New 2012 Curation Status

Curation Status & Statistics Form (2012)

The live form (on Tazendra) can be found here

The sandbox/testing form can be found here

The CGI code is located on Tazendra/Mangolassi here:

/home/postgres/public_html/cgi-bin/curation_status.cgi

User Guide

Main Page

Above is a screenshot of the main page of the Curation Status Form. The user/curator is requested to identify who they wish to login as, and to select one of four options to continue:

1) Specific Paper Page - This is where the curator can specify one or more specific papers they wish to view curation status results for (see below). This page includes a Topic paper filter to search for papers related to a WormBase Biological Topic.

2) Add Results Page - This is where the curator can add curation status results for one or more specific papers (see below).

3) Curation Statistics Page - This is where the curator can view all curation statistics for ALL datatypes and ALL flagging methods (see below).

4) Curation Statistics Options Page - As an alternative to viewing the curation statistics for ALL datatypes and ALL flagging methods (as with option #3 above), this is where the curator can specify for which datatypes and flagging methods they would like to see curation statistics (see below).

Specific Paper Page

Above is a screenshot of the Specific Paper Page where a curator can specify which paper(s) they would like to view curation status results for. After typing/pasting in one or more WBPaper IDs in the paper entry field, the curator can specify which datatypes and flagging methods they would like to see results for. Note that selecting "all datatypes" will override any single datatype selections below. A curator can select what curation data sources they would like to see results for (i.e. Ontology Annotator and/or cur_curdata), flagging methods (SVM, AFP, CFP, STR[textpresso string matches]), the number of papers they would like to load at one time (default of 10), and whether they would like to see info (and links) for the PubMed ID (PMID), the PDF, and the paper's journal.

Once a curator clicks on "Get Results", they will be directed to the Detailed Results of Papers Page, where they can view the results of their query.

Papers can be listed as WBPaper### or simply as numbers, separated by spaces, commas, pipes, new lines, anything that is not a number. Any number that is entered will be considered a valid paper ID.

Recent addition as of November 2013 CG 11-6-2013 A Topic dropdown menu has been added to the "Specific Paper Page" so as to allow curators to view all papers related to a particular curation topic with respect to their data type. Note that selecting a Topic will look for overlap with any WBPaper IDs entered into the main paper entry field, only populating the form with papers associated with the Topic AND in the paper entry field. Topic papers will be pulled from the Topic Curation OA. If no papers are entered in the paper entry field AND no topic is selected, the form will return ALL papers (having undergone at least one flagging pipeline).

Add Results Page

Above is a screenshot of the Add Results Page of the form, where a curator can add new curation status results for one or more papers that they specify. A curator must specify what datatype they wish to submit paper results for and must specify what the status is for the paper(s): curated and (hence) positive, validated postive (but not yet curated), validated negative, or (if they need to revert back to not validated, or blank, status) not validated. The curator must then also specify at least one paper for which to apply this curation status in the paper entry field. Multiple papers must be entered as WBPaper### format and each on a separate line.

Optionally, a curator can select a pre-made comment from a drop down menu and/or enter a free-text comment. Once the curator clicks "Add Results", they will be directed to a New Results Summary Page:

If the results are overwriting existing results, they will be directed to an Overwrite Confirmation Page:

at which point the curator can confirm the overwrite of the previous results for the indicated paper and datatype, or simply go the main page (or go back a page to make corrections/edits). Note that the fields for which data has changed are highlighted in yellow for easy viewing. If the curator confirms the overwrite by checking the confirmation check box and clicking on "Overwrite Selected Results", they will be directed to the Overwrite Confirmation Summary Page:

A link is provided to go back to the main page of the form.

Main Curation Statistics Page

Above is a screenshot of a portion of the entire Curation Statistics table that a curator would be directed to from the main page of the form if they had clicked on the Curation Statistics Page button. Displayed at the top of the table are general paper statistics for a given datatype (datatypes indicated at the top of each column). Below that are statistics for papers that have been flagged (positive or negative) for the indicated datatype by ANY (at least one) flagging method. Below the "Any" statistics are the "Intersection" statistics, indicating papers flagged by ALL flagging methods for the indicated datatype. It should be emphasized here that "flagged" means processed by the flagging method, not necessarily flagged positive. Although not visible in the above screenshot, statistics for SVM results, AFP results, CFP results, and STR results are also included in this table.

The "Any", "Intersection", and individual flagging method sections of the table each follow a general template:

Flagged
   Flagged Positive
      Flagged Positive and Validated
         Flagged Positive, Validated False Positive
         Flagged Positive, Validated True Positive
            Flagged Positive, Validated True Positive, Curated
            Flagged Positive, Validated True Positive, Not Curated
      Flagged Positive, Not Validated
      Flagged Positive, Not Curated

and the individual flagging method sections additionally have a section for flagged negatives:

   Flagged Negative
      Flagged Negative and Validated
         Flagged Negative, Validated True Negative
         Flagged Negative, Validated False Negative
            Flagged Negative, Validated False Negative, Curated
            Flagged Negative, Validated False Negative, Not Curated
      Flagged Negative, Not Validated
      Flagged Negative, Not Curated

Each row title/header can be clicked on to bring up a small pop-up window with a brief description of what each title means. Each cell of the table has numbers indicating the number of papers that fit the criteria for that datatype and flag status, and the percentage (to two significant digits) that represents of a subset of some larger set. Each percentage is calculated, generally, as follows:

Flagged (% of curatable papers)
   Flagged Positive (% flagged)
      Flagged Positive and Validated (% flagged positive)
         Flagged Positive, Validated False Positive (% flagged positive and validated)
         Flagged Positive, Validated True Positive (% flagged positive and validated)
            Flagged Positive, Validated True Positive, Curated (% flagged positive and validated true positive)
            Flagged Positive, Validated True Positive, Not Curated (% flagged positive and validated true positive)
      Flagged Positive, Not Validated (% flagged positive)
      Flagged Positive, Not Curated (% flagged positive)

Each cell number (aside from the top three rows) is also a hyperlink to the Prepopulated Specific Papers Page, listing the paper IDs for each paper in the list, as well as providing options for the view of each of those papers in the Detailed Results of Papers Page.

NB: for STR data all the curatable papers are considered flagged. So the 'any flagged' number can be misleading. CAVEAT for when pulling out statistics.

Curation Statistics Page Display Info

The title/headers for each row are displayed at the left AND right sides of the table, to enable easier viewing when there are several datatypes being viewed at once. If the number of datatypes is restricted via the Curation Statistics Options Page, the titles/headers for each row will only display on both left and right sides of the table if more than six datatypes are selected for viewing (this was done to avoid overcrowding of the page when six or fewer datatypes/columns were visible).

The row-title column (leftmost column and, when more than six datatypes are visible, the rightmost column) are set to display at a fixed width of 600 pixels to allow all titles to fit on a single line. All other columns (datatype columns) are set to display at a fixed width of 120 pixels.

Curation Statistics Options Page

Above is a screenshot of the Curation Statistics Options Page, where a curator can specify what flagging methods and datatypes they would like to see curation statistics for. (Note 1) Loading a table with fewer datatypes or flagging methods is often much faster than loading the entire table. Whereas loading the entire table (with ALL datatypes and ALL flagging methods) takes roughly 23 seconds to load, loading a table with ALL flagging methods but ONE datatype will usually only take 1-3 seconds to load. (Note 2) If 6 or fewer datatypes are requested, the row titles/headers will only appear on the left side of the table; if more than 6 datatypes are viewed at once, the row titles/headers will appear on both the left AND the right sides of the table. (Note 3) The "Any" and "Intersection" rows of the resulting table will only show results for the flagging methods that you have selected to view. If only one flagging method is selected to view, the "Any" and "Intersection" rows will be identical to each other and to the "flagged positive" rows for the single flagging method.

Prepopulated Specific Papers Page

Above is a screenshot of the Prepopulated Specific Papers Page. Curators are directed here from any Curation Statistics table via the hyperlinked numbers in the statistics table. The entire list of paper IDs (that fit the criteria indicated in the table row/column of the statistics table) is listed as hyperlinks to the individual paper results (on the Detailed Results of Papers Page), as well as in the search box. Note that this page is identical to the Specific Paper Page, except that paper IDs are already pre-populated into the form from the statistics table.

An addition as of November 2013 is the Topic paper filtering drop down menu. The drop down menu provides a list of WormBase Biological Topics as read from the Topic Curation OA. If a topic is selected (e.g. 'Aging' in the example screenshot), the form will look for any papers that exist in BOTH the Topic paper list AND the list of papers entered into the paper entry field (in this case prepopulated from some prior filtering step). If there are no overlapping papers from both lists, the form will not return any papers. If a Topic is not selected, the form will simply return the papers as listed in the paper entry field. If no topic is selected AND there are no papers in the paper entry field, the form will return ALL papers (having undergone at least one flagging pipeline).

Detailed Results of Papers Page

Above is a screenshot of the Detailed Results of Papers Page, where curators can view and edit the curation status of individual papers as well as view the the flagging results of each flagging method for individual papers.

When ALL columns are visible:

the first column displays the WormBase paper ID (WBPaperID#);

the second column displays the name of the journal for the publication;

the third column lists the PubMed ID (PMID) and links out to the PubMed webpage for this article;

the fourth column displays the name of the PDF file stored locally on Tazendra with a hyperlink to the PDF file of the article in our local PDF archives;

the fifth column displays the datatype for that row (note that multiple datatypes may be displayed per paper, on separate rows);

the sixth, seventh, eighth, and ninth columns display the results of the flagging methods SVM, STR, CFP, and AFP, respectively;

the tenth column indicates the status of the paper in the Ontology Annotator (OA) for that datatype indicating "oa_blank" if the paper does not exist in the respective OA, or "curated" if the paper does exist in the respective OA, indicating that it has been curated (or at least partially curated); NOTE : A paper in the RNAi OA with every entry flagged with the "NO DUMP" toggle will appear as "oa_blank" in the Curation Status Form; a single row with a paper that does not have a "NO DUMP" toggle turned on will indicate a "curated" status in the Curation Status Form

the eleventh column provides a drop-down menu to select a curator (selecting a curator is only necessary if overwriting/changing the existing curator; the form recognizes what curator is logged in and automatically populates this field with the correct (logged in) curator if this field is blank);

the twelfth column provides a drop-down menu to select the "new result" for the paper, indicating whether it is "curated and positive", "validated positive", "validated negative", or "not validated" ("not validated" only needs to be selected when reverting back from "curated and positive", "validated positive", or "validated negative" entries that may have been entered accidentally; selecting this option will result in a blank field once the change has been submitted through the form)

the thirteenth column provides the drop-down menu of standard, premade comments

the fourteenth (and final) column is a free-text area where a curator can write in any pertinent notes about the curation status of this paper-datatype pair

If any new results for a paper are entered (in columns 10-13), the curator must click on the "Submit New Results" button at the bottom of the screen, at which point they will either be directed to the New Results Summary page or to the Overwrite Confirmation Page, as shown above in the Wiki section describing the Add Results Page. Note that in order for new paper result submissions to take effect, there must be a value in the "new results" column. Otherwise any comments (premade or free-text) will not be registered with the paper.

Conflicts

A paper that is found to have mutually exclusive flags triggers the papers to be flagged as a "conflict". These papers will not appear in any other lists (e.g. "curated", "validated", etc.) and need to be resolved before they enter back into a normal list. A conflict can be triggered if:

• A paper is found to be curated by the OA, but has been flagged, via the form, to be "validated negative". This raises a conflict which needs a curator to check if the curation is bogus or if the "validated negative" flag was a mistake. This can be resolved by changing the "validated negative" status to any other status ("not validated" (blank), "validated positive", or "curated and positive") if the paper was mistakenly flagged as "validated negative", OR by fixing the curation in the OA (delete bogus curation or fix the paper reference).

A paper will not be considered in conflict if the OA status indicates "oa blank" and is flagged as "curated and positive". This will be the case, for example, for all of the large scale papers whose annotations do not reside in the OA/Postgres.

Topic-Paper Filter

(In progress... CG 11-5-2013)

The Curation Status Form will now provide an option to filter a list of papers based on a WormBase Biological Topic. Official topics and affiliated papers are recognized from the "Topic" OA.

Code Documentation

Below is the documentation for the form's code, located on Tazendra (when live) or Mangolassi (sandbox):

/home/postgres/public_html/cgi-bin/curation_status.cgi

Specific Paper Page/ Prepopulated Specific Paper Page

The following code prints the "Specific Paper Page":

sub printSpecificPaperPage {
  &printFormOpen();
  &printHiddenCurator();
  &printTextareaSpecificPapers('');
  &printSelectTopics();
  &printCheckboxesDatatype('off');
  &printCheckboxesCurationSources('all');
  &printPaperOptions();
  &printSubmitGetResults();
  &printFormClose();
} # sub printSpecificPaperPage

The following code prints the "Prepopulated Specific Papers Page":

sub listCurationStatisticsPapersPage {
  &printFormOpen();
  &printHiddenCurator();
  my ($papers) = &printListCurationStatisticsPapers();
  &printTextareaSpecificPapers($papers);
  &printSelectTopics();
  &printSubmitGetResults();
  ($oop, my $listDatatype) = &getHtmlVar($query, "listDatatype");
  &printCheckboxesDatatype($listDatatype);
  &printCheckboxesCurationSources('all');
  &printPaperOptions();
  &printSubmitGetResults();
  &printFormClose();
} # sub listCurationStatisticsPapersPage

Paper-Topic Filter

On both the Specific Paper Page and the Prepopulated Specific Papers Page, we have the option to filter the papers listed in the WBPaper ID field based on their affiliation to a particular WormBase Biological Topic, as informed by the Topic Curation OA.

The following code is responsible for displaying the drop down menu of Topics:

sub printSelectTopics {
  print qq(Filter papers from list through a topic :<br/>);
  print qq(<select name="select_topic">);
  print qq(<option value="none">no topic, use all papers from textarea above</option>\n);
  my %topicIDs; my %topicIdToName;
  $result = $dbh->prepare( "SELECT DISTINCT(pro_process.pro_process) FROM pro_process, pro_paper, pro_topicpaperstatus WHERE pro_process.joinkey = pro_paper.joinkey AND pro_process.joinkey = pro_topicpaperstatus.joinkey AND (pro_topicpaperstatus.pro_topicpaperstatus = 'relevant') ORDER BY pro_process.pro_process" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) { $topicIDs{$row[0]}++; }
  my $topicIDs = join"','", sort keys %topicIDs;                # for all the topicIDs, get the name from the prt_processname
  $result = $dbh->prepare( "SELECT prt_processid.prt_processid, prt_processname.prt_processname FROM prt_processid, prt_processname WHERE prt_processid.joinkey = prt_processname.joinkey AND prt_processid.prt_processid IN ('$topicIDs')" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) { $topicIdToName{$row[0]} = $row[1]; }    # map wbprocess ids to their names for dropdown display
  foreach my $topic (sort keys %topicIdToName) { print qq(<option value="$topic $topicIdToName{$topic}">$topic $topicIdToName{$topic}</option>); }
  print qq(</select><br/>);
} # sub printSelectTopics

The above code incorporates two Postgres queries:

First, gets the WBProcessIDs that are in the topic curation OA and have a paper and the status is 'relevant':

SELECT DISTINCT(pro_process.pro_process) FROM pro_process, pro_paper, pro_topicpaperstatus WHERE pro_process.joinkey = pro_paper.joinkey AND pro_process.joinkey = pro_topicpaperstatus.joinkey AND (pro_topicpaperstatus.pro_topicpaperstatus = 'relevant') ORDER BY pro_process.pro_process

Second, the WBProcess IDs go into the variable $topic, and for each of those WBProcess IDs we get the corresponding name from the process Term OA:

SELECT prt_processid.prt_processid, prt_processname.prt_processname FROM prt_processid, prt_processname WHERE prt_processid.joinkey = prt_processname.joinkey AND prt_processid.prt_processid IN ('$topicIDs')

then we have a dropdown of process IDs ordered by ID, with the human readable process name next to it

Add Results Page: Loading Page and Processing Input

The following code is responsible for printing the Add Results Page:

sub printAddResultsPage {
  &printAddSection('', '', '', '', '', '', '');
} # sub printAddResultsPage

This code defines the printAddResultsPage subroutine which in turn calls upon the printAddSection subroutine (see below), passing it empty strings, declaring empty/initialized values for the curator ($twonumForm), datatype ($datatypeForm), validation result ($donposnegForm), paper list ($paperResultsForm), premade comment ($selcommentForm), and free-text comment ($txtcommentForm). Once data is submitted, these variables acquire values and are reported in the event of an error.

printAddSection Subroutine

The following code defines the printAddSection subroutine mentioned above, which adds the form components for entering datatype, validation status, paper IDs, premade comments, and free-text comments:

sub printAddSection {
  my ($twonumForm, $datatypeForm, $donposnegForm, $paperResultsForm, $selcommentForm, $txtcommentForm) = @_;
  my $selected = '';
  &printFormOpen();
  &printHiddenCurator();
  print qq(Select your datatype :<br/>);
  print qq(<select name="select_datatype">);
  print qq(<option value=""             ></option>\n);
  foreach my $datatype (keys %datatypes) {
    if ($datatype eq $datatypeForm) { $selected = qq(selected="selected"); } else { $selected = ''; }
    print qq(<option value="$datatype" $selected>$datatype</option>\n); }
  print qq(</select><br/>);
  print qq(Select if the data is positive or negative :<br/>);
  my $select_size = scalar keys %donPosNegOptions;
  print qq(<select name="select_donposneg" size="$select_size">);
  foreach my $donposnegValue (keys %donPosNegOptions) {
    if ($donposnegForm eq $donposnegValue) { $selected = qq(selected="selected"); } else { $selected = ''; }
    print qq(<option value="$donposnegValue" $selected>$donPosNegOptions{$donposnegValue}</option>\n); }
  print qq(</select><br/>);
  print qq(Enter paper data here in the format "WBPaper00001234" (paper as a whole) with separate papers in separate lines.<br/>);
  print qq(<textarea name="textarea_paper_results" rows="6" cols="80">$paperResultsForm</textarea><br/>\n);
  print qq(Select your comment (optional) :<br/>);
  print qq(<select name="select_comment">);
  print qq(<option value=""             ></option>\n);
  foreach my $comment (keys %premadeComments) {
    if ($comment eq $selcommentForm) { $selected = qq(selected="selected"); } else { $selected = ''; }
    print qq(<option value="$comment" $selected>$premadeComments{$comment}</option>\n); }
  print qq(</select><br/>);
  print qq(Enter a free text comment to associate with all papers above (optional) :<br/>);
  print qq(<textarea rows="4" cols="80" name="textarea_comment">$txtcommentForm</textarea><br/>);
  print qq(<input type="submit" name="action" value="Add Results"><br/>\n);
  &printFormClose();
} # sub printAddSection

addResults Subroutine

When a curator clicks on "Add Results" on the Add Results Page, the following code will process the curator's input, catching errors when they arise:

sub addResults {
  &printFormOpen();
  &printHiddenCurator();
  my $errorData = '';
  my %papersToAdd;
  my $twonum = $curator;
  ($oop, my $datatype) = &getHtmlVar($query, "select_datatype");
  unless ($datatype) { $errorData .= "Error : Need to select a datatype.<br/>\n"; }
  ($oop, my $donposneg) = &getHtmlVar($query, "select_donposneg");
  unless ($donposneg) { $errorData .= "Error : Need to select whether result is curated, validated positive, or validated negative.<br/>\n"; }
  ($oop, my $paperResults) = &getHtmlVar($query, "textarea_paper_results");
  if ($paperResults) {
      my @lines = split/\r\n/, $paperResults;
      foreach my $line (@lines) {
        if ($line =~ m/^WBPaper(\S+)$/) { $papersToAdd{$1}++; }
         else { $errorData .= qq(Error bad line : ${line}<br/>\n); }
      } } # foreach my $line (@lines)
    else { $errorData .= "Error : Need to enter at least one paper.<br/>\n"; }
  ($oop, my $selcomment) = &getHtmlVar($query, "select_comment");
  ($oop, my $txtcomment) = &getHtmlVar($query, "textarea_comment");
  if ($errorData) {                             # problem with data, do not allow creation of any data, show form again
      print "$errorData<br />\n";
      printAddSection($twonum, $datatype, $donposneg, $paperResults, $selcomment, $txtcomment); }
    else {                                      # all data is okay, enter data.
      my $joinkeys = join"','", sort keys %papersToAdd;
      my ($pgDataRef) = &getPgDataForJoinkeys($joinkeys, $datatype);
      my %pgData = %$pgDataRef;

      my @data; my @duplicateData;
      foreach my $joinkey (sort keys %papersToAdd) {
          my @line;
          push @line, $joinkey;
          push @line, $datatype;
          push @line, $twonum;
          push @line, $donposneg;
          push @line, $selcomment;
          push @line, $txtcomment;
          if ($pgData{$joinkey}{$datatype}) { push @duplicateData, \@line; }
            else { push @data, \@line; }
      } # foreach my $joinkey (sort keys %papersToAdd)
      &processResultDataDuplicateData(\@data, \@duplicateData, \%pgData);
    } # else # if ($errorData)
  &printFormClose();
} # sub addResults

This code (above) will check to ensure the following:

1) A datatype has been selected

2) A validation status has been entered

3) At least one paper ID has been submitted

4) There is only one paper ID per line

5) The paper IDs entered are in the format 'WBPaper########'

Any exceptions to these will result in an error message printed to the screen, in addition to reprinting the screen with the submitted values in there respective fields.

If no errors are found, the script will continue by calling on the getPgDataForJoinkeys subroutine (to query Postgres for the cur_curdata associated with each paper-datatype pair; see below) and writing the new input values to the appropriate paper-datatype pairs.

sub getPgDataForJoinkeys {
  my ($joinkeys, $datatype) = @_;
  my %pgData;
  $result = $dbh->prepare( "SELECT * FROM cur_curdata WHERE cur_datatype = '$datatype' AND cur_paper IN ('$joinkeys')" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) {
    $pgData{$row[0]}{$row[1]}{curator}     = $row[2];
    $pgData{$row[0]}{$row[1]}{donposneg}   = $row[3];
    $pgData{$row[0]}{$row[1]}{selcomment}  = $row[4];
    $pgData{$row[0]}{$row[1]}{txtcomment}  = $row[5];
    $pgData{$row[0]}{$row[1]}{timestamp}   = $row[6]; }
  return \%pgData;
} # sub getPgDataForJoinkeys

processResultDataDuplicateData Subroutine

The code will then run the processResultDataDuplicateData subroutine (see below) to print the results to the screen as the New Results Summary Page (for new data) and/or handle the overwrite confirmation when data needs to be overwritten, generating the Overwrite Confirmation Page (see Add Results Page section above).

sub processResultDataDuplicateData {
  my ($dataRef, $duplicateDataRef, $pgDataRef) = @_;
  my @data          = @$dataRef;
  my @duplicateData = @$duplicateDataRef;
  my %pgData        = %$pgDataRef;
  print qq(<table border="1">\n);
  print qq(<tr>${thDot}paperId</td>${thDot}datatype</td>${thDot}curator</td>${thDot}value</td>${thDot}selcomment</td>${thDot}textcomment</td></tr>\n);
  foreach my $lineRef (@data) {
    my @line = @$lineRef;
    foreach (@line) { unless ($_) { $_ = ''; } }        # initialize values if none are there
    my $pgvalues = join"','", @line;
    my @pgcommands = ();
    my $pgcommand = "INSERT INTO cur_curdata VALUES ('$pgvalues');";
    push @pgcommands, $pgcommand;
    $pgcommand = "INSERT INTO cur_curdata_hst VALUES ('$pgvalues');";
    push @pgcommands, $pgcommand;
    foreach my $pgcommand (@pgcommands) {
      print qq($pgcommand<br/>\n);
# UNCOMMENT TO POPULATE
      $dbh->do( $pgcommand );
    }
    my $trData = join"</td>$tdDot", @line;
    print qq(<tr>${tdDot}$trData</td></tr>\n);
  } # foreach my $lineRef (@data)
  print qq(</table>\n);
  if (scalar @data > 0) { print "results added<br />\n"; }

The first section of the subroutine (above) processes all data submitted through the Add Results Page that is not overwriting any existing data. The new data is submitted to Postgres and a table is printed to the screen as the New Results Summary Page.

The next sections of the subroutine handle new results that will overwrite existing Postgres values for the paper-datatype pairs. First, the code determines what data already exists in Postgres for a given paper-datatype pair and stores these in $xxxxxPg variables. Then, the code determines what values for curator, validation status, premade comment, and free-text comment were submitted through the form and stores these in $xxxxxFm variables. Next, the code generates and displays a table for each paper-datatype pair that has values being overwritten (if the corresponding $xxxxxPg and $xxxxxFm variables are not equal) with each set of data (old and new) highlighted in yellow to draw attention to these for overwrite confirmation. A confirmation checkbox is displayed for each paper-datatype pair undergoing an overwrite.

  my $overwriteCount = 0;
  foreach my $lineRef (@duplicateData) {                # for data already in postgres, add option to overwrite
    my @line = @$lineRef;
    foreach (@line) { unless ($_) { $_ = ''; } }        # initialize values if none are there
    my ( $joinkey, $datatype, $twonum, $donposneg, $selcomment, $txtcomment ) = @line;
    my ( $curatorPg, $curatorPgName, $donposnegPg, $selcommentPg, $selcommentPgText, $txtcommentPg, $timestampPg ) = ( ' ', ' ', ' ', ' ', ' ', ' ', ' ' );
    my ( $curatorFm, $curatorFmName, $donposnegFm, $selcommentFm, $selcommentFmText, $txtcommentFm, $timestampFm ) = ( ' ', ' ', ' ', ' ', ' ', ' ', '<td> </td>' );
    if ( $pgData{$joinkey}{$datatype}{curator}    ) { $curatorPg    = $pgData{$joinkey}{$datatype}{curator};    $curatorPgName = $curators{$curatorPg}; }
    if ( $pgData{$joinkey}{$datatype}{donposneg}  ) { $donposnegPg  = $pgData{$joinkey}{$datatype}{donposneg};  }
    if ( $pgData{$joinkey}{$datatype}{selcomment} ) { $selcommentPg = $pgData{$joinkey}{$datatype}{selcomment}; $selcommentPgText = $premadeComments{$selcommentPg}; }
    if ( $pgData{$joinkey}{$datatype}{txtcomment} ) { $txtcommentPg = $pgData{$joinkey}{$datatype}{txtcomment}; }
    if ( $pgData{$joinkey}{$datatype}{timestamp}  ) { $timestampPg  = "<td>$pgData{$joinkey}{$datatype}{timestamp};</td>"  }
    if ( $twonum ) { $curatorFm = $twonum;
      if ( $curators{$curatorFm} ) { $curatorFmName   = $curators{$curatorFm}; } }
    if ( $donposneg )         { $donposnegFm = $donposneg; }
    if ( $selcomment ) { $selcommentFm = $selcomment;
      if ( $premadeComments{$selcommentFm} ) { $selcommentFmText = $premadeComments{$selcommentFm}; } }
    if ( $txtcomment ) { $txtcommentFm = $txtcomment; }
    my $isDifferent = 0;                                # if any of the non-key values has changed, show option to overwrite
    if ($curatorFmName    ne $curatorPgName) {
        $isDifferent++;
        $curatorFmName = '<td style="background-color:yellow">' . $curatorFmName . '</td>';
        $curatorPgName = '<td style="background-color:yellow">' . $curatorPgName . '</td>'; }
      else {
        $curatorFmName = '<td>' . $curatorFmName . '</td>';
        $curatorPgName = '<td>' . $curatorPgName . '</td>'; }
    if ($donposnegFm  ne $donposnegPg) {
        $isDifferent++;
        $donposnegFm = '<td style="background-color:yellow">' . $donposnegFm . '</td>';
        $donposnegPg = '<td style="background-color:yellow">' . $donposnegPg . '</td>'; }
      else {
        $donposnegFm = '<td>' . $donposnegFm . '</td>';
        $donposnegPg = '<td>' . $donposnegPg . '</td>'; }
    if ($selcommentFmText ne $selcommentPgText) {
        $isDifferent++;
        $selcommentFmText = '<td style="background-color:yellow">' . $selcommentFmText . '</td>';
        $selcommentPgText = '<td style="background-color:yellow">' . $selcommentPgText . '</td>'; }
      else {
        $selcommentFmText = '<td>' . $selcommentFmText . '</td>';
        $selcommentPgText = '<td>' . $selcommentPgText . '</td>'; }
    if ($txtcommentFm ne $txtcommentPg) {
        $isDifferent++;
        $txtcommentFm = '<td style="background-color:yellow">' . $txtcommentFm . '</td>';
        $txtcommentPg = '<td style="background-color:yellow">' . $txtcommentPg . '</td>'; }
      else {
        $txtcommentFm = '<td>' . $txtcommentFm . '</td>';
        $txtcommentPg = '<td>' . $txtcommentPg . '</td>'; }
    next unless ($isDifferent > 0);
    $overwriteCount++;
    print qq(<input type="hidden" name="joinkey_$overwriteCount"       value="$joinkey"  >);
    print qq(<input type="hidden" name="datatype_$overwriteCount"      value="$datatype" >);
    print qq(<input type="hidden" name="twonum_$overwriteCount"        value="$twonum"   >);
    print qq(<input type="hidden" name="donposneg_$overwriteCount"     value="$donposneg"   >);
    print qq(<input type="hidden" name="selcomment_$overwriteCount"    value="$selcomment"  >);
    print qq(<input type="hidden" name="txtcomment_$overwriteCount"    value="$txtcomment"  >);
    print qq(WBPaper$joinkey $datatype : <br/>\n);
    print qq(<table border="1">\n);
    print qq(<tr><th> </th><th>curator</th><th>value</th><th>selcomment</th><th>txtcomment</th><th>timestamp</th></tr>);
    print qq(<tr><td>old</td>${curatorPgName}${donposnegPg}${selcommentPgText}${txtcommentPg}${timestampPg}</tr>\n);
    print qq(<tr><td>new</td>${curatorFmName}${donposnegFm}${selcommentFmText}${txtcommentFm}${timestampFm}</tr>\n);
    print qq(</table>\n);
    print qq(Confirm change <input type="checkbox" name="checkbox_$overwriteCount" value="overwrite"><br/><br/>\n);
  } # foreach my $lineRef (@data)
  if ($overwriteCount > 0) {
    print qq(<input type="hidden" name="overwrite_count" value="$overwriteCount">);
    print qq(<input type="submit" name="action" value="Overwrite Selected Results"><br/>\n); }
} # sub processResultDataDuplicateData

Once the curator has confirmed the overwrite of the relevant results and clicked on the "Overwrite Selected Results", the overwriteSelectedResults subroutine (below) will run to officially overwrite the data in the Postgres cur_curdata table.

sub overwriteSelectedResults {
  ($oop, my $overwriteCount) = &getHtmlVar($query, "overwrite_count");
  my @pgcommands;
  for my $i (1 .. $overwriteCount) {
    ($oop, my $overwrite) = &getHtmlVar($query, "checkbox_$i");
    next unless ($overwrite eq 'overwrite');
    ($oop, my $joinkey    ) = &getHtmlVar($query, "joinkey_$i"    );
    ($oop, my $datatype   ) = &getHtmlVar($query, "datatype_$i"   );
    ($oop, my $twonum     ) = &getHtmlVar($query, "twonum_$i"     );
    ($oop, my $donposneg  ) = &getHtmlVar($query, "donposneg_$i"  );
    ($oop, my $selcomment ) = &getHtmlVar($query, "selcomment_$i" );
    ($oop, my $txtcomment ) = &getHtmlVar($query, "txtcomment_$i" );
    unless ($donposneg) { $donposneg = ''; } unless ($selcomment) { $selcomment = ''; } unless ($txtcomment) { $txtcomment = ''; }
    push @pgcommands, qq(DELETE FROM cur_curdata WHERE cur_paper = '$joinkey' AND cur_datatype = '$datatype' AND cur_curator = '$twonum');
    push @pgcommands, qq(INSERT INTO cur_curdata VALUES ('$joinkey', '$datatype', '$twonum', '$donposneg', '$selcomment', '$txtcomment'));
    push @pgcommands, qq(INSERT INTO cur_curdata_hst VALUES ('$joinkey', '$datatype', '$twonum', '$donposneg', '$selcomment', '$txtcomment'));
  } # for my $i (1 .. $overwriteCount)
  foreach my $pgcommand (@pgcommands) {
    print "$pgcommand<br />\n";
# UNCOMMENT TO POPULATE
    $dbh->do( $pgcommand );
  } # foreach my $pgcommand (@pgcommands)
} # sub overwriteSelectedResults

Detailed Results of Papers Page: Loading Data (the getResults Subroutine)

The following code is for the getResults subroutine which displays the Detailed Results of Papers Page after receiving input from the curator about what to display (from a Specific Paper Page or Prepopulated Specific Papers Page submission).

The first section of code collects all curatable papers, processes the checkbox input for the various datatypes, and processes the paper IDs that were submitted in the paper field.

sub getResults {
  &printFormOpen();
  &printHiddenCurator();
  &populateCuratablePapers();                   # assume for now that we only care about curatable papers

  ($oop, my $all_datatypes_checkbox) = &getHtmlVar($query, "checkbox_all_datatypes");
  unless ($all_datatypes_checkbox) { $all_datatypes_checkbox = ''; }
  foreach my $datatype (keys %datatypes) {
    ($oop, my $chosen) = &getHtmlVar($query, "checkbox_$datatype");
    unless ($chosen) { $chosen = ''; }
    if ($all_datatypes_checkbox eq 'all') { $chosen = $datatype; }      # if all datatypes checkbox was selected, set that datatype's chosen to that datatype
    print qq(<input type="hidden" name="checkbox_$datatype" value="$chosen">\n);
    if ($chosen) { $chosenDatatypes{$chosen}++; }
  } # foreach my $datatype (keys %datatypes)

  ($oop, my $specificPapers) = &getHtmlVar($query, "specific_papers");
  my %filterPapers; my %specificPapers; my %topicPapers;
  if ($specificPapers) { my (@joinkeys) = $specificPapers =~ m/(\d+)/g; foreach (@joinkeys) { $specificPapers{$_}++; } }
  ($oop, my $topic)          = &getHtmlVar($query, "select_topic");     # if there's a selected topic replace specific papers with those from topic
  unless ($topic) { $topic = 'none'; }
  if ($topic ne 'none') {
    print "using topic $topic<br/>\n";
    my ($topicID) = $topic =~ m/(WBbiopr:\d+)/;                         # get the WBProcessID from the topic which includes the name
    print qq(<input type="hidden" name="select_topic" value="$topic">\n);
    $result = $dbh->prepare( "SELECT DISTINCT(pro_paper.pro_paper) FROM pro_process, pro_paper, pro_topicpaperstatus WHERE pro_process.joinkey = pro_paper.joinkey AND pro_process.joinkey = pro_topicpaperstatus.joinkey AND (pro_topicpaperstatus.pro_topicpaperstatus = 'relevant') AND pro_process.pro_process = '$topicID'" );
    $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
    while (my @row = $result->fetchrow) { $row[0] =~ s/WBPaper//; $topicPapers{$row[0]}++; }
  } # if ($topic ne 'none')
  if ($specificPapers && ($topic ne 'none')) {
      foreach (sort keys %specificPapers) { if ($topicPapers{$_}) { $chosenPapers{$_}++; } } }
    elsif ($specificPapers) {
      foreach (sort keys %specificPapers) { $chosenPapers{$_}++; } }
    elsif ($topic ne 'none') {
      foreach (sort keys %topicPapers) { $chosenPapers{$_}++; } }
    else { $chosenPapers{'all'}++; }  
  print qq(<input type="hidden" name="specific_papers" value="$specificPapers">\n);

The above code looks at the Topic Curation OA for rows where a paper matches the selected topic, the status is 'relevant', and gets the associated WBPapers

How filtering works: There are two lists of papers: (1) papers in the text area box, (2) papers for the topic (from the Topic Curation OA) The filtering code looks for papers that exist in both lists and generates results to display for the filtered list of papers. If no papers are entered in the text area, the resulting list of papers will be whatever papers are affiliated with the Topic. If there are no papers affiliated with the topic, the resulting list will be whatever papers were entered into the paper text area. If there are no papers in either the text area or affiliated with the Topic, it will return all papers relevant to this form.

The next section of code populates cur_curdata for the respective paper-datatype pairs given the input from above. The code takes into account whether to show OA data and what flagging methods to display for each paper-datatype pair, to prepare them for display. Additionally, the code is now processing how many papers to display per page, setting the default page (if multiple pages of results) to see page "0", and determining whether or not the curator wishes to see the journal, PMID, and/or PDF links for each paper.

  &populateCurCurData();                                # always show curator values since they have to be editable

  ($oop, my $displayOa)  = &getHtmlVar($query, "checkbox_oa");    unless ($displayOa) {  $displayOa  = ''; }
  ($oop, my $displayCfp) = &getHtmlVar($query, "checkbox_cfp");   unless ($displayCfp) { $displayCfp = ''; }
  ($oop, my $displayAfp) = &getHtmlVar($query, "checkbox_afp");   unless ($displayAfp) { $displayAfp = ''; }
  ($oop, my $displaySvm) = &getHtmlVar($query, "checkbox_svm");   unless ($displaySvm) { $displaySvm = ''; }
  ($oop, my $displayStr) = &getHtmlVar($query, "checkbox_str");   unless ($displayStr) { $displayStr = ''; }
  print qq(<input type="hidden" name="checkbox_oa"  value="$displayOa" >\n);
  print qq(<input type="hidden" name="checkbox_cfp" value="$displayCfp">\n);
  print qq(<input type="hidden" name="checkbox_afp" value="$displayAfp">\n);
  print qq(<input type="hidden" name="checkbox_svm" value="$displaySvm">\n);
  print qq(<input type="hidden" name="checkbox_str" value="$displayStr">\n);
  if ($displayOa) {  &populateOaData();  }
  if ($displayCfp) { &populateCfpData(); }
  if ($displayAfp) { &populateAfpData(); }
  if ($displaySvm) { &populateSvmData(); }
  if ($displayStr) { &populateStrData(); }

  ($oop, my $showJournal) = &getHtmlVar($query, "checkbox_journal");   unless ($showJournal) { $showJournal = ''; }
  ($oop, my $showPmid)    = &getHtmlVar($query, "checkbox_pmid");      unless ($showPmid) {    $showPmid = '';    }
  ($oop, my $showPdf)     = &getHtmlVar($query, "checkbox_pdf");       unless ($showPdf) {     $showPdf = '';     }
  print qq(<input type="hidden" name="checkbox_journal" value="$showJournal">\n);
  print qq(<input type="hidden" name="checkbox_pmid"    value="$showPmid">\n);
  print qq(<input type="hidden" name="checkbox_pdf"     value="$showPdf">\n);

  ($oop, my $papersPerPage) = &getHtmlVar($query, "papers_per_page");
  ($oop, my $pageSelected)  = &getHtmlVar($query, "select_page");
  unless ($papersPerPage) { $papersPerPage = 10; }
  unless ($pageSelected) {  $pageSelected  = 0;  }
  print qq(<input type="hidden" name="papers_per_page" value="$papersPerPage">\n);

  my @headerRow = qw( paperID );
  if ($showJournal) { push @headerRow, "journal"; &populateJournal(); }
  if ($showPmid)    { push @headerRow, "pmid";    &populatePmid();    }
  if ($showPdf)     { push @headerRow, "pdf";     &populatePdf();     }

The code now generates a hash (%trs) of rows of results (not necessarily in the order submitted). Any paper that has data for the relevant datatype and flagging method, this data is then loaded into the appropriate column of each row. For each paper submitted and each datatype requested, the code will load the flagging results, cur_curdata, and OA (curation) data into the %allPaperData hash table. The code then loads, for each paper queried and datatype requested, the relevant results. The first column for any paper will display the WBPaper ID#. If the PMID, journal, and/or PDF link were requested to be displayed, they are displayed in the next columns for a given paper. Next is displayed the datatype column. In the next column (if SVM data was requested for view), the SVM data for the each paper-datatype pair for the paper are populated into the table, highlighting the "high", "medium", and "low" SVM results in decreasing intensities of red highlight, respectively. The next columns are populated with STR, CFP, AFP, and OA data (if requested) for each paper-datatype pair. Note that a blank field for STR, CFP and AFP are simply blank ("") whereas an empty result for OA data is represented by "oa_blank". Otherwise, the STR, CFP and AFP fields would be populated with free-text entries from the STR, CFP and AFP results and the OA field would indicate "curated" if data was found in the OA for the paper-datatype pair. In the next columns are displayed the curator drop-down menu, the validation status drop-down menu, the premade comment drop-down menu, and the free-text comment field. Any new results submitted via this page for a paper-datatype pair will automatically be attributed to the curator that is logged in, unless their is already a curator listed in the curator field or the curator explicitly selects a curator from the curator drop-down list. In the free-text comment field, if there are more than 20 characters stored, only the first 20 characters will be displayed followed by an ellipsis ("..."). Clicking inside the free-text field will open up the full view of the text and while editing will remain in full text view. Subsequent clicking outside of the text field will revert back to the truncated, ellipsis view to conserve screen space. Each cell in the table is outlined with a dotted line format.

  my %trs;                              # td data for each table row
  my %paperPosNegOkay;                  # papers that have positive-negative data okay, so show all svm results for that paper even if a given row isn't positive-negative okay
  my %paperInfo;                        # for a joinkey, all the paper information about it to show in a big rowspan for that table row

  my %allPaperData;                     # hash of datatype - joinkey  for all posible queried data structures, to key off from this when there are no svm results for a data structure with data.
  foreach my $datatype (keys %svmData) { foreach my $joinkey (keys %{ $svmData{$datatype} }) { $allPaperData{$joinkey}{$datatype}++; } }
  foreach my $datatype (keys %strData) { foreach my $joinkey (keys %{ $strData{$datatype} }) { $allPaperData{$joinkey}{$datatype}++; } }
  foreach my $datatype (keys %curData) { foreach my $joinkey (keys %{ $curData{$datatype} }) { $allPaperData{$joinkey}{$datatype}++; } }
  foreach my $datatype (keys %oaData)  { foreach my $joinkey (keys %{  $oaData{$datatype} }) { $allPaperData{$joinkey}{$datatype}++; } }
  foreach my $datatype (keys %cfpData) { foreach my $joinkey (keys %{ $cfpData{$datatype} }) { $allPaperData{$joinkey}{$datatype}++; } }
  foreach my $datatype (keys %afpData) { foreach my $joinkey (keys %{ $afpData{$datatype} }) { $allPaperData{$joinkey}{$datatype}++; } }

  my $trCounter = 0;
  foreach my $joinkey (sort keys %curatablePapers) {                    # TODO curatablePapers or allPaperData that have some flag ?
    next unless ($chosenPapers{$joinkey} || $chosenPapers{all});

    push @{ $paperInfo{$joinkey} }, $joinkey;
    my $journal = ''; my $pmid = ''; my $pdf = ''; my $primaryData = '';
    if ($showJournal) {
      if ($journal{$joinkey}) { $journal = $journal{$joinkey}; }
      push @{ $paperInfo{$joinkey} }, $journal; }
    if ($showPmid) {
      if ($pmid{$joinkey}) { $pmid = $pmid{$joinkey}; }
      push @{ $paperInfo{$joinkey} }, $pmid; }
    if ($showPdf) {
      if ($pdf{$joinkey}) { $pdf = $pdf{$joinkey}; }
      push @{ $paperInfo{$joinkey} }, $pdf; }

    foreach my $datatype (sort keys %{ $allPaperData{$joinkey} }) {
      next unless ($chosenDatatypes{$datatype});                        # show only results for selected datatype
      my @dataRow = ( "$datatype" );
      $trCounter++;
      if ($displaySvm) {
        my $svmResult = '';
        if ($svmData{$datatype}{$joinkey}) { $svmResult = $svmData{$datatype}{$joinkey}; }
        my $bgcolor = 'white';
        if ($svmResult eq 'high')      { $bgcolor = '#FFA0A0'; }
        elsif ($svmResult eq 'medium') { $bgcolor = '#FFC8C8'; }
        elsif ($svmResult eq 'low')    { $bgcolor = '#FFE0E0'; }
        $svmResult = qq(<span style="background-color: $bgcolor">$svmResult</span>);
        push @dataRow, $svmResult;
      } # if ($displaySvm)
      
      if ($displayStr) {
        my $strResult = '';
        if ($strData{$datatype}{$joinkey}) { $strResult = $strData{$datatype}{$joinkey}; }
        push @dataRow, $strResult;
      }

      if ($displayCfp) {
        my $cfpResult = '';
        if ($cfpData{$datatype}{$joinkey}) { $cfpResult = $cfpData{$datatype}{$joinkey}; }
        push @dataRow, $cfpResult;
      }

      if ($displayAfp) {
        my $afpResult = '';
        if ($afpData{$datatype}{$joinkey}) { $afpResult = $afpData{$datatype}{$joinkey}; }
        push @dataRow, $afpResult;
      }

      if ($displayOa) {
        my $oaResult = 'oa_blank';
        if ($oaData{$datatype}{$joinkey}) { $oaResult = $oaData{$datatype}{$joinkey}; }
        push @dataRow, $oaResult;
      }

      my $thisCurator = '';                                                     # curator in cur_curdata for this paper-datatype if it has a value
      if ( $curData{$datatype}{$joinkey}{curator} ) { $thisCurator = $curData{$datatype}{$joinkey}{curator}; }
      my $curatorSelectCurator = qq(<select name="select_curator_curator_$trCounter" size="1">\n<option value=""></option>\n);
      foreach my $curator_two (keys %curators) {        # display curators in alphabetical (tied hash) order, if IP matches existing ip record, select it
        if ($thisCurator eq $curator_two) { $curatorSelectCurator .= qq(<option value="$curator_two" selected="selected">$curators{$curator_two}</option>\n); }
          else {                            $curatorSelectCurator .= qq(<option value="$curator_two">$curators{$curator_two}</option>\n); } }
      $curatorSelectCurator .= qq(</select>);

      $curatorSelectCurator .= qq(<input type="hidden" name="joinkey_$trCounter"  value="$joinkey" >);  # these are required, arbitrarily added here
      $curatorSelectCurator .= qq(<input type="hidden" name="datatype_$trCounter" value="$datatype">);  # these are required, arbitrarily added here
      push @dataRow, $curatorSelectCurator;

      my $thisDonPosNeg = ''; if ( $curData{$datatype}{$joinkey}{donposneg} ) { $thisDonPosNeg = $curData{$datatype}{$joinkey}{donposneg}; }
      my $curatorSelectDonposneg = qq(<select name="select_curator_donposneg_$trCounter">);
      foreach my $donposneg (keys %donPosNegOptions) {        # display curators in alphabetical (tied hash) order, if IP matches existing ip record, select it
        if ($thisDonPosNeg eq $donposneg) { $curatorSelectDonposneg .= qq(<option value="$donposneg" selected="selected">$donPosNegOptions{$donposneg}</option>\n); }
          else {                            $curatorSelectDonposneg .= qq(<option value="$donposneg"                    >$donPosNegOptions{$donposneg}</option>\n); } }
      $curatorSelectDonposneg .= qq(</select>);
      push @dataRow, $curatorSelectDonposneg;

      my $thisSelComment = ''; if ( $curData{$datatype}{$joinkey}{selcomment} ) { $thisSelComment = $curData{$datatype}{$joinkey}{selcomment}; }
      my $curatorSelectComment = qq(<select name="select_curator_comment_$trCounter">);
      $curatorSelectComment .= qq(<option value=""             ></option>\n);
      foreach my $comment (keys %premadeComments) {
        if ($thisSelComment eq $comment) { $curatorSelectComment .= qq(<option value="$comment" selected="selected">$premadeComments{$comment}</option>\n); }
          else {                           $curatorSelectComment .= qq(<option value="$comment"                    >$premadeComments{$comment}</option>\n); } }
      $curatorSelectComment .= qq(</select>);
      push @dataRow, $curatorSelectComment;

      my $txtcomment = ''; if ( $curData{$datatype}{$joinkey}{txtcomment} ) { $txtcomment = $curData{$datatype}{$joinkey}{txtcomment}; }
      my $shortTxtComment = $txtcomment;  unless ($shortTxtComment) { $shortTxtComment = ' '; }
      if ($txtcomment =~ m/^(.{20})/) { $shortTxtComment = $1; $shortTxtComment .= '...'; }
      my $curatorTextareaComment = qq(<div id="div_curator_comment_$trCounter" onclick="document.getElementById('div_curator_comment_$trCounter').style.display = 'none'; document.getElementById('textarea_curator_comment_$trCounter').style.display = ''; document.getElementById('textarea_curator_comment_$trCounter').focus();" >$shortTxtComment</div>\n);
      $curatorTextareaComment .= qq(<textarea rows="4" cols="80" id="textarea_curator_comment_$trCounter" name="textarea_curator_comment_$trCounter" style="display:none" onblur="document.getElementById('div_curator_comment_$trCounter').style.display = ''; document.getElementById('textarea_curator_comment_$trCounter').style.display = 'none'; var divValue = document.getElementById('textarea_curator_comment_$trCounter').value; if (divValue === '') { divValue = ' '; } document.getElementById('div_curator_comment_$trCounter').innerHTML = divValue; ">$txtcomment</textarea>\n);
#       $curatorTextareaComment .= qq(<textarea rows="4" cols="80" id="textarea_curator_comment_$trCounter" name="textarea_curator_comment_$trCounter" style="display:none" onblur="document.getElementById('div_curator_comment_$trCounter').style.display = ''; document.getElementById('textarea_curator_comment_$trCounter').style.display = 'none'; document.getElementById('div_curator_comment_$trCounter').innerHTML = document.getElementById('textarea_curator_comment_$trCounter').value.substring(0,20)">$txtcomment</textarea>\n);                 # to get the first 20 characters without adding ...
      push @dataRow, $curatorTextareaComment;

      $paperPosNegOkay{$joinkey}++;                             # all papers always okay for pos/neg since we no longer have pos/neg filtering  2012 11 08

      my $trData = join"</td>$tdDot", @dataRow;
      push @{ $trs{$joinkey} }, qq(${tdDot}$trData</td></tr>\n);
    } # foreach my $datatype (sort keys %{ $allPaperData{$joinkey} })
  } # foreach my $joinkey (sort keys %allPaperData)

The following code will print the rows of the table, displaying the requested information for each paper and paper-datatype pair. The code collects all relevant, valid papers and then calculates the number of pages that the results will be distributed across. The number of pages is calculated by dividing the total number of papers resulting from the query and dividing by the number of papers per page requested, and rounding up to an integer value. A drop-down menu is then generated and displayed, providing the curator with a means to access the paper results not available from the current page. A "Get Results" button is displayed which allows the curator to request a new page of results once a page has been selected from the page number drop-down menu. The form displays the total number of papers in the query result. The HTML table is then printed, adding column headers. Columns and their respective headers for cur_curdata (paper ID, curator, validation status, premade comment, and free-text comment) are always displayed, whereas all other columns and headers are optional. Cell borders are displayed with dotted lines.

To determine which papers to display on a page, the code determines what page number (n) is currently to be viewed and skips the first (n-1)*(papers per page) papers. The following paper and subsequent papers, up to the number requested per page, are then displayed. The code is written so that for each paper, the paper ID, PMID, journal, and PDF link are all only displayed once per paper, regardless of how many datatypes are being viewed. A "Submit New Results" button is then printed at the bottom of the complete table and the form is closed.

  print qq(<input type="hidden" name="trCounter" value="$trCounter">);

  my $joinkeysAmount = scalar(keys %paperPosNegOkay);
  my $pagesAmount = ceil($joinkeysAmount / $papersPerPage);
  print qq(Page number <select name="select_page">);
  for my $i (1 .. $pagesAmount) {
    if ($i == $pageSelected) { print qq(<option selected="selected">$i</option>\n); }
      else { print qq(<option>$i</option>\n); }
  } # for my $i (1 .. $pagesAmount)
  print qq(</select>);
  print qq(<input type="submit" name="action" value="Get Results">\n);
  print qq(amount of papers $joinkeysAmount<br/>\n);
  print qq(<br />\n);

  print qq(<table border="1">\n);
  push @headerRow, "datatype";
  if ($displaySvm)    { push @headerRow, "SVM Prediction"; }
  if ($displayStr)    { push @headerRow, "String Match"; }
  if ($displayCfp)    { push @headerRow, "cfp value"; }
  if ($displayAfp)    { push @headerRow, "afp value"; }
  if ($displayOa)     { push @headerRow, "oa value";  }
  push @headerRow, "curator"; push @headerRow, "new result"; push @headerRow, "select comment"; push @headerRow, "textarea comment";
  my $headerRow = join"</th>$thDot", @headerRow;
  $headerRow = qq(<tr>$thDot) . $headerRow . qq(</th></tr>);
  print qq($headerRow\n);

  my $papCount = 0;
  my $papCountToSkip = 0; my $papToSkip = ($pageSelected - 1 ) * $papersPerPage;
  foreach my $joinkey (sort keys %paperPosNegOkay) {                    # from all papers that have good positve-negative values, show all TRs
    $papCountToSkip++; next if ($papCountToSkip <= $papToSkip);         # skip entries until at the proper page
    $papCount++;
    last if ($papCount > $papersPerPage);
    my $trsInPaperAmount = scalar @{ $trs{$joinkey} };                  # amount of rows for a joinkey, make that the rowspan
    my $firstTr = shift @{ $trs{$joinkey} };                            # the first table row needs the paper info and rowspan
    my $tdMultiRow = $tdDot; $tdMultiRow =~ s/>$/ rowspan="$trsInPaperAmount">/;        # add the rowspan to the td style
    my $paperInfoTds = join"</td>$tdMultiRow", @{ $paperInfo{$joinkey} };               # make paper info tds from %paperInfo
    print qq(<tr>${tdMultiRow}$paperInfoTds</td>$firstTr\n);            # print the first row which has paper info
    foreach my $tr (@{ $trs{$joinkey} }) { print qq(<tr>$tr\n); } }     # print other table rows without paper info
  print qq(</table>\n);

  print qq(<input type="submit" name="action" value="Submit New Results"><br/>\n);

  &printFormClose();
} # sub getResults

Detailed Results of Papers Page: Processing Input (the submitNewResults Subroutine)

When a curator clicks on the "Submit New Results" button at the bottom of the Detailed Results of Papers Page, the submitNewResults subroutine (below) is run. First, the subroutine opens the form and prints the hidden curator, capturing the curator currently logged in. The code then looks at all paper-datatype pair data loaded by the getResults subroutine which generated the data to display on the Detailed Results of Papers Page, skipping over papers that do not have a "new result" (validation status) entry. For papers that have a "new result" entry, if there is a curator already listed in the curator field, that curator is kept as the curator for the given paper-datatype pair. If no curator is present in the field at the time of submission, the curator logged in is entered as the curator for the new data. Alternatively, if a curator has been manually selected from the curator drop-down menu, this selected curator is entered. The data from each row of the form with a "new result" entry is then compared to its respective data in Postgres. If the data is different it is prepared for display in the New Results Summary Page or the Overwrite Confirmation Page as described in the Add Results Page and the Add Results Page: Loading Page and Processing Input sections. Once complete, the form is closed.

sub submitNewResults {
  &printFormOpen();
  &printHiddenCurator();
  ($oop, my $trAmount) = &getHtmlVar($query, "trCounter");
  my %papersToAdd;
  my %curatorData;
  for my $i (1 .. $trAmount) {
    ($oop, my $curatorDonposneg) = &getHtmlVar($query, "select_curator_donposneg_$i");
    next unless $curatorDonposneg;                      # skip entries without a curator result for done / positive / negative
    ($oop, my $dropdownCurator)   = &getHtmlVar($query, "select_curator_curator_$i");
    my $activeCurator = $curator; if ($dropdownCurator) { $activeCurator = $dropdownCurator; }  # if a curator was chosen use that, otherwise use logged in curator
    ($oop, my $curatorSelComment) = &getHtmlVar($query, "select_curator_comment_$i");
    ($oop, my $curatorTxtComment) = &getHtmlVar($query, "textarea_curator_comment_$i");
    ($oop, my $joinkey)           = &getHtmlVar($query, "joinkey_$i");
    ($oop, my $datatype)          = &getHtmlVar($query, "datatype_$i");

    $papersToAdd{$datatype}{$joinkey}++;
    $curatorData{$joinkey}{$datatype}{curator}    = $activeCurator;
    $curatorData{$joinkey}{$datatype}{donposneg}  = $curatorDonposneg;
    $curatorData{$joinkey}{$datatype}{selcomment} = $curatorSelComment;
    $curatorData{$joinkey}{$datatype}{txtcomment} = $curatorTxtComment;
  } # for my $i (1 .. $trAmount)
  my %pgData;
  foreach my $datatype (sort keys %papersToAdd) {
    my $joinkeys = join"','", sort keys %{ $papersToAdd{$datatype} };
    my ($pgDatatypeDataRef) = &getPgDataForJoinkeys($joinkeys, $datatype);
    my %pgDatatypeData = %$pgDatatypeDataRef;
    foreach my $joinkey (keys %pgDatatypeData) {
      foreach my $datatype (keys %{ $pgDatatypeData{$joinkey} }) {
          foreach my $valuetype (keys %{ $pgDatatypeData{$joinkey}{$datatype} }) {
            $pgData{$joinkey}{$datatype}{$valuetype} = $pgDatatypeData{$joinkey}{$datatype}{$valuetype}; } } } }

  my @data; my @duplicateData;
  foreach my $joinkey (sort keys %curatorData) {
    foreach my $datatype (keys %{ $curatorData{$joinkey} }) {
        my $thisCurator  = $curatorData{$joinkey}{$datatype}{curator};
        my $donposneg    = $curatorData{$joinkey}{$datatype}{donposneg};
        my $selcomment   = $curatorData{$joinkey}{$datatype}{selcomment};
        my $txtcomment   = $curatorData{$joinkey}{$datatype}{txtcomment};
        my @line;
        push @line, $joinkey;
        push @line, $datatype;
        push @line, $thisCurator;
        push @line, $donposneg;
        push @line, $selcomment;
        push @line, $txtcomment;
        if ($pgData{$joinkey}{$datatype}) { push @duplicateData, \@line; }
          else { push @data, \@line; }
  } }
  &processResultDataDuplicateData(\@data, \@duplicateData, \%pgData);
  &printFormClose();
} # sub submitNewResults

Printing Curation Statistics Table

The beginning lines (and some later lines) of the printCurationStatisticsTable subroutine provide code to display the loading times of the Curation Statistics table as a whole, and the loading/processing times of each portion of the code. The lines are ignored when the variable $showTimes is set to zero. By default, all papers and datatypes are loaded for performing calculations and display. If only some flagging methods or datatypes are selected from the Curation Statistics Options Page, only papers flagged by the selected methods will load and only numbers for the selected datatypes will be displayed.

Row header columns are set to 600 pixels in width. Columns for individual datatypes are set to 120 pixels in width. If more than 6 datatypes are selected for viewing (via the Curation Statistics Options Page; ALL datatypes are selected by default), the row header column will appear at the right hand side of the table, in addition to the left hand side (default). The overall table width is calculated accordingly. Curatable papers and curated papers are populated into the table. Flagging methods are then loaded. ALL flagging methods (SVM, STR, AFP, CFP) are loaded by default, but specific flagging methods may be selected via the Curation Statistics Options Page. Column headers for each datatype (requested from the Curation Statistics Options Page or ALL datatypes if the main Curation Statistics Page) are then printed. The total number of curatable papers is printed once (for the entire table) followed by the number of objects curated (per datatype) and the average number of objects curated per paper (per datatype). Note that for the "rnai" datatype, curation statistics from 8 large scale papers have been manually added to the code as that data does not exist in the RNAi OA. 2084 objects coming from Chronograms have been manually added to the code for otherexpr as that data does not exist in the expression OA but only in Citace Minus. 19052 objects coming from expression images from Itai Yanai's study have been manually added to the code for picture as that data does not exist in the picture OA but only in Citace Minus.

Next are stats for all curated papers, then all validated papers, "Any" flagged papers and "Intersection" flagged papers. The statistics are calculated and then displayed for each of these sections, as determined by any options selected (if applicable).

sub printCurationStatisticsTable {
  my ($showTimes, $startprintCurationStatisticsTable, $start, $end, $diff) = (0, '', '', '', '');
  if ($showTimes) { $startprintCurationStatisticsTable = time; $start = $startprintCurationStatisticsTable; }

  $chosenPapers{all}++;
  my @datatypesToShow;

  &populateStatisticsHashToLabel();

  ($oop, my $all_datatypes_checkbox) = &getHtmlVar($query, "checkbox_all_datatypes");
  unless ($all_datatypes_checkbox) { $all_datatypes_checkbox = ''; }
  foreach my $datatype (sort keys %datatypes) {         # don't tie %datatypes
    ($oop, my $chosen) = &getHtmlVar($query, "checkbox_$datatype");
    if ($all_datatypes_checkbox eq 'all') { $chosen = $datatype; }      # if all datatypes checkbox was selected, set that datatype's chosen to that datatype
    if ($chosen) { $chosenDatatypes{$chosen}++; push @datatypesToShow, $datatype; }
  } # foreach my $datatype (sort %datatypes)

  my $datatypesToShowAmount = scalar @datatypesToShow;
  my $rowNameTdWidth = '600'; my $datatypeTdWidth = '120';
  my $labelRightFlag = 0; if ($datatypesToShowAmount > 6) { $labelRightFlag++; }
  my $tableWidth = $rowNameTdWidth + $datatypesToShowAmount * $datatypeTdWidth;
  if ($labelRightFlag) { $tableWidth = 2*$rowNameTdWidth + $datatypesToShowAmount * $datatypeTdWidth; }
  print qq(<table width="$tableWidth" class="bordered" border="1">\n);

  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "beforePopulateCuratablePapers   $diff<br>"; }
  &populateCuratablePapers();
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "populateCuratablePapers   $diff<br>"; }
  &populateCuratedPapers();
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "populateCuratedPapers   $diff<br>"; }

  my @flaggingMethods;                                          # when calculating any or all methods, only want papers for these flagging methods
  ($oop, my $displayAll) = &getHtmlVar($query, "checkbox_all_flagging_methods");
  ($oop, my $displayCfp) = &getHtmlVar($query, "checkbox_cfp");
  if ( ($displayAll) || ($displayCfp) ) { &populateCfpData();      push @flaggingMethods, 'checkbox_cfp'; }
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "populateCfpData $diff<br>"; }
  ($oop, my $displayAfp) = &getHtmlVar($query, "checkbox_afp");
  if ( ($displayAll) || ($displayAfp) ) { &populateAfpData();      push @flaggingMethods, 'checkbox_afp'; }
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "populateAfpData $diff<br>"; }
  ($oop, my $displayStr) = &getHtmlVar($query, "checkbox_str");
  if ($displayStr) { &populateStrData(); push @flaggingMethods, 'checkbox_str'; }
  ($oop, my $displaySvm) = &getHtmlVar($query, "checkbox_svm");
  if ( ($displayAll) || ($displaySvm) ) { &populateSvmData(); push @flaggingMethods, 'checkbox_svm'; }
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "populateSvmData   $diff<br>"; }
  my $flaggingMethods = join"=on&", @flaggingMethods; $flaggingMethods .= '=on';

  &printCurationStatisticsDatatypes(                \@datatypesToShow, $rowNameTdWidth, $datatypeTdWidth, $labelRightFlag);
  &printCurationStatisticsPapersCuratable(          \@datatypesToShow, $labelRightFlag);
  &printCurationStatisticsObjectsCurated(           \@datatypesToShow, $labelRightFlag);
  &printCurationStatisticsObjectsPerPaperCurated(   \@datatypesToShow, $labelRightFlag);

  $curStats{'dividerallval'}{'allSame'}{'countPap'} = 'blank';
  tie %{ $curStats{'allcur'} }, "Tie::IxHash";                  # make all section appear in this order by tying it
  tie %{ $curStats{'allval'} }, "Tie::IxHash";                  # make all section appear in this order by tying it
  $curStats{'dividerany'}{'allSame'}{'countPap'} = 'blank';
#   tie %{ $curStats{'any'} }, "Tie::IxHash";                   # not needed, 'any' only has 'pos'
  tie %{ $curStats{'any'}{'pos'} }, "Tie::IxHash";              # make any section appear in this order by tying it, though it will get populated last
  $curStats{'dividerint'}{'allSame'}{'countPap'} = 'blank';
  tie %{ $curStats{'int'}{'pos'} }, "Tie::IxHash";              # make any section appear in this order by tying it, though it will get populated last

  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "printCurationStatistics Datatypes / Objects   $diff<br>"; }

  &getCurationStatisticsAllCurated(         \@datatypesToShow );
  &getCurationStatisticsAllVal(             \@datatypesToShow );
  &getCurationStatisticsAllValPos(          \@datatypesToShow );
  &getCurationStatisticsAllValNeg(          \@datatypesToShow );
  &getCurationStatisticsAllValConf(         \@datatypesToShow );

  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "getCurationtStatisticsAll   $diff<br>"; }
  if ( ($displayAll) || ($displaySvm) ) {
    &getCurationStatisticsSvmNd(            \@datatypesToShow );
    &getCurationStatisticsSvm(              \@datatypesToShow ); }
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "getStatsSvm   $diff<br>"; }

  if ( ($displayAll) || ($displayStr) ) {
    &getCurationStatisticsStrFlagged(       \@datatypesToShow );
    &getCurationStatisticsStrPos(           \@datatypesToShow );
    &getCurationStatisticsStrNeg(           \@datatypesToShow ); }
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "getStatsStr   $diff<br>"; }

  if ( ($displayAll) || ($displayAfp) ) {
    &getCurationStatisticsAfpEmailed(       \@datatypesToShow );
    &getCurationStatisticsAfpFlagged(       \@datatypesToShow );
    &getCurationStatisticsAfpPos(           \@datatypesToShow );
    &getCurationStatisticsAfpNeg(           \@datatypesToShow ); }
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "getStatsAfp   $diff<br>"; }

  if ( ($displayAll) || ($displayCfp) ) {
    &getCurationStatisticsCfpFlagged(       \@datatypesToShow );
    &getCurationStatisticsCfpPos(           \@datatypesToShow );
    &getCurationStatisticsCfpNeg(           \@datatypesToShow ); }
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "getStatsCfp   $diff<br>"; }

  &getCurationStatisticsAny(                \@datatypesToShow, \@flaggingMethods );
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "getStatsAny   $diff<br>"; }

  my @labelKeys;                                        # labelKeys will be created here
  my $depth = 0;                                        # recursion depth into hash
  &recurseCurStats(\%curStats, \@labelKeys, $depth, \@datatypesToShow, $flaggingMethods, $labelRightFlag );
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "recurseCurStats   $diff<br>"; }

  &printCurationStatisticsDatatypes(                \@datatypesToShow, $rowNameTdWidth, $datatypeTdWidth, $labelRightFlag);
  print "</table>\n";
  if ($showTimes) { $end = time; $diff = $end - $startprintCurationStatisticsTable; print "printCurationStatisticsTable $diff<br>"; }
} # sub printCurationStatisticsTable

Premade Comments

In the Detailed Results of Papers page, curators have the option to select a comment from a drop down list of comments to apply to this paper in the context of the relevant datatype.

In the code, the comments are stored in a hash table called %premadeComments. The keys (stored in postgres) of these comments are only numbers, so the descriptions/titles can change or be updated and still apply retroactively.

Code:

sub populatePremadeComments {
  $premadeComments{"1"} = "SVM Positive, Curation Negative";
  $premadeComments{"2"} = "C. elegans as heterologous expression system";
  $premadeComments{"3"} = "pre-made comment #3";}

So, as of now:

| Key |            Comment                                    |
|  1  | "SVM Positive, Curation Negative"                     |
|  2  | "C. elegans as heterologous expression system"        |
|  3  | "pre-made comment #3"                                 |

Hence, if a completely new comment is desired, a new key will need to be made and there after associated with that new comment. Also, old keys should never be recycled and documentation describing what each key refers to should be maintained in this Wiki.

New Result

Each paper-datatype pair can be assigned a "New Result" indicating its status as curated (or not) or validated (or not), and if validated, positive or negative for the particular paper-datatype pair. These results can be entered via the Add Results Page or directly in the Detailed Results of Papers page via the "New Results" column. The code is below:

Code:

sub populateDonPosNegOptions {
  $donPosNegOptions{""}             = "";
  $donPosNegOptions{"curated"}      = "curated and positive";
  $donPosNegOptions{"positive"}     = "validated positive";
  $donPosNegOptions{"negative"}     = "validated negative";
  $donPosNegOptions{"notvalidated"} = "not validated";}

where "curated", "positive", "negative", and "notvalidated" are the keys (for the %donPosNegOptions hash table in the form code) that will be stored in postgres and the corresponding values (e.g. "curated and positive") are what will be displayed on the form.

Note that "" and "not validated" represent no data for that paper-datatype pair, but "not validated" is present as an option to overwrite accidental validations (it is impossible to go back to a blank "" field via the form).

Datatypes

The form determines which datatypes exist via a 'populateDatatypes' subroutine in the form code. As of 12-5-2012, the form first collects all datatypes used in SVM from the 'cur_svmdata' postgres table (which, as of 12-5-2012, all also are identically named in the Author First Pass (AFP) and Curator First Pass (CFP) tables) and then supplements with other datatypes not in SVM but in AFP and CFP (as of 12-5-2012, all anatomy curation related datatypes) plus one additional datatype ("geneticablation") not in SVM, AFP, or CFP.

Here is the code:

sub populateDatatypes {
  $result = $dbh->prepare( "SELECT DISTINCT(cur_datatype) FROM cur_svmdata " );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) { $datatypesAfpCfp{$row[0]} = $row[0]; }
  $datatypesAfpCfp{'chemicals'} = 'chemicals';      # added for Karen 2013 10 02
  $datatypesAfpCfp{'blastomere'}    = 'cellfunc';
  $datatypesAfpCfp{'exprmosaic'}    = 'siteaction';
  $datatypesAfpCfp{'geneticmosaic'} = 'mosaic';
  $datatypesAfpCfp{'laserablation'} = 'ablationdata';
  foreach my $datatype (keys %datatypesAfpCfp) { $datatypes{$datatype}++; }
  $datatypes{'geneticablation'}++;
  $datatypes{'picture'}++;          # for Daniela's pictures
  $result = $dbh->prepare( "SELECT DISTINCT(cur_datatype) FROM cur_strdata" );  # from string search data
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) { $datatypes{$row[0]} = $row[0]; }
} # sub populateDatatypes

As for the datatypes currently (12-5-2012) NOT in SVM but IN AFP and CFP, the datatype name is different between the Curation Status form and the AFP and CFP forms. So, the datatypes named "cellfunc", "siteaction", "mosaic", and "ablationdata" in the AFP and CFP tables are respectively named "blastomere", "exprmosaic", "geneticmosaic", "laserablation" in the Curation Status form.

The IMPORTANT thing here is: if, at some point, the datatypes are changed (added, renamed, etc.), and the code is not updated in kind, the form will likely break. Curators should tell Juancarlos/Chris/Daniela to update the code.

new datatypes should be accounted in this code :

• - no svm, no str/afp/cfp : add to %datatypes hash like 'geneticablation'.
• - no svm, no str, yes afp/cfp : add to %datatypesAfpCfp + %datatypes hashes like 'blastomere'
• - yes svm, yes afp/cfp, no str : add to code to populate cur_svmdata, which will populate in the SELECT query
• - yes svm, no str/afp/cfp : add to code to populate cur_svmdata, which will populate in the SELECT query, but also subsequently delete from %datatypesAfpCfp (to prevent a postgres query to a non-existing table which will crash the form)

Read str results from cur_strdata into %datatypes hash.

On February 3rd 2015 we have added catalyticactivity (catalyticact) datatype as it was added in the SVM pipeline. It has SVM results, no afp / cfp / string / oa_data / form_data, and any positives only come through data entered through the curation status form (DR)

Creating PDF links to papers

In the Detailed Results of Papers page, each paper ID is linked to its corresponding PDF document using the code below:

Code:

sub populatePdf {
  $result = $dbh->prepare( "SELECT * FROM pap_electronic_path WHERE pap_electronic_path IS NOT NULL");
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  my %temp;
  while (my @row = $result->fetchrow) {
    my ($data, $isPdf) = &makePdfLinkFromPath($row[1]);
    $temp{$row[0]}{$isPdf}{$data}++; }
  foreach my $joinkey (sort keys %temp) {
    my @pdfs;
    foreach my $isPdf (reverse sort keys %{ $temp{$joinkey} }) {
      foreach my $pdfLink (sort keys %{ $temp{$joinkey}{$isPdf} }) {
        push @pdfs, $pdfLink; } }
    my ($pdfs) = join"<br/>", @pdfs;
    $pdf{$joinkey} = $pdfs;
  } # foreach my $joinkey (sort keys %temp)
} # sub populatePdf

sub makePdfLinkFromPath {
  my ($path) = shift;
  my ($pdf) = $path =~ m/\/([^\/]*)$/;
  my $isPdf = 0; if ($pdf =~ m/\.pdf$/) { $isPdf++; }           # kimberly wants .pdf files on top, so need to flag to sort
  my $link = 'http://tazendra.caltech.edu/~acedb/daniel/' . $pdf;
  my $data = "<a href=\"$link\" target=\"new\">$pdf</a>"; return ($data, $isPdf); }

Note the table name ("pap_electronic_path"), the URL path ("http://tazendra.caltech.edu/~acedb/daniel/"), and (because of the code 'target=\"new\"') that the link will open a new window or tab. Also note that opening another link on the original page (e.g. Detailed Results of Papers page) will open that link in that same new window/tab, clearing out what you had opened previously.

Creating hyperlinks to PubMed paper pages

In the Detailed Results of Papers page each PubMed ID is linked to its corresponding PubMed webpage using the code below:

Code:

sub populatePmid {
  $result = $dbh->prepare( "SELECT * FROM pap_identifier WHERE pap_identifier ~ 'pmid'" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  my %temp;
  while (my @row = $result->fetchrow) { if ($row[0]) {
    my ($data) = &makeNcbiLinkFromPmid($row[1]);
    $temp{$row[0]}{$data}++; } }
  foreach my $joinkey (sort keys %temp) {
    my ($pmids) = join"<br/>", keys %{ $temp{$joinkey} };
    $pmid{$joinkey} = $pmids;
  } # foreach my $joinkey (sort keys %temp)
} # sub populatePmid

sub makeNcbiLinkFromPmid {
  my $pmid = shift;
  my ($id) = $pmid =~ m/(\d+)/;
  my $link = 'http://www.ncbi.nlm.nih.gov/pubmed/' . $id;
  my $data = "<a href=\"$link\" target=\"new\">$pmid</a>"; return $data; }

Note the table name ("pap_identifier"), the table specifier ("WHERE pap_identifier ~ 'pmid'"), the URL path ("http://www.ncbi.nlm.nih.gov/pubmed/"), and (because of the code 'target=\"new\"') that the link will open a new window or tab. Also note that opening another link on the original page (e.g. Detailed Results of Papers page) will open that link in that same new window/tab, clearing out what you had opened previously.

Populating the Journal Names

Journal names for each paper are populated via the following code:

sub populateJournal {
  $result = $dbh->prepare( "SELECT * FROM pap_journal WHERE pap_journal IS NOT NULL" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) { if ($row[0]) { $journal{$row[0]} = $row[1]; } }
} # sub populateJournal

Note the table "pap_journal".

Loading Data into the Form

On the Curation Statistics Options Page, the Specific Paper Page, or the Prepopulated Specific Papers Page, curators have the option to specify what flagging methods (SVM, STR, AFP, and/or CFP), curation sources (Ontology Annotator or cur_curdata [which is the data generated from this form]), and/or datatypes (e.g. geneint, rnai) they would like to view.

There are separate hashes for storing the different types of data, all of which have a key of datatype, subkey paperID, sub-subkeys of other things depending on the hash (see individual subsections below).

There is an option to select specific datatype, in which case only the data for those datatypes is loaded. Similarly if only some paperIDs have been selected, only those paperIDs are loaded.

Loading curatable papers

Only papers that have a 'valid' pap_status value and a 'primary' pap_primary_data value are considered curatable. These are stored in the %curatablePapers hash. ( paperID => status )

sub populateCuratablePapers {
  my $query = "SELECT * FROM pap_status WHERE pap_status = 'valid' AND joinkey IN (SELECT joinkey FROM pap_primary_data WHERE pap_primary_data = 'primary')";
  $result = $dbh->prepare( $query );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) { $curatablePapers{$row[0]} = $row[1]; }
} # sub populateCuratablePapers

Loading afp_ data

Populate %afpEmailed, %afpData, %afpFlagged, %afpPos, %afpNeg.

for each of the chosen datatypes, if they are allowed in %datatypeAfpCfp, query the corresponding afp_ postgres table, and if it's a curatable paper store the value in the %afpData hash (datatype, paper ID => AFP result).

Query afp_email and if it's a curatable paper store in %afpEmailed hash ( paperID => 1 ) for afp emailed statistics.

Query afp_lasttouched to see if a paper has been flagged for afp. Skip if it's not a curatable paper. For all %chosenDatatypes store in %afpFlagged ( datatype, paperID => 1 )

For each of the %afpFlagged datatypes that have been chosen (%chosenDatatypes), if there is an %afpData value, store in %afpPos hash ( positive flag for afp ), otherwise store in %afpNeg hash (negative flag for afp ) ( datatype, paperID => 1 )

sub populateAfpData {
  foreach my $datatype (sort keys %chosenDatatypes) {
    next unless $datatypesAfpCfp{$datatype};
    my $pgtable_datatype = $datatypesAfpCfp{$datatype};
    $result = $dbh->prepare( "SELECT * FROM afp_$pgtable_datatype" );
    $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
    while (my @row = $result->fetchrow) {
      next unless ($curatablePapers{$row[0]});
      $afpData{$datatype}{$row[0]} = $row[1]; }
  } # foreach my $datatype (sort keys %chosenDatatypes)

  $result = $dbh->prepare( "SELECT * FROM afp_email" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) {
    next unless ($curatablePapers{$row[0]});
    $afpEmailed{$row[0]}++; }
  $result = $dbh->prepare( "SELECT * FROM afp_lasttouched" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) {
    next unless ($curatablePapers{$row[0]});
    foreach my $datatype (sort keys %chosenDatatypes) {
      $afpFlagged{$datatype}{$row[0]}++; } }
  foreach my $datatype (sort keys %chosenDatatypes) {
    foreach my $joinkey (sort keys %{ $afpFlagged{$datatype} }) {
      if ($afpData{$datatype}{$joinkey}) { $afpPos{$datatype}{$joinkey}++; }
        else { $afpNeg{$datatype}{$joinkey}++; } } }
} # sub populateAfpData

Loading cfp_ data

Populate %cfpData, %cfpFlagged, %cfpPos, %cfpNeg.

for each of the chosen datatypes, if they are allowed in %datatypeAfpCfp, query the corresponding cfp_ postgres table, and if it's a curatable paper store the value in the %cfpData hash (datatype, paper ID => CFP result).

Query cfp_curator to see if a paper has been flagged for cfp. Skip if it's not a curatable paper. For all %chosenDatatypes store in %cfpFlagged ( datatype, paperID => 1 )

For each of the %cfpFlagged datatypes that have been chosen (%chosenDatatypes), if there is an %cfpData value, store in %cfpPos hash ( positive flag for cfp ), otherwise store in %cfpNeg hash (negative flag for cfp ) ( datatype, paperID => 1 )

sub populateCfpData {
  foreach my $datatype (sort keys %chosenDatatypes) {
    next unless $datatypesAfpCfp{$datatype};
    my $pgtable_datatype = $datatypesAfpCfp{$datatype};
    $result = $dbh->prepare( "SELECT * FROM cfp_$pgtable_datatype" );
    $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
    while (my @row = $result->fetchrow) {
      next unless ($curatablePapers{$row[0]});
      $cfpData{$datatype}{$row[0]} = $row[1]; }
  } # foreach my $datatype (sort keys %chosenDatatypes)

  $result = $dbh->prepare( "SELECT * FROM cfp_curator" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) {
    next unless ($curatablePapers{$row[0]});
    foreach my $datatype (sort keys %chosenDatatypes) {
      $cfpFlagged{$datatype}{$row[0]}++; } }
  foreach my $datatype (sort keys %chosenDatatypes) {
    foreach my $joinkey (sort keys %{ $cfpFlagged{$datatype} }) {
      if ($cfpData{$datatype}{$joinkey}) { $cfpPos{$datatype}{$joinkey}++; }
        else { $cfpNeg{$datatype}{$joinkey}++; } } }
} # sub populateCfpData

Loading str data

Populate %strData, %strFlagged, %strPos, %strNeg.

For each of the chosen datatypes, query the cur_strdata table where cur_datatype is that datatype. The string result is the 4th column, the paper ID is the first column. skip papers that are not %curatablePapers. store in %strData ( datatype, paper => str_result ). cur_strdata only has a single result for a given paper-datatype pair, replaced as a whole each time the cronjob runs.

All curatable papers are considered flagged for STR. It's positive if it's in cur_strdata, and negative if it's not.

  $result = $dbh->prepare( "SELECT * FROM cur_strdata" );           # only single value ever stored per paper
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) {
    my $joinkey = $row[0]; my $datatype = $row[1]; my $strdata = $row[3];
    next unless ($curatablePapers{$row[0]});
    $strData{$datatype}{$joinkey} = $strdata; }
  foreach my $datatype (sort keys %strData) {
    foreach my $joinkey (sort keys %curatablePapers) {
      $strFlagged{$datatype}{$joinkey}++;
      if ($strData{$datatype}{$joinkey}) { $strPos{$datatype}{$joinkey}++; }
        else { $strNeg{$datatype}{$joinkey}++; } } }

Loading svm data

Populate %svmData hash.

For each of the chosen datatypes, query the cur_svmdata table where cur_datatype is that datatype, and sort by cur_date so that we always have the latest value for a given paper-datatype pair. The svm result is the 4th column, the paper ID is the first column. skip papers that are not %curatablePapers. store in %svmData ( datatype, paper => svm_result ). cur_svmdata could have multiple results for a given paper-datatype pair, we'll consider only the most recent result (by the directory name/date on Yuling's machine).

sub populateSvmData {
#     $result = $dbh->prepare( "SELECT * FROM cur_svmdata ORDER BY cur_datatype, cur_date" );   # always doing for all datatypes vs looping for chosen takes 4.66vs 2.74 secs
  foreach my $datatype (sort keys %chosenDatatypes) {
    $result = $dbh->prepare( "SELECT * FROM cur_svmdata WHERE cur_datatype = '$datatype' ORDER BY cur_date" );
      # table stores multiple dates for same paper-datatype in case we want to see multiple results later.  if it didn't and we didn't order it would take 2.05 vs 2.74 secs, so not worth changing the way we're storing data
    $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
    while (my @row = $result->fetchrow) {
      my $joinkey = $row[0]; my $svmdata = $row[3];
      next unless ($curatablePapers{$row[0]});
      $svmData{$datatype}{$joinkey} = $svmdata; } }
} # sub populateSvmData

Loading OA data

Populate %objsCurated and %oaData hashes.

Each datatype is stored in different tables and has to be queried separately. The queries are mostly the same.

  if ($chosenDatatypes{'newmutant'}) {
    $result = $dbh->prepare( "SELECT * FROM app_variation" );
    $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
    while (my @row = $result->fetchrow) { $objsCurated{'newmutant'}{$row[1]}++; }
    $result = $dbh->prepare( "SELECT * FROM app_paper" );
    $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
    while (my @row = $result->fetchrow) {
      my (@papers) = $row[1] =~ m/WBPaper(\d+)/g;
      foreach my $paper (@papers) {
        $oaData{'newmutant'}{$paper} = 'curated'; } } }

and similarly for other datatypes.

The example above is for the datatype 'newmutant'. If that datatype is a %chosenDatatypes, query app_variation and store in %objsCurated ( datatype, object => 1 ), then query app_paper matching for WBPaper IDs, and associating to %oaData ( datatype, paperID => 'curated' ).

For other datatypes :

• overexpr : objects from app_transgene ; %oaData from app_paper WHERE joinkey IN (SELECT joinkey FROM app_transgene WHERE app_transgene IS NOT NULL AND app_transgene != ), meaning papers where the postgresID has a corresponding transgene that exists in app_transgene.
• antibody : objects from abp_name ; %oaData from abp_paper
• seqfeature : objects from sqf_name ; %oaData from sqf_paper
• humandisease : objects from dis_wbgene ; %oaData from dis_paperdisrel and dis_paperexpmod
• otherexpr : objects from exp_name ; %oaData from exp_paper
• genereg : objects from grg_name; %oaData from grg_paper
• geneint : objects from int_name; %oaData from int_paper
• rnai : objects from rna_name; %oaData from rna_paper
• blastomere : objects from wbb_wbbtf WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Blastomere_isolation') ; %oaData from wbb_reference WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Blastomere_isolation')
• exprmosaic : objects from wbb_wbbtf WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Expression_mosaic') ; %oaData from wbb_reference WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Expression_mosaic')
• geneticablation : objects from wbb_wbbtf WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Genetic_ablation') ; %oaData from wbb_reference WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Genetic_ablation')
• geneticmosaic : objects from wbb_wbbtf WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Genetic_mosaic') ; %oaData from wbb_reference WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Genetic_mosaic')
• laserablation : objects from wbb_wbbtf WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Laser_ablation') ; %oaData from wbb_reference WHERE joinkey IN (SELECT joinkey FROM wbb_assay WHERE wbb_assay = 'Laser_ablation')
• chemicals :
  • do 5 postgres queries to find unique curated objects into %objsCurated{chemicals}{<chemical>}

- SELECT * FROM mop_name WHERE joinkey IN (SELECT joinkey FROM mop_paper WHERE mop_paper IS NOT NULL AND mop_paper != '')
- SELECT * FROM grg_moleculeregulator match for WBMol:\d+
- SELECT * FROM app_molecule match for WBMol:\d+
- SELECT * FROM pro_molecule match for WBMol:\d+
- SELECT * FROM rna_molecule match for WBMol:\d+

• • do 7 postgres queries to find unique curated papers and match for WBPaper\d+ into $oaData{'chemicals'}{<paper>} = 'curated' :

- SELECT * FROM mop_paper
- SELECT * FROM app_paper WHERE joinkey IN (SELECT joinkey FROM app_molecule WHERE app_molecule IS NOT NULL AND app_molecule != '')
- SELECT * FROM grg_paper WHERE joinkey IN (SELECT joinkey FROM grg_moleculeregulator WHERE grg_moleculeregulator IS NOT NULL AND grg_moleculeregulator != '')
- SELECT * FROM pro_paper WHERE joinkey IN (SELECT joinkey FROM pro_molecule WHERE pro_molecule IS NOT NULL AND pro_molecule != '')
- SELECT * FROM rna_paper WHERE joinkey IN (SELECT joinkey FROM rna_molecule WHERE rna_molecule IS NOT NULL AND rna_molecule != '')
- SELECT * FROM int_paper WHERE joinkey IN (SELECT joinkey FROM int_moleculeone WHERE int_moleculeone IS NOT NULL) OR joinkey IN (SELECT joinkey FROM int_moleculetwo WHERE int_moleculetwo IS NOT NULL) OR joinkey IN (SELECT joinkey FROM int_moleculenondir WHERE int_moleculenondir IS NOT NULL)

Loading cur_curdata

cur_curdata: this captures all data entered through this form, meaning paper ID, datatype, curator ID, validation status (e.g. "curated and positive"), pre-canned comment, and/or free text comment (and timestamp). Note: this table only stores data (and associated paper-datatype pairs) that has been manually entered through this form.

Code:

sub populateCurCurData {
  $result = $dbh->prepare( "SELECT * FROM cur_curdata ORDER BY cur_timestamp" );        # in case multiple values get in for a paper-datatype (shouldn't happen), keep the latest
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) {
    next unless ($chosenPapers{$row[0]} || $chosenPapers{all});
    next unless ($chosenDatatypes{$row[1]});
    $curData{$row[1]}{$row[0]}{curator}    = $row[2];
    $curData{$row[1]}{$row[0]}{donposneg}  = $row[3];
    $curData{$row[1]}{$row[0]}{selcomment} = $row[4];
    $curData{$row[1]}{$row[0]}{txtcomment} = $row[5];
    $curData{$row[1]}{$row[0]}{timestamp}  = $row[6]; }
} # sub populateCurCurData

When populating curator data from curation status, read the cur_curdata postgres table, skip datatypes that were not chosen, skip papers that were not chosen. Store data in the %curData hash, key is datatype, subkey is paperID, then valuekeys are curator, donposneg (curator result of curated, validatedPos, validatedNeg, notValidated), select comment, text comment, timestamp.

cur_curdata can only have one result for a specific paper-datatype pair, if a new result is entered it will overwrite the previous result.

Loading cur_curdata --- Code changes for June 12, 2013

The code above was changed to accommodate the change in how we handle "not validated" flags. The code has one extra line:

    next if ( ($row[3] eq 'notvalidated') || ($row[3] eq '') );                                         # skip entries marked as notvalidated

The new code, in total, is:

sub populateCurCurData {
  $result = $dbh->prepare( "SELECT * FROM cur_curdata ORDER BY cur_timestamp" );        # in case multiple values get in for a paper-datatype (shouldn't happen), keep the latest
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) {
    next unless ($chosenPapers{$row[0]} || $chosenPapers{all});
    next unless ($chosenDatatypes{$row[1]});
    next if ( ($row[3] eq 'notvalidated') || ($row[3] eq '') );                                         # skip entries marked as notvalidated
    $curData{$row[1]}{$row[0]}{curator}    = $row[2];
    $curData{$row[1]}{$row[0]}{donposneg}  = $row[3];
    $curData{$row[1]}{$row[0]}{selcomment} = $row[4];
    $curData{$row[1]}{$row[0]}{txtcomment} = $row[5];
    $curData{$row[1]}{$row[0]}{timestamp}  = $row[6]; }
} # sub populateCurCurData

Loading cur_curdata --- Code Changes for May 12th, 2017

• Updates were made to the cur_curdata table to accommodate entry of parasite paper data
• A new column in cur_curdata was added that records for which group a data type was curated
  • The column is cur_site and the values are: caltech or parasite
  • A paper can be flagged for the same data type for each site; if flagged by more than one site, the form will create separate entries in a row in the table

Processing curated data

The following subroutine will process cur_curdata and oaData into %valCur %valPos %valNeg and into %conflict which has the paper-datatypes that have multiple values, which correspond to a datatype-paper pair's validated+curated, validated+positive, validated+negative.

If a paper has been curated for a datatype, the paper enters into the %valCur AND the %valPos hashes; if it has been validated positive but NOT curated it goes into %valPos ONLY; and if it has been validated negative it will go into %valNeg.

sub populateCuratedPapers {
  my ($showTimes, $start, $end, $diff) = (0, '', '', '');
  if ($showTimes) { $start = time; }
  &populateCurCurData();
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "IN populateCuratedPapers  populateCurCurData $diff<br>"; }
  &populateOa();                                                # $oaData{datatype}{joinkey} = 'positive';
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "IN populateCuratedPapers  populateOa $diff<br>"; }
  my %allCuratorValues;                 # $allCuratorValues{datatype}{joinkey} = 0 | 1+
  foreach my $datatype (sort keys %oaData) {
    foreach my $joinkey (sort keys %{ $oaData{$datatype} }) {
      $allCuratorValues{$joinkey}{$datatype}{curated}++; } }            # validated positive and curated
  foreach my $datatype (sort keys %curData) {
    foreach my $joinkey (sort keys %{ $curData{$datatype} }) {
      $allCuratorValues{$joinkey}{$datatype}{ $curData{$datatype}{$joinkey}{donposneg} }++; } }
  foreach my $joinkey (sort keys %allCuratorValues) {
     next unless ($curatablePapers{$joinkey});                              # skips non-primary papers
    foreach my $datatype (sort keys %{ $allCuratorValues{$joinkey} }) {
      my @values = keys %{ $allCuratorValues{$joinkey}{$datatype} };
      if (scalar @values > 1) { $conflict{$datatype}{$joinkey}++; }
        else {
          my $value = shift @values;
          $validated{$datatype}{$joinkey} = $value;
          if ($value eq 'curated') {       $valPos{$datatype}{$joinkey} = $value; $valCur{$datatype}{$joinkey} = $value; }
            elsif ($value eq 'positive') { $valPos{$datatype}{$joinkey} = $value; }
            elsif ($value eq 'negative') { $valNeg{$datatype}{$joinkey} = $value; }
  } } }
  if ($showTimes) { $end = time; $diff = $end - $start; $start = time; print "IN populateCuratedPapers  categorizing hash $diff<br>"; }
} # sub populateCuratedPapers

Processing curated data --- Code changes for June 12, 2013

The code in the section above was changed to accommodate a change in the way we recognize and handle paper conflicts. The following code:

      my @values = keys %{ $allCuratorValues{$joinkey}{$datatype} };
      if (scalar @values > 1) { $conflict{$datatype}{$joinkey}++; }
        else {
          my $value = shift @values;
          $validated{$datatype}{$joinkey} = $value;
          if ($value eq 'curated') {       $valPos{$datatype}{$joinkey} = $value; $valCur{$datatype}{$joinkey} = $value; }
            elsif ($value eq 'positive') { $valPos{$datatype}{$joinkey} = $value; }
            elsif ($value eq 'negative') { $valNeg{$datatype}{$joinkey} = $value; }

was changed to:

      my @values = keys %{ $allCuratorValues{$joinkey}{$datatype} };
      if (scalar @values < 2) {                 # only one value, categorize it
          my $value = shift @values;
          $validated{$datatype}{$joinkey} = $value;
          if ($value eq 'curated') {       $valPos{$datatype}{$joinkey} = $value; $valCur{$datatype}{$joinkey} = $value; }
            elsif ($value eq 'positive') { $valPos{$datatype}{$joinkey} = $value; }
            elsif ($value eq 'negative') { $valNeg{$datatype}{$joinkey} = $value; } }
        elsif (scalar @values == 2) {           # only two values, either ok or conflict
            if ( ($allCuratorValues{$joinkey}{$datatype}{'curated'}) && ($allCuratorValues{$joinkey}{$datatype}{'positive'}) ) {        # positive + curated not a conflict, for Chris 2013 06 12
                $valPos{$datatype}{$joinkey} = 'positive'; $valCur{$datatype}{$joinkey} = 'curated'; }
              else { $conflict{$datatype}{$joinkey}++; } }
        else { $conflict{$datatype}{$joinkey}++; }

Curation Statistics Calculations

The way that each value is calculated for Curation Statistics table is based on what papers (or, more specifically, paper IDs) populate each of a number of tables. The following hash tables capture validation status:

%valCur - All papers that have been curated for a given datatype

%valPos - All papers that have been validated positive for a given datatype, but not yet curated

%valNeg - All papers that have been validated negative for a given datatype

When determining, for a particular flagging method, the validation and curation statistics with respect to flagging status, these tables are compared to the table for flagging results to generate the numbers for the Curation Statistics table. So, for AFP Positives for example, the following logic is performed to determine the indicated values (list of papers), per datatype:

AFP positive (%afpPos)
AFP positive validated (%afpPosVal)                             : %afpPos AND (%valNeg OR %valPos)
AFP positive validated false positive (%afpPosFP)               : %afpPos AND %valNeg
AFP positive validated true positive (%afpPosTP)                : %afpPos AND %valPos
AFP positive validated true positive curated (%afpPosTpCur)     : %afpPos AND %valPos AND %valCur    <Note: the %valPOS is redundant>
AFP positive validated true positive not curated (%afpPosTpNC)  : %afpPos AND (%valPos NOT %valCur)
AFP positive not validated (%afpPosNV)                          : %afpPos NOT (%valNeg OR %valPos)
AFP positive not curated (%afpPosNC)                            : (%afpPos AND (%valPos NOT %valCur)) OR (%afpPos NOT (%valNeg OR %valPos))

which are determined by the following section of code:

sub getCurationStatisticsAfpPos {
  my ($datatypesToShow_ref) = @_;
  my @datatypesToShow = @$datatypesToShow_ref;
  my %afpPosNV; my %afpPosVal; my %afpPosFP; my %afpPosTP; my %afpPosTpCur; my %afpPosTpNC; my %afpPosNC;
        # positive and : not validated, validated, false positive, true positive, TP curated, TP not curated, not curated minus validated negative OR not validated + TP not curated
  foreach my $datatype (@datatypesToShow) {
    foreach my $joinkey (sort keys %{ $afpPos{$datatype} }) {
      if ($valPos{$datatype}{$joinkey}) {      $afpPosTP{$datatype}{$joinkey}++;     $afpPosVal{$datatype}{$joinkey}++;
          if ($valCur{$datatype}{$joinkey}) {  $afpPosTpCur{$datatype}{$joinkey}++; }
            else                            {   $afpPosTpNC{$datatype}{$joinkey}++;  $afpPosNC{$datatype}{$joinkey}++; } }
        elsif ($valNeg{$datatype}{$joinkey}) { $afpPosFP{$datatype}{$joinkey}++;     $afpPosVal{$datatype}{$joinkey}++; }
        else {                                 $afpPosNV{$datatype}{$joinkey}++;     $afpPosNC{$datatype}{$joinkey}++; } } }
  tie %{ $curStats{'afp'}{'pos'} }, "Tie::IxHash";
  foreach my $datatype (@datatypesToShow) {
    my $countAfpFlagged   = scalar keys %{ $afpFlagged{$datatype} };
    my $countAfpPos = scalar keys %{ $afpPos{$datatype} };
    my $ratio = 0;
    if ($countAfpFlagged > 0) { $ratio = $countAfpPos / $countAfpFlagged * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpPos{$datatype} }) {      $curStats{'afp'}{'pos'}{$datatype}{papers}{$joinkey}++;
                                                              $curStats{'any'}{'pos'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'pos'}{$datatype}{'countPap'}                      = scalar keys %{ $afpPos{$datatype} };
    $curStats{'afp'}{'pos'}{$datatype}{'ratio'}                         = $ratio;

    my $countAfpPosVal  = scalar keys %{ $afpPosVal{$datatype} };
    $ratio = 0;
    if ($countAfpPos > 0) { $ratio = $countAfpPosVal / $countAfpPos * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpPosVal{$datatype} }) {   $curStats{'afp'}{'pos'}{'val'}{$datatype}{papers}{$joinkey}++;
                                                              $curStats{'any'}{'pos'}{'val'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'pos'}{'val'}{$datatype}{'countPap'}               = scalar keys %{ $afpPosVal{$datatype} };
    $curStats{'afp'}{'pos'}{'val'}{$datatype}{'ratio'}                  = $ratio;

    my $countAfpPosTP  = scalar keys %{ $afpPosTP{$datatype} };
    $ratio = 0;
    if ($countAfpPosVal > 0) { $ratio = $countAfpPosTP / $countAfpPosVal * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpPosTP{$datatype} }) {    $curStats{'afp'}{'pos'}{'val'}{'tp'}{$datatype}{papers}{$joinkey}++;
                                                              $curStats{'any'}{'pos'}{'val'}{'tp'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'pos'}{'val'}{'tp'}{$datatype}{'countPap'}         = scalar keys %{ $afpPosTP{$datatype} };
    $curStats{'afp'}{'pos'}{'val'}{'tp'}{$datatype}{'ratio'}            = $ratio;

    my $countAfpPosTpCur  = scalar keys %{ $afpPosTpCur{$datatype} };
    $ratio = 0;
    if ($countAfpPosTP > 0) { $ratio = $countAfpPosTpCur / $countAfpPosTP * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpPosTpCur{$datatype} }) { $curStats{'afp'}{'pos'}{'val'}{'tp'}{'cur'}{$datatype}{papers}{$joinkey}++;
                                                              $curStats{'any'}{'pos'}{'val'}{'tp'}{'cur'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'pos'}{'val'}{'tp'}{'cur'}{$datatype}{'countPap'}  = scalar keys %{ $afpPosTpCur{$datatype} };
    $curStats{'afp'}{'pos'}{'val'}{'tp'}{'cur'}{$datatype}{'ratio'}     = $ratio;

    my $countAfpPosTpNC  = scalar keys %{ $afpPosTpNC{$datatype} };
    $ratio = 0;
    if ($countAfpPosTP > 0) { $ratio = $countAfpPosTpNC / $countAfpPosTP * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpPosTpNC{$datatype} }) {  $curStats{'afp'}{'pos'}{'val'}{'tp'}{'ncur'}{$datatype}{papers}{$joinkey}++;
                                                              $curStats{'any'}{'pos'}{'val'}{'tp'}{'ncur'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'pos'}{'val'}{'tp'}{'ncur'}{$datatype}{'countPap'} = scalar keys %{ $afpPosTpNC{$datatype} };
    $curStats{'afp'}{'pos'}{'val'}{'tp'}{'ncur'}{$datatype}{'ratio'}    = $ratio;

    my $countAfpPosFP  = scalar keys %{ $afpPosFP{$datatype} };
    $ratio = 0;
    if ($countAfpPosVal > 0) { $ratio = $countAfpPosFP / $countAfpPosVal * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpPosFP{$datatype} }) {    $curStats{'afp'}{'pos'}{'val'}{'fp'}{$datatype}{papers}{$joinkey}++;
                                                              $curStats{'any'}{'pos'}{'val'}{'fp'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'pos'}{'val'}{'fp'}{$datatype}{'countPap'}         = scalar keys %{ $afpPosFP{$datatype} };
    $curStats{'afp'}{'pos'}{'val'}{'fp'}{$datatype}{'ratio'}            = $ratio;

    my $countAfpPosNV  = scalar keys %{ $afpPosNV{$datatype} };
    $ratio = 0;
    if ($countAfpPos > 0) { $ratio = $countAfpPosNV / $countAfpPos * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpPosNV{$datatype} }) {    $curStats{'afp'}{'pos'}{'nval'}{$datatype}{papers}{$joinkey}++;
                                                              $curStats{'any'}{'pos'}{'nval'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'pos'}{'nval'}{$datatype}{'countPap'}              = scalar keys %{ $afpPosNV{$datatype} };
    $curStats{'afp'}{'pos'}{'nval'}{$datatype}{'ratio'}                 = $ratio;

    my $countAfpPosNC  = scalar keys %{ $afpPosNC{$datatype} };
    $ratio = 0;
    if ($countAfpPos > 0) { $ratio = $countAfpPosNC / $countAfpPos * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpPosNC{$datatype} }) {    $curStats{'afp'}{'pos'}{'ncur'}{$datatype}{papers}{$joinkey}++;
                                                              $curStats{'any'}{'pos'}{'ncur'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'pos'}{'ncur'}{$datatype}{'countPap'}              = scalar keys %{ $afpPosNC{$datatype} };
    $curStats{'afp'}{'pos'}{'ncur'}{$datatype}{'ratio'}                 = $ratio;
  } # foreach my $datatype (@datatypesToShow)
} # sub getCurationStatisticsAfpPos

For AFP Negatives, the following logic is performed to determine the indicated values (list of papers), per datatype:

AFP negative (%afpNeg)
AFP negative validated (%afpNegVal)                             : %afpNeg AND (%valNeg OR %valPos)
AFP negative validated true negative (%afpNegTN)                : %afpNeg AND %valNeg
AFP negative validated false negative (%afpNegFN)               : %afpNeg AND %valPos
AFP negative validated false negative curated (%afpNegFnCur)    : %afpNeg AND %valPos AND %valCur    <Note: the %valPOS is redundant>
AFP negative validated false negative not curated (%afpNegFnNC) : %afpNeg AND %valPos NOT %valCur
AFP negative not validated (%afpNegNV)                          : %afpNeg NOT (%valNeg OR %valPos)
AFP negative not curated (%afpNegNC)                            : (%afpNeg AND (%valPos NOT %valCur)) OR (%afpNeg NOT (%valPos OR %valNeg))

which are determined by the following section of code:

sub getCurationStatisticsAfpNeg {
  my ($datatypesToShow_ref) = @_;
  my @datatypesToShow = @$datatypesToShow_ref;
  my %afpNegNV; my %afpNegVal; my %afpNegTN; my %afpNegFN; my %afpNegFnCur; my %afpNegFnNC; my %afpNegNC;
        # negative and : not validated, validated, true negative, false negative, FN curated, FN not curated, not curated minus validated negative OR not validated + FN not curated
  foreach my $datatype (@datatypesToShow) {
    foreach my $joinkey (sort keys %{ $afpNeg{$datatype} }) {
      if ($valNeg{$datatype}{$joinkey}) {      $afpNegTN{$datatype}{$joinkey}++;    $afpNegVal{$datatype}{$joinkey}++; }
        elsif ($valPos{$datatype}{$joinkey}) { $afpNegFN{$datatype}{$joinkey}++;    $afpNegVal{$datatype}{$joinkey}++;
          if ($valCur{$datatype}{$joinkey}) {  $afpNegFnCur{$datatype}{$joinkey}++; }
            else                            {  $afpNegFnNC{$datatype}{$joinkey}++;  $afpNegNC{$datatype}{$joinkey}++; } }
        else {                                 $afpNegNV{$datatype}{$joinkey}++;    $afpNegNC{$datatype}{$joinkey}++; } } }
  tie %{ $curStats{'afp'}{'neg'} }, "Tie::IxHash";
  foreach my $datatype (@datatypesToShow) {
    my $countAfpFlagged   = scalar keys %{ $afpFlagged{$datatype} };
    my $countAfpNeg = scalar keys %{ $afpNeg{$datatype} };
    my $ratio = 0;
    if ($countAfpFlagged > 0) { $ratio = $countAfpNeg / $countAfpFlagged * 100; $ratio = FormatSigFigs($ratio, 2); }    # ($ratio) = &roundToPlaces($ratio, 2); # $ratio = sprintf "%.2f", $ratio;
    foreach my $joinkey (keys %{ $afpNeg{$datatype} }) { $curStats{'afp'}{'neg'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'neg'}{$datatype}{'countPap'} = scalar keys %{ $afpNeg{$datatype} };
    $curStats{'afp'}{'neg'}{$datatype}{'ratio'}    = $ratio;

    my $countAfpNegVal  = scalar keys %{ $afpNegVal{$datatype} };
    $ratio = 0;
    if ($countAfpNeg > 0) { $ratio = $countAfpNegVal / $countAfpNeg * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpNegVal{$datatype} }) { $curStats{'afp'}{'neg'}{'val'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'neg'}{'val'}{$datatype}{'countPap'} = scalar keys %{ $afpNegVal{$datatype} };
    $curStats{'afp'}{'neg'}{'val'}{$datatype}{'ratio'}    = $ratio;

    my $countAfpNegTN  = scalar keys %{ $afpNegTN{$datatype} };
    $ratio = 0;
    if ($countAfpNegVal > 0) { $ratio = $countAfpNegTN / $countAfpNegVal * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpNegTN{$datatype} }) { $curStats{'afp'}{'neg'}{'val'}{'tn'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'neg'}{'val'}{'tn'}{$datatype}{'countPap'} = scalar keys %{ $afpNegTN{$datatype} };
    $curStats{'afp'}{'neg'}{'val'}{'tn'}{$datatype}{'ratio'}    = $ratio;

    my $countAfpNegFN  = scalar keys %{ $afpNegFN{$datatype} };
    $ratio = 0;
    if ($countAfpNegVal > 0) { $ratio = $countAfpNegFN / $countAfpNegVal * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpNegFN{$datatype} }) { $curStats{'afp'}{'neg'}{'val'}{'fn'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'neg'}{'val'}{'fn'}{$datatype}{'countPap'} = scalar keys %{ $afpNegFN{$datatype} };
    $curStats{'afp'}{'neg'}{'val'}{'fn'}{$datatype}{'ratio'}    = $ratio;

    my $countAfpNegFnCur  = scalar keys %{ $afpNegFnCur{$datatype} };
    $ratio = 0;
    if ($countAfpNegFN > 0) { $ratio = $countAfpNegFnCur / $countAfpNegFN * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpNegFnCur{$datatype} }) { $curStats{'afp'}{'neg'}{'val'}{'fn'}{'cur'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'neg'}{'val'}{'fn'}{'cur'}{$datatype}{'countPap'} = scalar keys %{ $afpNegFnCur{$datatype} };
    $curStats{'afp'}{'neg'}{'val'}{'fn'}{'cur'}{$datatype}{'ratio'}    = $ratio;

    my $countAfpNegFnNC  = scalar keys %{ $afpNegFnNC{$datatype} };
    $ratio = 0;
    if ($countAfpNegFN > 0) { $ratio = $countAfpNegFnNC / $countAfpNegFN * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpNegFnNC{$datatype} }) { $curStats{'afp'}{'neg'}{'val'}{'fn'}{'ncur'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'neg'}{'val'}{'fn'}{'ncur'}{$datatype}{'countPap'} = scalar keys %{ $afpNegFnNC{$datatype} };
    $curStats{'afp'}{'neg'}{'val'}{'fn'}{'ncur'}{$datatype}{'ratio'}    = $ratio;

    my $countAfpNegNV  = scalar keys %{ $afpNegNV{$datatype} };
    $ratio = 0;
    if ($countAfpNeg > 0) { $ratio = $countAfpNegNV / $countAfpNeg * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpNegNV{$datatype} }) { $curStats{'afp'}{'neg'}{'nval'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'neg'}{'nval'}{$datatype}{'countPap'} = scalar keys %{ $afpNegNV{$datatype} };
    $curStats{'afp'}{'neg'}{'nval'}{$datatype}{'ratio'}    = $ratio;

    my $countAfpNegNC  = scalar keys %{ $afpNegNC{$datatype} };
    $ratio = 0;
    if ($countAfpNeg > 0) { $ratio = $countAfpNegNC / $countAfpNeg * 100; $ratio = FormatSigFigs($ratio, 2); }
    foreach my $joinkey (keys %{ $afpNegNC{$datatype} }) { $curStats{'afp'}{'neg'}{'ncur'}{$datatype}{papers}{$joinkey}++; }
    $curStats{'afp'}{'neg'}{'ncur'}{$datatype}{'countPap'} = scalar keys %{ $afpNegNC{$datatype} };
    $curStats{'afp'}{'neg'}{'ncur'}{$datatype}{'ratio'}    = $ratio;
  } # foreach my $datatype (@datatypesToShow)
} # sub getCurationStatisticsAfpNeg

"Any" and "Intersection" rows of the Curation Statistics table

To determine the "Any" and "Intersection" results, all flagging methods currently visible in the Curation Statistics table are considered. So, for the main Curation Statistics table (with no options selected), all flagging methods (SVM, AFP, and CFP as of 12-10-2012) are considered. The calculations in this case would be:

Any flagged                                                     : %svmData      OR %strFlagged   OR %afpFlagged   OR %cfpFlagged
Any positive                                                    : %svmPos       OR %strPos       OR %afpPos       OR %cfpPos
Any positive validated                                          : %svmPosVal    OR %strPosVal    OR %afpPosVal    OR %cfpPosVal
Any positive validated false positive                           : %svmPosFP     OR %strPosFP     OR %afpPosFP     OR %cfpPosFP
Any positive validated true positive                            : %svmPosTP     OR %strPosTP     OR %afpPosTP     OR %cfpPosTP
Any positive validated true positive curated                    : %svmPosTpCur  OR %strPosTpCur  OR %afpPosTpCur  OR %cfpPosTpCur
Any positive validated true positive not curated                : %svmPosTpNC   OR %strPosTpNC   OR %afpPosTpNC   OR %cfpPosTpNC
Any positive not validated                                      : %svmPosNV     OR %strPosNV     OR %afpPosNV     OR %cfpPosNV
Any positive not curated                                        : %svmPosNC     OR %strPosNC     OR %afpPosNC     OR %cfpPosNC
                                                                                     
Intersection flagged                                            : %svmData     AND %strFlagged  AND %afpFlagged  AND %cfpFlagged
Intersection positive                                           : %svmPos      AND %strPos      AND %afpPos      AND %cfpPos
Intersection positive validated                                 : %svmPosVal   AND %strPosVal   AND %afpPosVal   AND %cfpPosVal
Intersection positive validated false positive                  : %svmPosFP    AND %strPosFP    AND %afpPosFP    AND %cfpPosFP
Intersection positive validated true positive                   : %svmPosTP    AND %strPosTP    AND %afpPosTP    AND %cfpPosTP
Intersection positive validated true positive curated           : %svmPosTpCur AND %strPosTpCur AND %afpPosTpCur AND %cfpPosTpCur
Intersection positive validated true positive not curated       : %svmPosTpNC  AND %strPosTpNC  AND %afpPosTpNC  AND %cfpPosTpNC
Intersection positive not validated                             : %svmPosNV    AND %strPosNV    AND %afpPosNV    AND %cfpPosNV
Intersection positive not curated                               : %svmPosNC    AND %strPosNC    AND %afpPosNC    AND %cfpPosNC

Note that if a curator enters the Curation Statistics table after entering deselecting any of the flagging methods in the Curation Statistics Options Page, the "Any" and "Intersection" sections of the table will only reflect the flagging methods chosen by the curator. Thus, if a curator chooses to view only one flagging method, the "Any", "Intersection", and "Flagged Positive" sections of the table will show identical results.

The following are the correspondences between rows in the Curation Statistics table and the hash tables in the form's code:

General paper stats

%curatablePapers                curatable papers
%objsCurated                    objects curated
%objsCurated/%valCur            objects curated per paper
%valCur                         Papers curated
%validated                      Papers validated
%valPos                             Papers validated positive
%valCur                                 Papers validated positive curated
%valPos NOT %valCur                     Papers validated positive not curated
%valNeg                             Papers validated negative
%conflict                           Papers validated conflict

Support Vector Machine paper stats

%noSvm                  SVM no svm processed
%svmData                SVM has svm
%svmPos                     SVM positive any
%svmPosVal                      SVM positive any validated
%svmPosFP                           SVM positive any validated false positive
%svmPosTP                           SVM positive any validated true positive
%svmPosTpCur                            SVM positive any validated true positive curated
%svmPosTpNC                             SVM positive any validated true positive not curated
%svmPosNV                           SVM positive any not validated
%svmPosNC                           SVM positive any not curated
%svmHig	                    SVM positive high
%svmHigVal                      SVM positive high validated
%svmHigFP                           SVM positive high validated false positive
%svmHigTP                           SVM positive high validated true positive
%svmHigTpCur                            SVM positive high validated true positive curated
%svmHigTpNC                             SVM positive high validated true positive not curated
%svmHigNV                           SVM positive high not validated
%svmHigNC                           SVM positive high not curated
%svmMed	                    SVM positive medium
%svmMedVal                      SVM positive medium validated
%svmMedFP                           SVM positive medium validated false positive
%svmMedTP                           SVM positive medium validated true positive
%svmMedTpCur                            SVM positive medium validated true positive curated
%svmMedTpNC                             SVM positive medium validated true positive not curated
%svmMedNV                           SVM positive medium not validated
%svmMedNC                           SVM positive medium not curated
%svmLow	                    SVM positive low
%svmLowVal                      SVM positive low validated
%svmLowFP                           SVM positive low validated false positive
%svmLowTP                           SVM positive low validated true positive
%svmLowTpCur                            SVM positive low validated true positive curated
%svmLowTpNC                             SVM positive low validated true positive not curated
%svmLowNV                           SVM positive low not validated
%svmLowNC                           SVM positive low not curated
%svmNeg	                    SVM negative
%svmNegVal                      SVM negative validated
%svmNegTN                           SVM negative validated true negative
%svmNegFN                           SVM negative validated false negative
%svmNegFnCur                            SVM negative validated false negative curated
%svmNegFnNC                             SVM negative validated false negative not curated
%svmNegNV                           SVM negative not validated
%svmNegNC                           SVM negative not curated

String Matches paper stats

%strFlagged                        STR flagged
%strPos                            STR positive
%strPosVal                             STR positive validated
%strPosFP                                  STR positive validated false positive
%strPosTP                                  STR positive validated true positive
%strPosTpCur                                   STR positive validated true positive curated
%strPosTpNC                                    STR positive validated true positive not curated
%strPosNV                              STR positive not validated
%strPosNC                              STR positive not curated
%strNeg                            STR negative
%strNegVal                             STR negative validated
%strNegTN                                  STR negative validated true negative
%strNegFN                                  STR negative validated false negative
%strNegFnCur                                   STR negative validated false negative curated
%strNegFnNC                                    STR negative validated false negative not curated
%strNegNV                              STR negative not validated
%strNegNC                              STR negative not curated

Author First Pass paper stats

%afpEmailed                        AFP emailed
%afpFlagged                        AFP flagged
%afpPos                            AFP positive
%afpPosVal                             AFP positive validated
%afpPosFP                                  AFP positive validated false positive
%afpPosTP                                  AFP positive validated true positive
%afpPosTpCur                                   AFP positive validated true positive curated
%afpPosTpNC                                    AFP positive validated true positive not curated
%afpPosNV                              AFP positive not validated
%afpPosNC                              AFP positive not curated
%afpNeg                            AFP negative
%afpNegVal                             AFP negative validated
%afpNegTN                                  AFP negative validated true negative
%afpNegFN                                  AFP negative validated false negative
%afpNegFnCur                                   AFP negative validated false negative curated
%afpNegFnNC                                    AFP negative validated false negative not curated
%afpNegNV                              AFP negative not validated
%afpNegNC                              AFP negative not curated

Curator First Pass paper stats

%cfpFlagged                        CFP flagged
%cfpPos                            CFP positive
%cfpPosVal                             CFP positive validated
%cfpPosFP                                  CFP positive validated false positive
%cfpPosTP                                  CFP positive validated true positive
%cfpPosTpCur                                   CFP positive validated true positive curated
%cfpPosTpNC                                    CFP positive validated true positive not curated
%cfpPosNV                              CFP positive not validated
%cfpPosNC                              CFP positive not curated
%cfpNeg                            CFP negative
%cfpNegVal                             CFP negative validated
%cfpNegTN                                  CFP negative validated true negative
%cfpNegFN                                  CFP negative validated false negative
%cfpNegFnCur                                   CFP negative validated false negative curated
%cfpNegFnNC                                    CFP negative validated false negative not curated
%cfpNegNV                              CFP negative not validated
%cfpNegNC                              CFP negative not curated

Postgres Table Structures

cur_curdata table

The cur_curdata table in Postgres has the following structure:

 cur_paper      | text                     | 
 cur_datatype   | text                     | 
 cur_curator    | text                     | 
 cur_curdata    | text                     | 
 cur_selcomment | text                     | 
 cur_txtcomment | text                     | 
 cur_timestamp  | timestamp with time zone |

The following is an example of a Postgres query to return cur_curdata for the paper WBPaper00031688:

testdb=> SELECT * FROM cur_curdata WHERE cur_paper = '00031688';
 cur_paper | cur_datatype | cur_curator | cur_curdata  | cur_selcomment |      cur_txtcomment       |         cur_timestamp         
-----------+--------------+-------------+--------------+----------------+---------------------------+-------------------------------
 00031688  | otherexpr    | two1823     | positive     |                | qwer                      | 2012-11-20 15:48:18.113978-08
 00031688  | geneint      | two2987     | notvalidated | 2              | test test test            | 2012-11-26 17:06:30.550952-08
 00031688  | rnai         | two2987     | notvalidated |                | testing for documentation | 2012-12-13 14:25:13.360082-08
(3 rows)

For a given paper-datatype pair:

cur_paper: Stores the ID # for the WBPaper ID

cur_datatype: Stores the datatype

cur_curator: Stores the curator ID in the format: "two" + "ID # from <WBPersonID>"

cur_curdata: Stores validation status: "positive", "negative", "curated", "notvalidated"

cur_selcomment: Stores the premade comment key (only one value possible by the form; Postgres is OK with more values)

cur_txtcomment: Stores the free-text comment

cur_timestamp: Stores the timestamp for the data submission through the Curation Statistics Form

cur_svmdata table

The cur_svmdata table in Postgres has the following structure:

 cur_paper     | text                     | 
 cur_datatype  | text                     | 
 cur_date      | text                     | 
 cur_svmdata   | text                     | 
 cur_version   | text                     | 
 cur_timestamp | timestamp with time zone

The following is an example of a Postgres query to return cur_svmdata for the paper WBPaper00031688:

testdb=> SELECT * FROM cur_svmdata WHERE cur_paper = '00031688';
 cur_paper | cur_datatype | cur_date | cur_svmdata | cur_version |         cur_timestamp         
-----------+--------------+----------+-------------+-------------+-------------------------------
 00031688  | structcorr   | 20090101 | high        | 0           | 2012-12-02 23:22:07.607586-08
 00031688  | seqchange    | 20090101 | high        | 0           | 2012-12-02 23:22:07.599254-08
 00031688  | rnai         | 20090101 | high        | 0           | 2012-12-02 23:22:07.590835-08
 00031688  | overexpr     | 20090101 | high        | 0           | 2012-12-02 23:22:07.582514-08
 00031688  | otherexpr    | 20090101 | high        | 0           | 2012-12-02 23:22:07.574163-08
 00031688  | newmutant    | 20090101 | high        | 0           | 2012-12-02 23:22:07.565834-08
 00031688  | genereg      | 20090101 | high        | 0           | 2012-12-02 23:22:07.557501-08
 00031688  | geneprod     | 20090101 | NEG         | 0           | 2012-12-02 23:22:07.549171-08
 00031688  | geneint      | 20090101 | high        | 0           | 2012-12-02 23:22:07.540835-08
 00031688  | antibody     | 20090101 | NEG         | 0           | 2012-12-02 23:22:07.532509-08
(10 rows)

For a given paper-datatype pair:

cur_paper: Stores the ID # for the WBPaper ID

cur_datatype: Stores the datatype

cur_date: Stores the date of the SVM directory on Yuling's computer

cur_svmdata: Stores the SVM result: "high", "medium", "low", "NEG"

cur_version: Stores the SVM version (Notify Juancarlos when a new SVM version is used). Note: otherexpr and genereg have entries with version = '2'. The values with version=2 have been populated between timestamps 2013-01-14 12:51:34 and 2020-12-08 04:00:11. These are the results of the manual feature manipulation work that was done with Yuling.

cur_timestamp: Stores the timestamp for when the data was read (by a cronjob) into this cur_svmdata table

cur_strdata table

The cur_strdata table in Postgres has the following structure:

 cur_paper     | text                     | 
 cur_datatype  | text                     | 
 cur_date      | text                     | 
 cur_svmdata   | text                     | 
 cur_version   | text                     | 
 cur_timestamp | timestamp with time zone

The following is an example of a Postgres query to return cur_strdata for the paper WBPaper00024206:

testdb=> SELECT * FROM cur_strdata WHERE cur_paper = '00024206';
 cur_paper | cur_datatype | cur_date |     cur_strdata      | cur_version |         cur_timestamp         
-----------+--------------+----------+----------------------+-------------+-------------------------------
 00024206  | humandisease |          | string               |             | 2014-11-06 08:47:56.430251-08
 00024206  | antibody     |          | preparation Antibody |             | 2014-11-06 08:47:56.451557-08
(2 rows)

For a given paper-datatype pair:

cur_paper: Stores the ID # for the WBPaper ID

cur_datatype: Stores the datatype

cur_date: placeholder in case we have dates later

cur_strdata: Stores the STR result: score for sqf, "string" for humandisease, actual matches for antibody.

cur_version: placeholder in case we have versions later

cur_timestamp: Stores the timestamp for when the data was read (by a cronjob) into this cur_strdata table

Script for Populating STR Data into Postgres (cur_strdata)

The script is located on Tazendra here:

/home/postgres/work/pgpopulation/cur_curation/cur_strdata/populate_str_result.pl

the script runs everyday at 4am, it processes 3 diffenrent datatypes, and always replaces all values in cur_strdata.

Antibody this is the URL where it gets the data from http://textpresso-dev.caltech.edu/azurebrd/wen/anti_protein_wen Antibody splits all values on comma-space and aggregates among the main paper and supplements.

sub processAntibody {
  my %papers;
  my $url = 'http://textpresso-dev.caltech.edu/azurebrd/wen/anti_protein_wen';
  my $page = get $url;
  my (@lines) = split/\n/, $page;
  foreach my $line (@lines) {
    my ($where, $values) = split/\t/, $line;
    my ($paper) = $where =~ m/WBPaper(\d+)/;
    my (@values) = split/, /, $values;                  # aggregate comma-separated values
    foreach my $value (@values) { $papers{$paper}{$value}++; }
  } # foreach my $line (@lines)
  my @groupvalues;
  foreach my $paper (sort keys %papers) {
    my $values = join", ", sort keys %{ $papers{$paper} };
    push @groupvalues, qq(('$paper', 'antibody', NULL, '$values', NULL));
  } # foreach my $paper (sort keys %papers)
  my $groupvalues = join", ", @groupvalues;
  push @pgcommands, qq(INSERT INTO cur_strdata VALUES $groupvalues;);
} # sub processAntibody

Sequence feature this is the URL where it gets the data from http://textpresso-dev.caltech.edu/sequence_feature/fullcorpus_result Sequence Feature stores the score.

sub processSeqfeature {
  my %papers;
  my $url = 'http://textpresso-dev.caltech.edu/sequence_feature/fullcorpus_result';
  my $page = get $url;
  my (@lines) = split/\n/, $page;
  foreach my $line (@lines) {
    my ($where, $score) = split/ /, $line;
    next unless ($score >= 25);                     # only keep is score >= 25
    my ($paper) = $where =~ m/WBPaper(\d+)/;
    unless ($papers{$paper}) { $papers{$paper} = $score; }
  } # foreach my $line (@lines)
  my @groupvalues;
  foreach my $paper (sort keys %papers) {
    push @groupvalues, qq(('$paper', 'seqfeature', NULL, '$papers{$paper}', NULL));
  } # foreach my $paper (sort keys %papers)
  my $groupvalues = join", ", @groupvalues;
  push @pgcommands, qq(INSERT INTO cur_strdata VALUES $groupvalues;);
} # sub processSeqfeature

Human disease this is the URL where it gets the data from http://textpresso-dev.caltech.edu/disease/all_papers_nonReview Human Disease aggregates all main papers and supplements and stores the word 'string'

sub processHumandisease {
  my %papers;
  my $url = 'http://textpresso-dev.caltech.edu/disease/all_papers_nonReview';
  my $page = get $url;
  my (@lines) = split/\n/, $page;
  foreach my $line (@lines) { my ($paper) = $line =~ m/WBPaper(\d+)/; $papers{$paper} = 'string'; }
  my @groupvalues;
  foreach my $paper (sort keys %papers) {
    push @groupvalues, qq(('$paper', 'humandisease', NULL, '$papers{$paper}', NULL));
  }
  my $groupvalues = join", ", @groupvalues;
  push @pgcommands, qq(INSERT INTO cur_strdata VALUES $groupvalues;);
} # sub processHumandisease

String search results are only a set of positive papers. For this form's purposes, all papers that are curatable are considered flagged, and any of those that are not a positive string search match, are considered a negative string search match.

Script for Populating SVM Data into Postgres (cur_svmdata)

The script is located on Tazendra here:

/home/postgres/work/pgpopulation/cur_curation/cur_svmdata/populate_svm_result.pl

Allowable Datatypes

Currently (12-13-2012), the only allowable datatypes for SVM data are:

• antibody
• geneint
• geneprod_GO
• genereg
• newmutant
• otherexpr
• overexpr
• rnai
• seqchange
• structcorr

Populating Papers for which there is only a main paper (no supplements)

Yuling gave us a file of main-only paper IDs and this is stored in the %mainOnly hash.

my %mainOnly;
my $mainOnly_file = '/home/postgres/work/pgpopulation/cur_curation/cur_svmdata/main_only';
open (IN, "<$mainOnly_file") or die "Cannot open $mainOnly_file : $!";
while (my $paper = <IN>) { chomp $paper; $paper =~ s/^WBPaper//; $mainOnly{$paper}++; }
close (IN) or die "Cannot close $mainOnly_file : $!";

Populating SVM dates already in Postgres to avoid re-processing/duplication

The following code checks Postgres for SVM dates to make sure that duplicate SVM data is not loaded into the cur_svmdata table. The %datesDone hash has the directory name/date of when a batch of SVM was processed. The %pg hash holds the paper ID, datatype, and date mapping to the SVM result.

sub populateFromPg {
  $result = $dbh->prepare( "SELECT * FROM cur_svmdata" );
  $result->execute() or die "Cannot prepare statement: $DBI::errstr\n";
  while (my @row = $result->fetchrow) {
    my ( $joinkey, $type, $date, $flag, $version, $timestamp ) = @row;
    $datesDone{$date}++;
    $pg{"$joinkey\t$type\t$date"} = $flag;
  }
} # sub populateFromPg

Reading from Yuling's computer

The SVM results are read from the following URL:

http://131.215.52.209/celegans/svm_results/

The code (below) looks for 'href' links of only digits (numbers) followed by a slash ('/'), ignoring any links that contain non-digits.

  my (@dates) = $root_page =~ m/<a href=\"(\d+)\/\">/g;

For each of those links, the code will skip any that are already present in the %datesDone hash, as they are already in Postgres. Hence, any new results stored in older directories will be missed.

The code then looks for 'href' links to files that have svm results for a given datatype. Matches on links that are made solely of 'word' characters (digits, letters, and underscores)

    my (@date_types) = $date_page =~ m/<a href=\"(\w+)\"/g;

For each of those files, the code maps to the datatype. The SVM file structure begins with digits and underscores, followed by an underscore, followed by an optional 'and_missedPaper_' followed by the datatype. If this structure is not followed, the code will not find this file. Skip if there's no datatype.

      my ($type) = $date_type =~ m/^[\d_]+_(?:and_missedPaper_)?(\w+)$/;

'geneprod' results are called 'geneprod_GO' in svm files, map them to 'geneprod'. If a datatype is not in the allowable datatypes list, skip it and add to error output.

Get the file of results, separate into lines, for each line

• get rid of doublequotes
• tab-separate paper from result
• skip if paper does not begin with "WBPaper<some non-space>"
• separate the paper into the number corresponding to the paper ID and the modifier (e.g. 'concat' or 'sup.1'), if there is no modifier, the modifier is 'main'
• if the paper ID was in the %mainOnly hash, call the modifier 'mainonly'.
• skip unless the modifier is either 'concat' or 'mainonly'.
• skip if the paper-datatype-date is already in postgres (redundant with skipping by dates above)
• put result into the %hash hash.

      my $date_type_url = $date_url . $date_type;
      my $date_type_results_page = get $date_type_url;
      my (@results) = split/\n/, $date_type_results_page;
      foreach my $result (@results) {
        if ($result =~ m/\"/) { $result =~ s/\"//g; }
        my ($paper, $flag) = split/\t/, $result;
        next unless ($paper =~ m/^WBPaper[\S]+/);
        my ($joinkey, $modifier) = &getPaperAndModifier($paper);
        if ($mainOnly{$joinkey}) { $modifier = 'mainonly'; }
        next unless ($modifierWholePaper{$modifier});
        my ($tabKey) = &makeTabKey( $joinkey, $modifier, $type, $date );
        next if ($pg{$tabKey});                 # skip if already in postgres
        $hash{$tabKey} = $flag;
      }

For specific dates/ directories, look at the corresponding <dates>/checkFalseNegatives/ directory for files with SVM results that are negative (NEG).

The code is the same, but the regular expression to match for datatypes is : The SVM file structure begins with digits and underscores, followed by an underscore, followed by an optional 'and_missedPaper_', followed by 'checkFN_', followed by the datatype. If this structure is not followed, the code will not find this file.

      my ($type) = $fn_date_type =~ m/^[\d_]+_(?:and_missedPaper_)?checkFN_(\w+)$/;

The SVM result for all of these are set to NEG (negative).

For each of the values that were entered into %hash, the version is '0' for dates before 2012-06-28, and the version is '1' otherwise.

  my $version = '0';
  if ($date < 20120628) { $version = '0'; }
    else { $version = '1'; }

Enter into postgres cur_svmdata tables the paperID, datatype, svmdate, svm_result, version.

  push @pgcommands, qq(INSERT INTO cur_svmdata VALUES('$joinkey', '$type', '$date', '$flag', '$version'));

Any errors because of invalid datatypes, or SVM results that do not match a WBPaper, nor a paper.something get printed at the end of the output file (change this to email Daniela + Chris).

(TODO set cronjob to run every day at 4am ?)

Abbreviations

AFP - Author First Pass (flagging method)

CFP - Curator First Pass (flagging method)

OA - Ontology Annotator (curation tool)

STR - Textpresso String Matches (flagging method)

SVM - Support Vector Machine (flagging method)

Definitions

curatable - A curatable paper is a paper for which : pap_status = 'valid' AND pap_primary_data = 'primary' AND NOT pap_curation_flags = 'non_nematode'

curated - Any paper that has been curated, as determined by its presence in the OA or in cur_curdata. Note that if a paper is considered 'curated' it is automatically considered 'validated positive'

cur_curdata - The Postgres table that captures, for a given paper-datatype pair, the information captured by this form, including validation status, premade comments, and free-text comments

datatype - A class of data that WormBase curates

flagged - Processed by a flagging method (flagged positive OR negative)

flagging method - Manual or automated method for identifying research articles that contain a particular datatype

validated - Definitively confirmed by a curator to have (or not have) the relevant datatype

Datatypes with no feedback into curation status form for curated papers

Variation (seqchange) -> source flags through SVM and first_pass forms http://textpresso-dev.caltech.edu/transgene/transgenes_in_regular_papers.out

Datatypes not in curation status form

Transgene, this has no svm, but is on first pass forms and papers are flagged based on string search, source of output -> http://textpresso-dev.caltech.edu/transgene/transgenes_in_regular_papers.out