2018

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Annotation Progress

WormBase GO Annotation Statistics as of December 5, 2018

Manual annotation statistics are summarized in Tables 1 - 3.

Total number of unique manual annotations: 44384 (+3.8% from 2016)

Total number of genes with manual annotations: 7508 (-1.1% from 2016)

Table 1: Summary of C. elegans Manual Biological Process Annotations

Numbers refer to total number of annotations; annotations in parentheses represent annotations with extensions.

Annotation Group IMP IGI IDA ISS TAS IEP IPI IC NAS ISM ND IBA IKR HMP HGI
WormBase 8102 (451) 3215 (92) 1135 (33) 328 (1) 108 310 (18) 51 73 (10) 24 2 3 0 1 0 0
UniProt 3189 (751) 2331 (369) 212 (22) 203 29 (3) 14 2 (2) 5 103 0 68 0 0 18(18) 135 (135)
CACAO 20 1 3 0 0 0 0 0 0 0 0 0 0 0 0
BHF-UCL 11 0 0 2 0 4 0 0 0 0 0 0 0 0 0
MGI 4 0 6 0 0 0 0 0 0 0 0 0 0 0 0
HGNC 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0
GO_Central 2 0 0 0 0 0 0 0 0 0 0 7430 0 0 0
ParkinsonsUK-UCL 14 (4) 9 (3) 11 3 (1) 0 0 0 0 0 0 0 0 0 0 0
CAFA 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Totals 11344 (1206) 5556 (464) 1369 (55) 540 (2) 137 (3) 328 (18) 53 (2) 83 (10) 127 2 71 7530 1 18 (18) 135 (135)


Table 2: Summary of C. elegans Molecular Function Annotations

Numbers refer to total number of annotations; annotations in parentheses represent annotations with extensions.

Annotation Group IMP IGI IDA ISS TAS IPI IC NAS ISM ND IBA ISO IKR
WormBase 174 (11) 32 1895 (214) 653 (5) 45 1355 (5) 22 4 3 79 0 2 2
IntAct 0 0 0 0 0 2250 (56) 0 0 0 0 0 0 0
UniProt 111 (11) 23 165 (5) 198 24 (1) 458 (3) 4 51 0 123 0 0 0
CACAO 1 0 7 0 0 0 0 0 0 0 0 0 0
GO_Central 0 0 0 0 0 0 0 0 0 0 5957 0 1
HGNC 0 0 0 2 0 0 0 0 0 0 0 0 0
ParkinsonsUK-UCL 0 0 0 0 0 2 (2) 0 0 0 0 0 0 0
CAFA 1 0 0 0 0 1 0 0 0 0 0 0 0
Reactome 0 0 0 0 1 0 0 0 0 0 0 0 0
Totals 287 (22) 55 2067 (219) 853 (5) 70 (1) 4066 (66) 26 55 3 202 5957 2 3


Table 3: Summary of C. elegans Cellular Component Annotations

Numbers refer to total number of annotations; annotations in parentheses represent annotations with extensions.

Annotation Group IMP IGI IDA ISS TAS IPI IC NAS ISM ND IBA
WormBase 9 0 6674 (798) 386 27 143 (3) 50 (1) 7 4 12 0
GO_Central 0 0 0 0 0 0 0 0 0 0 6063
UniProt 72 (22) 1 711 (100) 233 20 1 19 49 0 117 0
MGI 0 0 16 0 0 0 0 0 0 0 0
HGNC 0 0 0 8 0 0 0 0 0 0 0
BHF-UCL 0 0 7 0 0 0 0 0 0 0 0
CACAO 0 0 3 0 0 0 0 0 0 0 0
Reactome 0 0 0 0 8 0 0 0 0 0 0
SynGO 0 0 0 1 (1) 0 0 0 0 0 0 0
Totals 81 (22) 1 7411 (898) 620 (1) 55 144 (3) 69 (1) 56 4 129 6063


Table 4: Summary of C. elegans Computational Annotations

Summary Statistics Based on WormBase Release WS262

Genes Stats:

 Genes with GO_term connections  13880 
   Non-IEA-only annotation             1170
   IEA-only annotation                 6290
   Both IEA and non-IEA annotations    6420

GO_term Stats:

 Distinct GO_terms connected to Genes   6023
   Associated by non-IEA only               3567
   Associated by IEA only                    817
   Associated by both IEA and non-IEA       1639
Type of Annotation IEA
Interpro2GO 21823
Other (e.g. Swiss-Prot keyword mapping) 44965