Vulval development

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[Processes index]

Vulval development in C. elegans

Signaling pathways

(draw out in wikipathways, connect to reactome)
WNT [EGF] [Notch]

Process steps

Morphogenesis of ventral epithelia

Generation of VPC's
Vulval Precursor Patterning
Generation of the adult
Anchor cell invasion
Morphogenesis of the vulva
Generation of the anchor cell: AC/UV decision

Morphogenesis of uterine epithelia

Uterine patterning: pi cell induction
Uterine patterning: uv1 induction
Patterning of adult cell types: 1° lineage
Patterning of adult cell types: Polarity of 2° lineage

Genes

(from WBook chapter "Vulval development")
apm-1, apx-1, ark-1, bam-2, bar-1, cdf-1, ced-10, ceh-20, cki-1, cog-1, cye-1, dig-1, dpy-22, dpy-23, dsl-1, eff-1, efl-1, egl-13, egl-17, egl-18, egl-19, egl-26, egl-30, egl-38, elt-6, evl-20, gap-1, gpa-5, hda-1, hsp-16.49, ksr-1, lag-2, let-23, let-60, lin-1, lin-3, lin-4, lin-11, lin-12, lin-14, lin-17, lin-18, lin-25, lin-28, lin-29, lin-31, lin-35, lin-39, lin-44, lip-1, lst-1, lst-2, lst-3, lst-4, mab-5, mdt-6, mig-2, par-1, pop-1, rom-1, sem-4, sli-1, sqv-1, sqv-2, sqv-3, sqv-4, sqv-5, sqv-6, sqv-7, sqv-8, sra-13, sur-2, syg-1, unc-62, unc-101, zmp-1, syg-2, lin-15A

Cells

(from WBook chapter "Vulval development")
P4.pa, P8.p, P11, P6.p, P2.p, P8.pp, P3.pa, P1, G1, P1.p, P5.p, P4.p, P9.p, P4.pp, P3.pp, P8.pa, P2, P7.p, P11.p, P3, P3.p

Associated GO assignments