Difference between revisions of "2016 Advisory Board Meeting"

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* 1100 : Genomics
 
* 1100 : Genomics
 
** 1100-1125 - Integration and curation of hundreds of nematode genomes - Kevin
 
** 1100-1125 - Integration and curation of hundreds of nematode genomes - Kevin
** 1125-1145 - Curation and analysis of all nematode RNASeq gene expression data - Gary
+
** 1125-1145 - Curation and analysis of all C. elegans RNASeq gene expression data - Gary
 
** 1145-1210 - WormBase ParaSite - Bruce
 
** 1145-1210 - WormBase ParaSite - Bruce
 
** 1210-1245 - Discussion (+ specific questions for SAB)
 
** 1210-1245 - Discussion (+ specific questions for SAB)

Revision as of 16:55, 8 January 2016

The 2016 edition of the WormBase Scientific Advisory Board meeting will take place at Caltech on 4/5 Feb 2016.

Logistics

Attending

  • Hinxton
    • Paul Kersey, Matt Berriman, Kevin Howe, Bruce Bolt, Jane Lomax, Michael Paulini, Paul Davis, Gary Williams
  • OICR
    • Lincoln Stein, Todd Harris, Sibyl Gao, Adam Wright, Paulo Nuin

Travel

  • Hinxton
    • Will fly out on the 2nd of Feb, and return on Sun 7th Feb (cheap flights)
  • OICR
    • Arrive 3rd Feb, depart 6th Feb
  • Remote workers
    • Mary Ann - arrive 2nd Feb (evening), leave 7th Feb (evening)

Advisors


Discussion topics

Organisation of SAB talks

Agenda for the SAB itself will be organised into 4 main sections. Each section will have a short overview/scene-setting talk, followed by selected specfic talks. Each section will end with a time-tabled open discussion, which we should use to discuss strategy in that area, and put any specfic questions we have to the advisory board. Please add suggested questions/discussion topics for each section below.

  • Curation
    • How can we work with other MODs on curation strategy?
  • Genomics
    • How should we prioritise species for curation effort?
    • Would a community curation system for gene models be useful for nematodes?
    • Integration between WormBase and WB ParaSite - to what extent is this required?
  • User interface
    • How best to measure the utility of WormBase (and similar resources)?
    • What new tools / views should we have (e.g. enrichment tool, RNASeq querying)
  • Infrastructure and interoperability
    • How important is it that our infrastructure solution is reusable by other MODs (or genomics data management projects)
    • Is the amount of effort we invest in maintaining/extending wormMine typical for other *Mine deployments?
    • Is use of non-open-source software for core data management an acceptable risk?



Other potential talks (if we want/need to fill time)

  • Genome annotation curation - status and plans - Paul Davis
  • Documentation and outreach strategy - Todd
  • Integration and curation of the new B. malayi genome assembly v4 - Michael

Specific topics for project meeting / working groups

  • Cross-site communication
    • Unification of documentation and code; what are our standards for documentation? For code?
  • Database migration
    • Specific plans for the next 6-12 months
    • extending use to non-Caenorhabiditis sp
  • How to better integrate WormBase services (i.e. WB and WBPS)
    • Integrated search - what do we need to do to make this work?
    • Cross-site tools
      • Enrichment tool
      • Data mining
        • ParaSite has provision to replace BioMart with a system that supports "biologist friendly" queries, e.g. using set operation (a la EuPathDB, PomBase)
        • Is this on the InterMine road map?
        • If not, can we develop something that can be used in both WB and WBPS that complements (rather than competes with) WormMine?
  • Texpresso for parasitic worms
    • Discussions already started on this


Agenda (preliminary)

Wed 3rd Feb

  • 1400 : Project meeting (part one)

Thu 4th Feb

  • 0915-0930 - Introduction - Paul Sternberg
  • 0930 : Literature curation
    • 0930-0935 - Overview - status and priorities - Chris
    • 0935-0945 - Automation - doing more with less (SVMs and Automated gene descriptions) - Ranjana
    • 0945-0955 - Community curation - overview, status, tracking - Mary Ann & Chris
    • 0955-1005 - Micropublications - an incentive for community participation - Daniela
    • 1005-1015 - LEGO - Kimberly
    • 1015-1045 - Discussion (+ specific questions for SAB)
  • 1045 - 1100 : BREAK
  • 1100 : Genomics
    • 1100-1125 - Integration and curation of hundreds of nematode genomes - Kevin
    • 1125-1145 - Curation and analysis of all C. elegans RNASeq gene expression data - Gary
    • 1145-1210 - WormBase ParaSite - Bruce
    • 1210-1245 - Discussion (+ specific questions for SAB)
  • 1245-1345 : LUNCH
  • 1345 : User interface
    • 1345-1410 - WormBase web-site - usage, outreach etc - Todd
    • 1410-1420 - JBrowse - A new genome browser for WormBase
    • 1420-1430 - Visualisation of Ontology annotations (incl WOBr, SObA etc) - Raymond
    • 1430-1445 - WormMine - Paulo
    • 1445-1515 - Discussion (+ specific questions for SAB)
  • 1510-1530 : BREAK
  • 1530: Infrastructure and interoperability
    • 1530-1545 - Overview of current data management strategy and vision for future - Todd / Kevin
    • 1545-1605 - Database migration - status and roadmap - Adam
    • 1605-1615 - The InterMOD project and cross-MOD interoperability - Todd
    • 1615-1645 - Discussion (+ specific questions for SAB)

1645-1700 : BREAK

  • 1700: General discussion
    • Threat to NIH funding and alternative funding strategies
    • Working more closely with other MODs
    • How to make WormBase more useful / appealing to biomedical scientists

Fri 5th Feb

  • 0800-0900 : Advisors breakfast
  • 0900-1130 : Advisors report back to whole group
  • 1400-whenever : Project meeting (part two)