using Trinity to "distill" RNASeq data for use in UTR addition to coding models

ParaSite

  • Release 5 due soon
    • BioMart currently being build
    • Full testing will be done early next week
      • Focus on C. elegans, and two new assemblies (E. multicularis and H. microstoma)
  • Starting to look into Biomart alternatives (elastic search)
  • ParaSite talk at the EG SAB
  • Lots of work on documentation
  • ParaSite expresso - conversations with Caltech about setting this up