WS240 Models.wrm

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WS240 models

Model Changes

  • This cycle we see 3 model change, 2 effecting the ?Variation Class and on effecting the ?Interaction class

?Variation Model changes

Curator: Kevin

?Variation history tracking - Variations are/were merged (Major reduction in numbers and the creation of a canonical variation WS239 data stored outside a model for this release but will be added back for WS240)

          History Merged_into UNIQUE ?GeneVariation XREF Acquires_merge
                          Acquires_merge ?Variation XREF Merged_into
                          Split_from UNIQUE ?Variation XREF Split_into
                          Split_into ?Variation XREF Split_from

?Variation class Type classification

Type_of_mutation Inversion #Evidence
                 Tandem_duplication #Evidence   

Evidence was missing for Inversion and added a new type Tandem_duplication.


?Interaction

Curator: Chris

Simple changes to the ?Interaction model.


Tags to delete:

?Interaction Interaction_type Genetic Suppression_epistasis
				      Agonistic_epistasis
				      Antagonistic_epistasis
				      Complex_oversuppression
				      Biased_suppression
				      Biased_enhancement
				      Complex_phenotype_bias


Tags to add:

?Interaction Interaction_type Genetic Positive_genetic
				      Complete_suppression
				      Partial_suppression
				      Complete_unilateral_suppression
				      Partial_unilateral_suppression
				      Complete_mutual_suppression
				      Partial_mutual_suppression
				      Positive_epistasis
				      Neutral_genetic
				      Neutral_epistasis
				      Qualitative_epistasis
				      Quantitative_epistasis
				      Opposing_epistasis
	     Detection_method Electrophoretic_mobility_shift_assay_(EMSA)  // A
physical interaction detection technique