Disease and Drugs

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C. elegans as a model system to study disease and disease genes

Human disease gene orthologs in elegans

C. elegans as a model for infection

C. elegans as a model to study biofilms

Using C. elegans to study the effects of space flight

C. elegans as a model system to study drugs

C. elegans is being used to:

  • study the effects of a drug/chemical on disease phenotypes
  • identify gene targets for a given drug/chemical
  • mode of action of a drug/chemical (MOA)

Types of drugs being studied include:

  • Antifungal agents
  • Antimicrobial agents

Textpresso-based systems to flag papers for disease gene ortholog/disease/drug

Pipeline for identifying papers with disease or disease gene ortholog