Difference between revisions of "Drugs"
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| + | ==C. elegans as a model system to study drugs== | ||
C. elegans is being used to study: | C. elegans is being used to study: | ||
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*metal toxicity and detoxification | *metal toxicity and detoxification | ||
*the effects of a drug/chemical on disease phenotypes | *the effects of a drug/chemical on disease phenotypes | ||
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Types of drugs being studied include: | Types of drugs being studied include: | ||
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*Antifungal agents | *Antifungal agents | ||
*Antimicrobial agents | *Antimicrobial agents | ||
Latest revision as of 17:51, 15 April 2013
C. elegans as a model system to study drugs
C. elegans is being used to study:
- metal toxicity and detoxification
- the effects of a drug/chemical on disease phenotypes
- identify gene targets for a given drug/chemical
- mode of action of a drug/chemical (MOA)
Types of drugs being studied include:
- Antifungal agents
- Antimicrobial agents
- Antiparasitic drugs--Aldicarb, Ivermectin, Levamisole
- Anti-depressants--Fluoxetine, Imipramine
- Anaesthic--Halothane
- Anticancer drugs--Farnesyltransferase inhibitors (FTIs)
- Anticonvulsants--Ethosuximide, Arimethadione
- Alkaloid drugs--Nicotine
- Immunosuppressants--Prednisone
- Nutritional supplements--Resveratrol, Gingko biloba
- Opioid toxins--MPTP/MPP+
- Pychoactive drug--Ethanol
