Haemonchus contortus

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Ecology

Haemonchus contortus is an animal endoparasite infecting ruminants worldwide also known as red stomach worm, wire worm or Barber's pole worm, is very common parasite and one the most pathogenic nematodes of ruminants. Adult worms are attached to abomasal mucosa and feed on the blood. It belongs to the Strongylida family, that is closely related to the Rhabditoidea (which contains the Caenorhabditae).

The adult female worm can release between 5,000– 10,000 eggs which will be passed out in the feces. Eggs then develop in moist conditions in the feces and continue to develop into the L1(rhabditiform), and L-2 juvenile stages by feeding on bacteria in the manure. The L-1 stage usually occurs within 4–6 days under the optimal conditions of 24–29 °C. The L-2 rhabditform sheds its cuticle and then develops into the L-3 filiariform infective larvae. The L-3 have a protective cuticle, however under dry hot conditions will not survive long. The L-3 then crawl up the blades of wet grass and wait to be ingested by a grazing animal. Sheep, goats and other ruminants become infected when they graze and eat grasses containing the L3 infecting larvae. The infecting larvae pass through the first three stomachs to reach the abomasum. There the L-3 sheds its cuticle and burrows into the internal layer of the abomasum where they develop into L-4, usually within 48 hours, or pre-adult larvae. The L-4 larvae then molts and develops into the L-5 adult form. The male and female adults mate and live in the abomasum, where they feed upon the blood. (from Wikipedia)

Genomics

WormBase Ressources

  • DNA and protein sequences
  • GFF3 annotation
    • homology
    • protein domains
    • ortholog C.elegans genes

External Ressources