2018

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Annotation Progress

WormBase GO Annotation Statistics as of December 5, 2018

Manual annotation statistics are summarized in Tables 1 - 3.

Total number of unique manual annotations: 52557 (+18.4% from 2017)

Total number of genes with manual annotations: 7850 (+4.5% from 2017)

Table 1: Summary of C. elegans Manual Biological Process Annotations

Numbers refer to total number of annotations; annotations in parentheses represent annotations with extensions.

Annotation Group IMP IGI IDA ISS TAS IEP IPI IC NAS ISM ND IBA IKR HEP HMP HGI EXP
WormBase 8031 (454) 3208 (90) 1132 (33) 324 (1) 105 108 (11) 51 63 (10) 22 2 2 0 2 189 0 0 0
UniProt 3483 (831) 2694 (508) 218 (23) 209 29 (3) 23 2 (2) 4 101 0 66 0 0 0 0 0 0
SynGO 48 (37) 69 (44) 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10
CACAO 18 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
BHF-UCL 11 0 0 2 0 4 0 0 0 0 0 0 0 0 0 0 0
MGI 4 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0
HGNC 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0
GO_Central 2 0 0 0 0 0 0 0 0 0 0 12247 0 0 0 0 0
ParkinsonsUK-UCL 10 (4) 6 (3) 11 2 (1) 0 0 0 0 0 0 0 0 0 0 0 0 0
CAFA 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SGD 0 0 0 1 (1) 0 0 0 0 0 0 0 0 0 0 0 0 0
Totals 11344 (1206) 5556 (464) 1369 (55) 540 (2) 137 (3) 328 (18) 53 (2) 83 (10) 127 2 71 7530 1 18 (18) 135 (135)


Table 2: Summary of C. elegans Molecular Function Annotations

Numbers refer to total number of annotations; annotations in parentheses represent annotations with extensions.

Annotation Group IMP IGI IDA ISS TAS IPI IC NAS ISM ND IBA ISO IKR
WormBase 172 (11) 32 1899 (214) 643 (7) 33 1355 (5) 21 (1) 4 3 80 0 2 3
IntAct 0 0 0 0 0 2238 (60) 0 0 0 0 0 0 0
UniProt 117 (13) 26 185 (9) 231 (16) 24 (1) 511 (3) 123 50 0 123 0 0 0
CACAO 1 0 7 0 0 0 0 0 0 0 0 0 0
GO_Central 0 0 0 0 0 0 0 0 0 0 5957 0 1
HGNC 0 0 0 2 0 0 0 0 0 0 0 0 0
ParkinsonsUK-UCL 0 0 0 0 0 2 (2) 0 0 0 0 0 0 0
CAFA 1 0 0 0 0 1 0 0 0 0 0 0 0
Reactome 0 0 0 0 1 0 0 0 0 0 0 0 0
Totals 287 (22) 55 2067 (219) 853 (5) 70 (1) 4066 (66) 26 55 3 202 5957 2 3


Table 3: Summary of C. elegans Cellular Component Annotations

Numbers refer to total number of annotations; annotations in parentheses represent annotations with extensions.

Annotation Group IMP IGI IDA ISS TAS IPI IC NAS ISM ND IBA HDA EXP
WormBase 7 0 5622 (348) 379 27 140 (3) 49 7 4 12 0 545 (452) 0
GO_Central 0 0 0 0 0 0 0 0 0 0 6063
UniProt 80 (24) 1 742 (104) 219 20 1 16 47 0 116 0 0 0
MGI 0 0 16 0 0 0 0 0 0 0 0
HGNC 0 0 0 8 0 0 0 0 0 0 0
BHF-UCL 0 0 7 0 0 0 0 0 0 0 0
CACAO 0 0 3 0 0 0 0 0 0 0 0
Reactome 0 0 0 0 8 0 0 0 0 0 0
SynGO 29 0 89 (8) 1 (1) 0 0 0 0 0 0 0 2
Totals 81 (22) 1 7411 (898) 620 (1) 55 144 (3) 69 (1) 56 4 129 6063


Table 4: Summary of C. elegans Computational Annotations

Summary Statistics Based on WormBase Release WS262

Genes Stats:

 Genes with GO_term connections  13880 
   Non-IEA-only annotation             1170
   IEA-only annotation                 6290
   Both IEA and non-IEA annotations    6420

GO_term Stats:

 Distinct GO_terms connected to Genes   6023
   Associated by non-IEA only               3567
   Associated by IEA only                    817
   Associated by both IEA and non-IEA       1639
Type of Annotation IEA
Interpro2GO 21823
Other (e.g. Swiss-Prot keyword mapping) 44965